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Antibiotics publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue polices and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Local Antibiotics: Antibiotic Loaded Bone Cement and Drug Containing Medical Devices in Orthopaedic Surgery

edited by Christian O. Fölsch and Klaus Dieter Kühn

submission deadline 15 Mar 2025 | 9 articles | Viewed by 8232 | Submission Open

Keywords: biofilm; antibiotic resistance; implant-associated infections; local antibiotic application; cement spacer; antibacterial substances; antibiotic carrier

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Susceptibility and Clinical Findings of Anaerobic Bacteria, 2nd Edition

edited by

Fernando Cobo

submission deadline 15 Mar 2025 | Viewed by 110 | Submission Open

Keywords: antimicrobials; anaerobes; clinical features; MALDI-TOF MS; molecular methods

Pharmacologic Management of MDR Respiratory and Bacteraemic Infections

edited by

Demosthènes A. Makris

and Konstantinos D. Mantzarlis

submission deadline 15 Mar 2025 | Viewed by 73 | Submission Open

Keywords: pneumonia; bacteraemia; intensive care; MDR infections; antibiotics

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Addressing the Challenge of Antibiotic Resistance with Existing Antibiotics

edited by Xuanxian Peng

submission deadline 15 Mar 2025 | Viewed by 41 | Submission Open

Keywords: antibiotic resistance; antibacterial agents; metabolites; antibiotic-resistant bacteria

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic Resistance: A One-Health Approach, 2nd Edition

edited by

Piera Anna Martino

submission deadline 20 Mar 2025 | 2 articles | Viewed by 7254 | Submission Open

Keywords: antibiotic-resistance; One Health; virulence factors; genomics; novel natural molecules; antimicrobial stewardship

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Preventing Antimicrobial Resistance in Hospitals: Infection Control and Antibiotic Use

edited by Dorota Pastuszak-Lewandoska,

Filip Bielec

and Małgorzata Brauncajs

submission deadline 20 Mar 2025 | 1 articles | Viewed by 919 | Submission Open

Keywords: clinical antibiotic use; hospital infection control; healthcare-associated infections; resistance mitigation strategies; alternative therapies; antibiotic stewardship; molecular mechanisms of AMR; new therapeutic combinations of antibiotics; antimicrobial synergy

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Infection and Treatment of Antibiotic-Resistant ESKAPE Pathogens

edited by

Peng Gao

and Jie Shen

submission deadline 20 Mar 2025 | Viewed by 230 | Submission Open

Keywords: antibiotics; alternatives; anti-virulence; antibiotic adjuvant; pathogen-specific agent; vaccine; bacteriophage; microbiome modulator; anti-biofilm; lysin; materials; nanoparticles

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Discovery and Development of the Novel Antimicrobial Agent—2nd Volume

edited by

Zeinab Khalil

submission deadline 20 Mar 2025 | Viewed by 51 | Submission Open

Keywords: antibiotics; bacteria; fungi; plants; multidrug-resistant pathogens; natural products; mode of action; mechanism of action; drug target; drug development

(This special issue belongs to the Section Novel Antimicrobial Agents)

Nosocomial Infections and Complications in ICU Settings

edited by Ignacio Martín-Loeches

submission deadline 20 Mar 2025 | Viewed by 47 | Submission Open

Keywords: nosocomial infections; critical care; pneumonia; ICU; sepsis

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Epidemiology and Mechanism of Bacterial Resistance to Antibiotics

edited by

Gabriela Loredana Popa

and

Mircea Ioan Popa

submission deadline 31 Mar 2025 | 6 articles | Viewed by 8634 | Submission Open

Keywords: multi-drug resistant (MDR); classic and molecular epidemiology; plasmids; resistance gene

