Essential Oils as Natural Antimicrobials: Extraction, Characterization, and Synergistic Applications

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Plant-Derived Antibiotics".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 60

Special Issue Editors


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Guest Editor
Laboratorio de Antioxidantes y Procesos Oxidativos, Instituto de Ciencias Químicas, Facultad de Agronomía y Agroindustrias, Universidad Nacional de Santiago del Estero, CONICET, RN 9, Km 1125, Santiago del Estero 4206, Argentina
Interests: volatile organic compounds; bioinsecticides; repellency; mechanism of action; computational chemistry; bioactivity; molecular docking

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Guest Editor
Laboratorio de Compuestos Bioactivos, Centro de Investigaciones en Biofísica Aplicada y Alimentos (CIBAAL), CONICET—Universidad Nacional de Santiago del Estero, RN 9, Km 1125, Santiago del Estero 4206, Argentina
Interests: antimicrobial peptides; peptide—membrane interactions; natural antimicrobials; green silver nanoparticles; essential oils as antimicrobials
Special Issues, Collections and Topics in MDPI journals

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Guest Editor
Pharmaceutical Sciences Department, Federal Rural University of Rio de Janeiro, Rio de Janeiro 23890-000, Brazil
Interests: pharmacognosy; natural products; essential oil; ethnopharmacology; pharmaceutical science; biological activity; phytochemicals
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

This Special Issue explores the latest advancements in the obtention and chemical characterization of essential oils, focusing on their potential as natural antibiotics and their interactions with commercial antimicrobials. Ethnobotanical studies highlight a vast number of medicinal plants with untapped scientific potential, particularly aromatic species, which have long been recognized in traditional medicine for their therapeutic properties.

Essential oils are aromatic oleaginous liquids extracted from various plant parts, composed primarily of a complex mixture of terpenoids derived from secondary metabolism. This Special Issue will showcase novel extraction methodologies, significant findings on antimicrobial activity, synergistic effects with existing antibiotics, and emerging trends in the development of natural antimicrobial agents.

We welcome contributions from researchers and professionals investigating the mechanisms of action of these bioactive compounds, including their interactions with biological membranes, enzymatic inhibition, resistance mitigation, and synergy with conventional antibiotics. Special attention will be given to studies on bacterial biofilm formation and eradication, as well as the underlying molecular mechanisms driving these processes.

Dr. Sergio A. Rodríguez
Dr. Axel Hollmann
Dr. Douglas Siqueira de Almeida Chaves
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • natural antimicrobials
  • biofilm eradication
  • mechanism of action
  • synergism
  • antagonism
  • cytotoxicity
  • compound isolation
  • membrane interaction
  • enzymatic inhibition
  • DNA interaction
  • oxidative stress

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Published Papers

This special issue is now open for submission.
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