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Open AccessExtended Abstract

Mechanisms of Inhibitory Effects of Polysubstituted Pyrimidines on Prostaglandin E2 Production

1
Institute of Experimental Medicine, The Czech Academy of Sciences, 142 20 Prague, Czech Republic
2
Institute of Organic Chemistry and Biochemistry, The Czech Academy of Sciences, 166 10 Prague, Czech Republic
*
Author to whom correspondence should be addressed.
Presented at the 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15–17 May 2019.
Proceedings 2019, 22(1), 24; https://doi.org/10.3390/proceedings2019022024
Published: 7 August 2019
(This article belongs to the Proceedings of The Molecules Medicinal Chemistry Symposium)
Note: In lieu of an abstract, this is an excerpt from the first page.

The pyrimidine heterocycle represents an elemental structural motif of numerous drugs. [...]
Keywords: pyrimidine analogues; prostaglandin E2; prostaglandin E2 synthase-1 inhibitors; anti-inflammatory activity pyrimidine analogues; prostaglandin E2; prostaglandin E2 synthase-1 inhibitors; anti-inflammatory activity
MDPI and ACS Style

Zídek, Z.; Kolman, V.; Baszczyňski, O.; Kalčic, F.; Board, D.; Janeba, Z. Mechanisms of Inhibitory Effects of Polysubstituted Pyrimidines on Prostaglandin E2 Production. Proceedings 2019, 22, 24.

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