A Themed Issue in Honor of Professor Helen Giamarellou—Outstanding Contributions in the Fields of Antimicrobial Resistance and Difficult-to-Treat Resistance Pathogens

edited by Konstantinos Pontikis

submission deadline 31 Mar 2025 | 1 articles | Viewed by 850 | Submission Open

Keywords: antibiotic stewardship; nosocomial infections; infection control; epidemiology of resistance plus in vitro investigation of underlying resistance mechanisms; infections in the ICU; neutropenic host infections; indicated therapeutic approach of MDR and XDR gram-negative infections; pharmacokinetics/pharmacodynamics of newer antimicrobial agents

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

The Antimicrobial Resistance in the Food Chain

edited by

Irene Dini

submission deadline 31 Mar 2025 | Viewed by 127 | Submission Open

Keywords: food safety; foodborne pathogens; pathways of antimicrobial resistance; antibiotic resistance; phenotypic analyses; molecular analyses; regulatory guidelines; food chemistry

Knowledge, Attitudes and Practices of Antimicrobial Resistance and Stewardship in Primary Care Setting: From Understanding to Informing Interventions

edited by Amanj Kurdi

submission deadline 31 Mar 2025 | Viewed by 113 | Submission Open

Keywords: antimicrobial resistance; antimicrobial stewardship; primary care; knowledge; attitudes and practices; antimicrobial stewardship interventions

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Emerging Challenges in Food Safety: Addressing Antimicrobial Resistance, Virulence Factors, and Biofilm Formation in Food-Borne Pathogens

edited by

Liora Mihaela Colobățiu

, Marian Mihaiu and

Zorita Diaconeasa

submission deadline 31 Mar 2025 | Viewed by 78 | Submission Open

Keywords: antimicrobial resistance; food-borne pathogens; food safety; virulence factors; biofilm formation; resistance genes; food production; public health; molecular epidemiology; infection control

Molecular Epidemiology and Antimicrobial Resistance Trends in Gram-Negative Bacteria and Mycobacterium tuberculosis

edited by

Karla Valéria Batista Lima

Yan Corrêa Rodrigues

and

Danielle Murici Brasiliense

submission deadline 31 Mar 2025 | Viewed by 77 | Submission Open

Keywords: antimicrobial resistance (AMR); gram-negative bacteria; mycobacterium tuberculosis; nontuberculous mycobacteria; molecular epidemiology; drug resistance mechanisms; virulence traits; carbapenem-resistant Enterobacterales; drug-resistant TB

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Antibiotic and Antiparasitic Resistance in Veterinary Clinical Settings

edited by

Daphne Lianou

submission deadline 31 Mar 2025 | Viewed by 61 | Submission Open

Keywords: animal; cattle; cat; dog; goat; horse; pig; poultry; sheep; therapeutics; treatment; veterinary; wildlife

(This special issue belongs to the Section Antibiotics in Animal Health)

Biotechnological Production of Novel Antimicrobials

edited by

Vanja Vlajkov

Jovana Grahovac

and

Ivana Danilov

submission deadline 31 Mar 2025 | Viewed by 60 | Submission Open

Keywords: antibiotic resistance; biotechnology; antimicrobial activity; disease outbreak; pathogens; microorganisms; genetic engineering; artificial intelligence; optimisation; biocontrol

Multidurg Resistant Enterobacterales: Mechanisms, Epidemiology and Diagnostics

edited by José Manuel Ortiz De La Rosa and

Mustafa Sadek

submission deadline 31 Mar 2025 | Viewed by 57 | Submission Open

Keywords: multidrug-resistant Enterobacterales; dissemination; detection; β -lactamases; genomics

Environmental Fate and Effects of Antibiotics and Antibiotic Resistance Genes, 2nd Edition

edited by

Anna Barra Caracciolo

submission deadline 31 Mar 2025 | Viewed by 54 | Submission Open

Keywords: antibiotic-resistant bacteria; antibiotic resistance genes; environmental spread; bioaccumulation; biodegradation; antibiotic mixture

