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Open AccessAbstract

The Targeting of Quadruplex Nucleic Acids in Human Cancers

School of Pharmacy, University College London, London WC1N 1AX, UK
Presented at the 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15–17 May 2019.
Proceedings 2019, 22(1), 68;
Published: 13 August 2019
(This article belongs to the Proceedings of The Molecules Medicinal Chemistry Symposium)
PDF [141 KB, uploaded 13 August 2019]
Note: In lieu of an abstract, this is an excerpt from the first page.


The overwhelming majority of DNA in the human genome is double-stranded. However,
regions comprising several short guanine-tracts are capable of forming higher-order structures,
termed quadruplexes. [...]
Keywords: quadruplex; cancer; pancreatic cancer quadruplex; cancer; pancreatic cancer
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).

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Neidle, S. The Targeting of Quadruplex Nucleic Acids in Human Cancers. Proceedings 2019, 22, 68.

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