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Promising Approach to Inhibit E. coli FimH Adhesion by C-Linked Mannosides

Department of Chemistry, Université du Québec à Montréal, P.O. Box 8888, Succ. Centre-Ville, Montréal, QC H3C 3P8, Canada
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Presented at the 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15–17 May 2019.
Proceedings 2019, 22(1), 1; https://doi.org/10.3390/proceedings2019022001
Published: 6 August 2019
(This article belongs to the Proceedings of The Molecules Medicinal Chemistry Symposium)
PDF [284 KB, uploaded 6 August 2019]
Note: In lieu of an abstract, this is an excerpt from the first page.

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Antagonists of the uropathogenic Escherichia coli type-1 fimbrial adhesin (FimH) are recognized as attractive alternatives for antibiotic therapies and prophylactic strategies against acute and recurrent bacterial infections. [...]
Keywords: carbohydrate; D-mannosides; uropathogenic infections; E. coli; lectin; FimH carbohydrate; D-mannosides; uropathogenic infections; E. coli; lectin; FimH
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Mousavifar, L.; Roy, R. Promising Approach to Inhibit E. coli FimH Adhesion by C-Linked Mannosides. Proceedings 2019, 22, 1.

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