Novel Approaches to Prevent and Combat Antimicrobial Resistance

A special issue of Antibiotics (ISSN 2079-6382).

Deadline for manuscript submissions: 30 November 2025 | Viewed by 117

Special Issue Editor


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Guest Editor
Microbiome Research Centre, St. George and Sutherland Clinical School, Department of Medicine, University of New South Wales, 18 High St., Kensington, Sydney, NSW 2052, Australia
Interests: microbiome; antimicrobial resistance; metagenomic next generation sequencing (mNGS); bioinformatics
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Special Issue Information

Dear Colleagues,

Antimicrobial resistance (AMR) is a critical global health challenge and hidden pandemic, killing millions every year. They threaten the effectiveness of existing treatments with drug-resistant infections. The rise in multidrug-resistant pathogens calls for urgent action to discover and implement innovative approaches to prevent their spread and treat them.

This Special Issue invites original research articles, reviews, and perspectives on novel approaches to tackling and mitigating AMR.

We welcome contributions in, but not limited to, the following areas:

  • Antimicrobial Peptides (AMPs): Discovery, mechanisms, and applications of novel AMPs as next-generation antimicrobials.
  • Novel Antibiotics Screening: Development and testing of new antibiotics, including novel compounds and natural product-based discovery, targeting resistant pathogens with new mechanisms of working.
  • Phage Therapy: The use of bacteriophages/phage cocktails and engineered phages to target drug-resistant infections.
  • Fecal Microbiota Transplantation (FMT): Exploring gut microbiome restoration as a strategy to reduce AMR burden.
  • Dietary and Functional Food Interventions: The role of diet, prebiotics, and probiotics in shaping the microbiome and reducing AMR risks and infectious risk.
  • AMR Prevention Strategies:
    • Antibiotic Stewardship: Optimizing antibiotic use in clinical, agricultural, and veterinary settings.
    • Infection Control Measures: Surveillance, hygiene, and public health strategies to prevent the spread of resistant pathogens.
    • Environmental and One Health Approaches: Understanding how water, soil, animals, and climate change contribute to AMR emergence and implementing strategies to reduce environmental reservoirs of resistance genes.

We encourage interdisciplinary studies that integrate microbiology, bioinformatics, clinical research, and public health to address AMR from a One Health perspective and focus on intervention and prevention.

Dr. Xiaotao Jiang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antimicrobial peptides
  • novel antibiotics screening
  • phage therapy
  • fecal microbiota transplantation (FMT)
  • dietary and functional food interventions
  • AMR prevention strategies

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Published Papers

This special issue is now open for submission.
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