Biological Control and Molecular Biology of Bacterial Plant Diseases

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Plant Science".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 831

Special Issue Editors


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Guest Editor
Institute of Vegetables and Flowers, Chinese Academy of Agricultural Sciences, Beijing 100081, China
Interests: vegetables diseases; biological control; pathogenesis; functional genes; plant-bacterial interactions; secondary metabolites
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
School of Agriculture and Biotechnology, Sun Yat-Sen University, Guangzhou 510275, China
Interests: bacteriology; bacterial cell cycle; bacterial physiology
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Bacterial plant diseases represent a significant challenge to global agriculture, causing substantial losses in crop productivity and quality. Conventional chemical control methods, while effective, are often associated with unintended consequences, such as environmental contamination and the emergence of resistant pathogen strains. In response, there is a growing emphasis on developing sustainable and eco-friendly biological control strategies. This Special Issue is dedicated to advancing the field by compiling cutting-edge research on the biological control and molecular biology of bacterial plant diseases, fostering scientific dialogue and innovation.

The Special Issue will explore a wide range of topics, including, but not limited to, the utilization of beneficial microorganisms like antagonistic bacteria and endophytes for disease management, molecular mechanisms underlying pathogen–host interactions, and the application of advanced genetic engineering tools such as RNA interference and CRISPR for disease control. Additionally, we will highlight the role of omics technologies—genomics, transcriptomics, and proteomics—in identifying novel resistance genes and biological control agents. We welcome original research articles, comprehensive reviews, and concise communications that contribute to the understanding and advancement of these areas.

We look forward to receiving your contributions.

Dr. Lei Li
Dr. Xiaofeng Zhou
Guest Editors

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Keywords

  • bacterial plant diseases
  • biological control
  • plant pathogens
  • endophytes
  • genomic, transcriptomic, and proteomic studies of antagonistic or pathogenic bacteria interactions
  • pathogenic mechanism

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Published Papers (1 paper)

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Review

21 pages, 980 KiB  
Review
Diffusible Signal Factors and Xylella fastidiosa: A Crucial Mechanism Yet to Be Revealed
by Letizia Portaccio, Marzia Vergine, Mariarosaria De Pascali, Luigi De Bellis and Andrea Luvisi
Biology 2025, 14(3), 303; https://doi.org/10.3390/biology14030303 - 17 Mar 2025
Viewed by 752
Abstract
Xylella fastidiosa (Xf) is a xylem-limited Gram-negative phytopathogen responsible for severe plant diseases globally. Colonization and dissemination on host plants are regulated primarily by diffusible signal factors (DSFs) and quorum sensing (QS) molecules regulating biofilm formation, motility, and virulence factor synthesis. [...] Read more.
Xylella fastidiosa (Xf) is a xylem-limited Gram-negative phytopathogen responsible for severe plant diseases globally. Colonization and dissemination on host plants are regulated primarily by diffusible signal factors (DSFs) and quorum sensing (QS) molecules regulating biofilm formation, motility, and virulence factor synthesis. DSFs play a critical role in the transition of bacteria from adhesion to dispersal phases, influencing plant infection and transmission by vector. Because of Xf’s host range (over 550 plant species), effective containment strategies are highly demanded. In this review, we discuss the molecular mechanism of DSF-mediated signalling in Xf, especially concerning its role in pathogenicity and adaptation. Moreover, we shed light on innovative approaches to manage Xf, including quorum-quenching (QQ) strategies and transgenic plants targeted to disrupt QS pathways. Improved knowledge of DSF interactions with host plants and bacterial communities could provide an entry point for novel, sustainable disease control strategies to decrease Xf’s agricultural and ecological impact. Full article
(This article belongs to the Special Issue Biological Control and Molecular Biology of Bacterial Plant Diseases)
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