Animal Models of Autoimmune Diseases
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Physiology".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 1983
Special Issue Editors
Interests: mouse model; autoimmune disease; T cell; inflammation; APECED; cytokines
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
The immune system protects the host from infection and disease. However, systemic or organ-specific autoimmune diseases occur if the immune system mistakenly attacks and destroys a healthy body’s own tissues. Multiple factors, including genetic, environmental, hormonal, and immunological factors, and even sex differences, contribute to the development of autoimmune diseases, making autoimmune diseases not only heterogeneous but also complex.
Animal models of autoimmune diseases are invaluable for better understanding the pathogenesis of human autoimmune diseases and the discovery of new therapeutic approaches. Therefore, this Special Issue, “Animal Models of Autoimmune Diseases”, aims to explore preclinical manifestations, the mechanisms underlying causes of diseases, and potentially novel therapeutic approaches that may shed new light on fighting against human autoimmune diseases.
We are pleased to invite you to submit your related work to this Special Issue. This Special Issue aims to address important questions in both basic and preclinical research areas highlighting molecular pathogenic mechanisms of organ-specific and systemic autoimmune diseases, as well as innovative preclinical therapeutic approaches for autoimmune diseases.
For this Special Issue, original research articles and reviews are welcome. Research areas may include (but are not limited to) the following: (1) animal models for organ-specific autoimmune disease; (2) animal models for systemic autoimmune disease; (3) the molecular basis of autoimmune disease; and (4) novel therapeutic targets for treating autoimmune disease.
We look forward to receiving your contributions.
Dr. Feng Zhu
Dr. Keqiang Chen
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biology is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- autoimmune disease
- infection
- innate immunity
- inflammation
- cancer risk
- therapeutic target
- adaptive immunity
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