MMCS 2019 2019 - 117 articles
Barcelona, Spain | 15–17 May 2019
Volume Editor:
Diego Muñoz-Torrero, University of Barcelona, Spain
F. Javier Luque, University of Barcelona, Spain
The Nedd4-1 E3 Ubiquitin ligase has been implicated in multiple disease conditions due its overexpression. Although the Nedd4-1 E3 Ubiquitin ligase is an enzyme that may be targeted either covalently, or non-covalently, there are few studies that dem...
1,2,3-triazole is a well-known scaffold that is. [...]
Staphylococcus aureus is a widespread gram-positive pathogen in humans and animals. Autolysin E (AtlE) is an enzyme from S. aureus which belongs to the glycoside hydrolase 73 family. [...]
The Plasminogen system is known for being responsible. [...]
Fragment-based drug discovery (FBDD) has become a major strategy to derive novel lead candidates for both new and established therapeutic targets, as it promises efficient exploration of chemical space by employing fragment-sized (MW 300) compounds....
Influenza epidemics are estimated to result in 3–5 million cases of severe illness and 290.000–650.000 deaths per year. [...]
The ubiquitine–proteasome pathway (UPP) plays. [...]
The proteasome degrade most of the proteins in eukaryotic cells, thereby controlling the key cellular processes [...]
Proteolysis targeting chimera molecules (PROTACS) are heterobifunctional small molecules designed to induce intracellular protein degradation [...]
Neuroblastoma is the most common solid malignancy in early. [...]
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