Novel Preventive and Therapeutic Strategies to Eradicate Biofilm Infections Based on New Antibacterial Compounds

A special issue of Antibiotics (ISSN 2079-6382). This special issue belongs to the section "Antibiofilm Strategies".

Deadline for manuscript submissions: 31 October 2025 | Viewed by 55

Special Issue Editor


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Guest Editor
Department of Clinical Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, 28007 Madrid, Spain
Interests: biofilms; prostheses; infection; devices; catheter
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Biofilm-related infections pose a significant challenge in modern medicine, contributing to persistent and treatment-resistant infections. The limited efficacy of conventional antibiotics against biofilms, coupled with the rise of antimicrobial resistance (AMR), underscores the urgent need for innovative therapeutic and preventive strategies. This Special Issue focuses on novel antibacterial compounds and alternative approaches to combat biofilm infections, aiming to reduce reliance on traditional antibiotics. We welcome the submission of original research papers, short communications, reviews, case reports, and perspectives on, but not limited to, the following topics:

  • Novel antibacterial agents targeting biofilms;
  • Combination therapies for enhanced biofilm eradication;
  • Anti-biofilm peptides and enzymes;
  • Bacteriophage-based strategies;
  • Immunotherapeutic and host-directed approaches;
  • Biomaterial innovations to prevent biofilm formation;
  • Natural and synthetic inhibitors of biofilm development;
  • Gut microbiota modulation for biofilm control.

Submitted manuscripts should emphasize strategies for overcoming biofilm-related infections while minimizing antibiotic dependence.

Dr. María Guembe
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Antibiotics is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2900 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • antibacterial
  • biofilm
  • infection
  • innovation
  • microbiota

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Published Papers

This special issue is now open for submission.
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