Gene–Environment Interactions in Evolutionary Developmental Biology

A special issue of Biology (ISSN 2079-7737). This special issue belongs to the section "Evolutionary Biology".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 1733

Special Issue Editor


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Guest Editor
Department of Biological Sciences, University of Illinois Chicago, Chicago, IL 60607, USA
Interests: evolution; developmental biology; physiology; eco-evo-devo; gene-environment interactions; modeling; drosophila; morphology; allometry; plasticity

Special Issue Information

Dear Colleagues,

The impact of the environment on every aspect of phenotype, including cellular function, physiology, morphology, and behavior, has long been recognized. As early as the seventeenth century, natural philosophers understood phenotypic plasticity—the ability of individual genotypes to produce different phenotypes in different environments—to be a fundamental characteristic of life. However, our understanding of the mechanisms through which the environment contributes to phenotypic variation remains relatively basic, covering only a limited range of environmental factors. Even less well elucidated is the genetic architecture of phenotypic plasticity, despite decades of research describing gene–environment interactions. Meanwhile, organisms are increasingly facing both chronic and acute human-induced environmental changes at local and global scales, heightening the urgency to comprehend their plastic response to this change, and how this plasticity evolves.

This Special Issue seeks to gather papers exploring the mechanistic bases of phenotypic plasticity and gene–environment interactions and their impact on all aspects of phenotype, whether molecular, cellular, physiological, or neurological. We particularly encourage submissions that examine the responses of organisms, including humans, within their natural settings or to anthropogenic stressors, and how these responses evolve. We accept reviews, short communications, methodology papers, and full-length research papers. Our goal is to provide readers with an extensive review of the current research on the mechanisms that determine how organisms react to a changing world, now and in the future.

I look forward to receiving your contributions.

Prof. Dr. Alexander Shingleton
Guest Editor

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Keywords

  • phenotypic plasticity
  • gene–environment interactions
  • genetic architecture of plasticity
  • mechanisms of phenotypic variation
  • anthropogenic stressors
  • evolution of plastic responses

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Published Papers (1 paper)

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Review

15 pages, 2922 KiB  
Review
The Role of Epigenetic Switches in Polyphenism Control: Implications from a Nematode Model for the Developmental Regulation of Alternative Phenotypes
by Sara Wighard and Ralf J. Sommer
Biology 2024, 13(11), 922; https://doi.org/10.3390/biology13110922 - 13 Nov 2024
Cited by 2 | Viewed by 1174
Abstract
Polyphenisms, the capability of organisms to form two or more alternative phenotypes in response to environmental variation, are prevalent in nature. However, associated molecular mechanisms and potential general principles of polyphenisms among major organismal groups remain currently unknown. This review focuses on an [...] Read more.
Polyphenisms, the capability of organisms to form two or more alternative phenotypes in response to environmental variation, are prevalent in nature. However, associated molecular mechanisms and potential general principles of polyphenisms among major organismal groups remain currently unknown. This review focuses on an emerging model system for developmental plasticity and polyphenism research, the nematode Pristionchus pacificus and explores mechanistic insight obtained through unbiased genetic, experimental and natural variation studies. Resulting findings identify a central role for epigenetic switches in the environmental control of alternative phenotypes and their micro–and macroevolution. Several features observed in P. pacificus are shared with insects and plants and might become general principles for the control of polyphenisms during development. Full article
(This article belongs to the Special Issue Gene–Environment Interactions in Evolutionary Developmental Biology)
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