Innovative Antimicrobial Strategies to Combat Antibiotic Resistance

edited by

Chenxi Huang

and

Xiaohong Wang

submission deadline 31 Mar 2025 | Viewed by 54 | Submission Open

Keywords: nanotechnology applications; diagnostic strategies; phages-mediated strategies; foodborne pathogens; antibiotics; antimicrobial; multi-drug resistance; biocontrol

Antibiotics in the Environment: Sources, Fate, and Mitigation Strategies

edited by Khaled Benis

submission deadline 31 Mar 2025 | Viewed by 51 | Submission Open

Keywords: antibiotic contamination; environmental fate; antibiotic resistance; mitigation strategies; pollution management

Multidrug-Resistance Patterns in Infectious Pathogens

edited by José Alejandro Di Conza and Barbara Ghiglione

submission deadline 31 Mar 2025 | Viewed by 48 | Submission Open

Keywords: MDR; DTR; antimicrobial resistance; genomics; surveillance; carbapenemases; MRSA; VISA

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Pathogenesis, Epidemiology and Antibiotic Resistance of Salmonella

edited by

Angela Pista

and

Leonor Silveira

submission deadline 31 Mar 2025 | Viewed by 19 | Submission Open

Keywords: Salmonella; epidemiology; genomics; public health; antimicrobial resistance; One-Health approach

Antibiotics Use in Livestock and Poultry

edited by Ana L.P. Mateus

submission deadline 31 Mar 2025 | Viewed by 12 | Submission Open

Keywords: antimicrobial use; veterinary medical use; antimicrobial growth promotion; interventions; antimicrobial resistance; livestock; poultry

(This special issue belongs to the Section Antibiotics in Animal Health)

Antibacterial Utilisation from Different Perspectives: An Effective Tool to Develop and Evaluate Antimicrobial Stewardship Interventions

edited by

Soós Gyöngyvér

and

Ria Benkő

submission deadline 31 Mar 2025 | Viewed by 10 | Submission Open

Keywords: quality of antibiotic use; scale of antibiotic use; pattern of antibiotic use; prevalence of antibiotic use; specific patient populations; safety of use; antibacterial; antivirals; antifungals; anti-TBC

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Fungal Metabolites and Synthetic Derivatives: Antimicrobial Properties Toward Microbial Pathogens

edited by João Vicente Braga De Souza

submission deadline 31 Mar 2025 | Viewed by 8 | Submission Open

Keywords: antimicrobial resistance; fungal metabolites; synthetic derivatives; antifungal agents; bioactive compounds

(This special issue belongs to the Section Fungi and Their Metabolites)

Rapid Antibiotic Susceptibility Testing

edited by Ahmad Salman and Itshak Lapidot

submission deadline 15 Apr 2025 | 2 articles | Viewed by 1634 | Submission Open

Keywords: bacterial infection; antibiotic; multi-drug resistance; bacterial susceptibility to antimicrobials; bacterial culturing; spectroscopy; machine learning

Antibiotic Resistance in Wastewater Treatment Plants

edited by Qingbin Yuan

submission deadline 15 Apr 2025 | 1 articles | Viewed by 751 | Submission Open

Keywords: antibiotic resistance genes; wastewater treatment; one health; distribution and removal of ARGs; horizontal gene transfer

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Comprehensively Addressing Antimicrobial Resistance, Improving Food Safety and Achieving the One Health Goals: Global Challenges

edited by

Vladimir Kurćubić

, Pavle Mašković, Milan Mitić and

Nikola Stanišić

submission deadline 15 Apr 2025 | Viewed by 109 | Submission Open

Keywords: antimicrobial resistance (AMR); food safety; foodborne pathogens; antibiotic residues; natural antimicrobials; one health

Discovery and Synthesis of Antimicrobial Compounds against Multidrug Resistance

edited by

Anita Cohen

submission deadline 15 Apr 2025 | Viewed by 58 | Submission Open

Keywords: antimicrobial resistance; medicinal chemistry; (pre)clinical development; intrinsic/synergistic activity; innovative antibiotic treatment; antimicrobial drug-candidate; new and repurposed medicines

