Transcription Factors and Signaling Pathways in Tooth and Craniofacial Development
A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Biochemistry and Molecular Biology".
Deadline for manuscript submissions: 28 February 2026 | Viewed by 41
Special Issue Editor
Interests: tooth development; fish models; taste buds; cell signaling pathways; ectodermal organs; pharyngeal arch development
Special Issue Information
Dear Colleagues,
Craniofacial development governs the formation of vital structures such as the jaw, teeth, cranial bones, and sensory organs like taste buds, through tightly regulated cellular and molecular interactions. Disruptions in these processes can lead to a wide range of congenital anomalies.
Understanding the transcriptional networks and signaling pathways involved is critical for uncovering the etiology of these birth defects and for advancing regenerative approaches in dentistry, craniofacial surgery, and developmental therapeutics. These studies also provide insight into the evolutionary conservation of morphogenetic mechanisms across vertebrates.
This Special Issue explores the cellular and molecular mechanisms driving craniofacial development, with a focus on neural crest cells, signaling pathways, and mineralization. Using evolutionary insights and animal models, it aims to deepen understanding of craniofacial morphogenesis and tissue formation.
Suggested themes and article types for submissions
In this Special Issue, original research articles and reviews are welcome. Research areas may include (but not limited to) the following:
- Tooth development
- Pharyngeal arch development
- Neural crest cells induced craniofacial morphogenesis
- Animal models in craniofacial developmental biology
- Evolutionary conserved cell signaling mechanisms in craniofacial development
- Hard tissue development and mineralization
- Taste buds and sensory hair cells development and regeneration
I look forward to receiving your contributions.
Dr. Devi Atukorallaya
Guest Editor
Manuscript Submission Information
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Keywords
- teeth
- taste buds
- facial bones and cartilage
- animal models
- birth defects
- dental hard tissue development and mineralization
- regeneration
- cell signaling pathways
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