Next Article in Journal
Towards the Modulation of RNA-Binding Proteins: New Compounds Targeting Protein HuR
Previous Article in Journal
In Search of Selectivity: Design, Synthesis, and Biological Evaluation of New Classes of HDAC Inhibitors
Article Menu

Article Versions

Export Article

Open AccessExtended Abstract

Synthesis and Biological Evaluation of Aminobisphosphonates—Analogues of Incadronate

1
Department of Bioorganic Chemistry, Faculty of Chemistry, Wrocław University of Science and Technology, Wybrzeże Wyspiańskiego 27, 50-370 Wrocław, Poland
2
Department of Biostructure and Animal Physiology, The Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Norwida 31, 50-375 Wrocław, Poland
3
Department of Experimental Oncology, Hirszfeld Institute of Immunology and Experimental Therapy, Polish Academy of Sciences, R. Weigla 12, 53-114 Wrocław, Poland
4
Department of Surgery, The Faculty of Veterinary Medicine, Wrocław University of Environmental and Life Sciences, Norwida 31, 50-375 Wrocław, Poland
*
Author to whom correspondence should be addressed.
Presented at the 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15–17 May 2019.
Proceedings 2019, 22(1), 64; https://doi.org/10.3390/proceedings2019022064
Published: 12 August 2019
(This article belongs to the Proceedings of The Molecules Medicinal Chemistry Symposium)
PDF [192 KB, uploaded 12 August 2019]
Note: In lieu of an abstract, this is an excerpt from the first page.

Excerpt

Bisphosphonates had been found to act as strong metal ion complexing agents with useful
industrial and household applications. [...]
Keywords: bisphosphonic acid; biological activity; synthesis of aminomethylenebisphosphonates; three-component reaction; anti-proliferative activity; in-vivo studies; antiosteoporotic activity bisphosphonic acid; biological activity; synthesis of aminomethylenebisphosphonates; three-component reaction; anti-proliferative activity; in-vivo studies; antiosteoporotic activity
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
SciFeed

Share & Cite This Article

MDPI and ACS Style

Chmielewska, E.; Kuryszko, J.; Wietrzyk, J.; Kiełbowicz, Z.; Kafarski, P. Synthesis and Biological Evaluation of Aminobisphosphonates—Analogues of Incadronate. Proceedings 2019, 22, 64.

Show more citation formats Show less citations formats

Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Metrics

Article Access Statistics

1

Comments

[Return to top]
Proceedings EISSN 2504-3900 Published by MDPI AG, Basel, Switzerland RSS E-Mail Table of Contents Alert
Back to Top