(This special issue belongs to the Section Novel Antimicrobial Agents)

The Use of Antibiotics in Aquaculture: Antimicrobial Resistance, Efficacy and Safety, Ethical and Environmental Concerns

edited by

Øivind Bergh

submission deadline 20 Apr 2025 | 2 articles | Viewed by 3101 | Submission Open

Keywords: antibacterial agents; antimicrobial resistance; aquaculture

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antimicrobial Resistance and Zoonoses, 2nd Edition

edited by

Marina Spînu

and

Magdalena Rzewuska

submission deadline 20 Apr 2025 | 1 articles | Viewed by 1057 | Submission Open

Keywords: antibiotics; antimicrobial resistance; antimicrobial resistance genes; monitoring; one health; pathogen transmission; resistance mechanisms; surveillance; zoonotic pathogens; zoonosis

Innovations in Antibacterial Agents: Combating Resistance, Improving Efficacy and Exploring New Mechanisms

edited by

Rok Frlan

and

Martina Hrast

submission deadline 30 Apr 2025 | 2 articles | Viewed by 2161 | Submission Open

Keywords: drug design; synthesis of novel antibacterial agents; computational chemistry; repurposing of drugs; novel antibacterial mechanisms

(This special issue belongs to the Section Novel Antimicrobial Agents)

The Spread of Antibiotic Resistance in Natural Environments

edited by

Daniel Gyamfi Amoako

submission deadline 30 Apr 2025 | Viewed by 370 | Submission Open

Keywords: antibiotic resistance dissemination; antibiotic pollution; environmental adaptation; mobile genetic elements; ecological impact; environmental microbiome; resistance gene transfer; resistance hotspot; genomic landscape; One Health approach; emerging contaminants; bioinformatics in environmental genomics

(This special issue belongs to the Section The Global Need for Effective Antibiotics)

Antimicrobial Resistance and Environmental Health, 2nd Edition

edited by

Akebe Luther King Abia

submission deadline 30 Apr 2025 | Viewed by 313 | Submission Open

Keywords: public health; environmental health; antibiotic resistance; environmental resistome; antibiotic-resistant bacteria; whole-genome sequencing; metagenomics; climate change and AMR; AMR models and One Health

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Staphylococcus aureus Skin and Soft Tissue Infections Pathogenesis and Therapeutic Approaches, 2nd Edition

edited by

Marisa I. Gómez

Cintia González

and Constanza Giai

submission deadline 30 Apr 2025 | Viewed by 206 | Submission Open

Keywords: Staphylococcus aureus; pathogenesis; skin; skin and soft tissue infections; antimicrobial resistance; adaptation; host response

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Bone and Joint Infections: The Challenges of Prevention, Diagnosis and Treatment and Opportunities for Future Research

edited by

Natividad Benito

submission deadline 30 Apr 2025 | Viewed by 55 | Submission Open

Keywords: bone and joint infection; arthroplasty infection; definition of bone and joint infection; bone and joint joint infection prevention; diagnosis of bone and joint infection; bone and joint infection management; antimicrobial therapy of bone and joint infection

Urinary Tract Infections and Antibiotic Intervention, 2nd Edition

edited by

Majid Mirzazadeh

submission deadline 30 Apr 2025 | Viewed by 40 | Submission Open

Keywords: UTI; antibiotic; microbiome; PCR; next-generation sequencing; urine culture; enhanced quantitative urine cultures; urinary sepsis

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Antibiotic Resistance and the Responsible Use of Antibiotics in Human and Veterinary Medicine

edited by Horvat Olga

submission deadline 30 Apr 2025 | Viewed by 16 | Submission Open

Keywords: antibiotics; antimicrobial resistance; human medicine; veterinary medicine; infection

