Structure and Function of Antimicrobial Peptides
A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antimicrobial Peptides".
Deadline for manuscript submissions: 31 October 2025 | Viewed by 564
Special Issue Editors
Interests: antimicrobial peptides; peptide flexibility; peptide/lipid interactions; cyclic lipopeptides
Interests: regulation of innate immunity; antimicrobial peptides; antifungal peptides; defensins; cathelicidins; novel antiviral compounds
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
In the constant search for therapeutic alternatives to control the emergence of resistance in microbial pathogens, we often return to nature. We have been assembling an arsenal of bioactive compounds with antimicrobial potential since their discovery in animal sources, such as the skin secretions of amphibians, the venom of some arthropods and reptiles, and the exudates of multiple bacteria. Today, more than 22,000 natural and modified peptides are available in the DBAASP database. This biological toolkit has great therapeutic potential.
These peptides interact with lipid membranes, stabilizing aqueous pores or carrying out micellization processes as biodetergents. However, many molecular details regarding their bioactivity remain poorly elucidated, and the possible mechanisms behind their synergistic action with other antimicrobial agents are still poorly explored. Thus, to achieve a better understanding of these peptides and to take advantage of their pharmacological potential, it is necessary to take advantage of several biophysical and computational tools for their study. In addition, lipidomic studies are of great importance, since they will allow us to have a better idea of the role played by lipid composition in the structural reconfiguration undergone by these peptides during their interaction with the lipid membrane.
Dr. Daniel Balleza
Prof. Dr. Gill Diamond
Guest Editors
Manuscript Submission Information
Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.
Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.
Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.
Keywords
- antimicrobial peptides
- natural peptides
- lipidomics
- synergistic action
- bioactivity mechanisms
- structure reconfiguration
Benefits of Publishing in a Special Issue
- Ease of navigation: Grouping papers by topic helps scholars navigate broad scope journals more efficiently.
- Greater discoverability: Special Issues support the reach and impact of scientific research. Articles in Special Issues are more discoverable and cited more frequently.
- Expansion of research network: Special Issues facilitate connections among authors, fostering scientific collaborations.
- External promotion: Articles in Special Issues are often promoted through the journal's social media, increasing their visibility.
- e-Book format: Special Issues with more than 10 articles can be published as dedicated e-books, ensuring wide and rapid dissemination.
Further information on MDPI's Special Issue policies can be found here.