Antibiotic Resistance and Virulence Mechanisms in Gram-Negative Bacteria: An Alliance for Success

edited by Virginia Garcia-Fulgueiras

submission deadline 1 May 2025 | Viewed by 43 | Submission Open

Keywords: virulence; Gram-negative; antimicrobial resistance; One Health

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Machine Learning for Antimicrobial Resistance Prediction, 2nd Edition

edited by

Asad Mustafa Karim

submission deadline 15 May 2025 | Viewed by 44 | Submission Open

Keywords: antimicrobial resistance prediction; artificial intelligence; machine learning; infectious diseases

Genomic Analysis of Drug-Resistant Pathogens

edited by

Erica Diani

submission deadline 20 May 2025 | Viewed by 37 | Submission Open

Keywords: multi-drug resistant; mutation; bacteria; NGS; sequencing; mobile genetics elements; gene transfer

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

Metagenomics for Surveillance of Pathogens and/or Antimicrobial Resistance

edited by Rommel Thiago Jucá Ramos

submission deadline 31 May 2025 | 1 articles | Viewed by 2724 | Submission Open

Keywords: antimicrobial resistance; metagenomics; pathogen; environmental surveillance; clinical; one health

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

The One Health Action Plan against Antimicrobial Resistance

edited by

Anna Maria Spagnolo

submission deadline 31 May 2025 | Viewed by 194 | Submission Open

Keywords: one health approach; antimicrobial resistance; healthcare-associated infections; food contamination; environment and antibiotic resistance; surveillance; prevention and control

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Therapy of Infectious Diseases Among Children and Adults: The Role of Antibiotics in Daily Practice

edited by

Magdalena Baymakova

and

Valeri R. Velev

submission deadline 31 May 2025 | Viewed by 120 | Submission Open

Keywords: аntibiotic use among children; аntibiotic use among adults; аntibiotic use among outpatients; аntibiotic use among inpatients; antibiotic resistance; improper antibiotic use; antibiotic quality control

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Optimizing Antimicrobial Therapy in NICU Settings: Strategies and Implications

edited by

Elias Iosifidis

and

Angeliki Kontou

submission deadline 31 May 2025 | Viewed by 76 | Submission Open

Keywords: neonatal ICU; antimicrobial stewardship; antimicrobial resistance; neonatal sepsis; biomarkers

(This special issue belongs to the Section Antibiotic Therapy in Infectious Diseases)

Antimicrobial and Antioxidant Efficacy of Essential Oils

edited by

Mijat Božović

submission deadline 15 Jun 2025 | Viewed by 110 | Submission Open

Keywords: essential oils; chemical analysis; extraction methods; antimicrobial activity; antioxidant potential

(This special issue belongs to the Section Plant-Derived Antibiotics)

Antimicrobial Activities of Bioactive Components from Honeybee Products

edited by

Otilia Bobis

Adriana Cristina Urcan

and

Claudia Pașca

submission deadline 30 Jun 2025 | Viewed by 412 | Submission Open

Keywords: bee products; antibiotics; antimicrobial activity; bioactive compounds; honey; propolis; bee pollen/beebread; royal jelly; bee venom; microbial resistance

Multidrug-Resistant Gram-Negative Bacteria Infections: Current Epidemiology, Prognosis and Treatment Options

edited by Novella Carannante

submission deadline 30 Jun 2025 | Viewed by 284 | Submission Open

Keywords: multidrug-resistant gram-negative bacteria; epidemiology and prognosis; antibiotic treatment options; antimicrobial resistance; infection control and antibiotic use

(This special issue belongs to the Section Antibiotics Use and Antimicrobial Stewardship)

Recent Advances in Efflux Pump Inhibitors and Their Role in Combatting Multidrug Resistance

edited by

László Orosz

and

Spengler Gabriella

submission deadline 30 Jun 2025 | Viewed by 60 | Submission Open

Keywords: multidrug resistance; multidrug efflux pump; efflux pump inhibitor (EPI); accumulation assay; efflux assay; fluorochromes; ethidium bromide; quorum sensing; biofilm

(This special issue belongs to the Section Mechanism and Evolution of Antibiotic Resistance)

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