Comparative Studies on the Human Serum Albumin Binding of the Investigational EGFR Inhibitor KP2187, Its Hypoxia-Activated Cobalt Complex, and a Series of Clinically Approved Inhibitors

Enyedy, Eva Anna; Dömötör, Orsolya; Borics, Attila; Keppler, Bernhard K.; Kowol, Christian R.

doi:10.3390/proceedings2019022027

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Comparative Studies on the Human Serum Albumin Binding of the Investigational EGFR Inhibitor KP2187, Its Hypoxia-Activated Cobalt Complex, and a Series of Clinically Approved Inhibitors^†

by

Eva Anna Enyedy

^1,*

,

¹,

²,

^3,4 and

^3,4

¹

Department of Inorganic and Analytical Chemistry, Interdisciplinary Excellence Centre, University of Szeged, Dóm tér 7, H-6720 Szeged, Hungary

²

Institute of Biochemistry, Biological Research Centre, Hungarian Academy of Sciences, Temesvári krt. 62, H-6726 Szeged, Hungary

³

Institute of Inorganic Chemistry, Faculty of Chemistry, University of Vienna, Waehringer Strasse 42, 1090 Vienna, Austria

⁴

Research Cluster “Translational Cancer Therapy Research”, Medical University of Vienna, 1090 Vienna, Austria

^*

Author to whom correspondence should be addressed.

^†

Presented at the 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15–17 May 2019.

Proceedings 2019, 22(1), 27; https://doi.org/10.3390/proceedings2019022027

Published: 7 August 2019

(This article belongs to the Proceedings of The 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery)

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Binding interactions between human serum albumin and four clinically approved epidermal [...]

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MDPI and ACS Style

Enyedy, E.A.; Dömötör, O.; Borics, A.; Keppler, B.K.; Kowol, C.R. Comparative Studies on the Human Serum Albumin Binding of the Investigational EGFR Inhibitor KP2187, Its Hypoxia-Activated Cobalt Complex, and a Series of Clinically Approved Inhibitors. Proceedings 2019, 22, 27. https://doi.org/10.3390/proceedings2019022027

AMA Style

Enyedy EA, Dömötör O, Borics A, Keppler BK, Kowol CR. Comparative Studies on the Human Serum Albumin Binding of the Investigational EGFR Inhibitor KP2187, Its Hypoxia-Activated Cobalt Complex, and a Series of Clinically Approved Inhibitors. Proceedings. 2019; 22(1):27. https://doi.org/10.3390/proceedings2019022027

Chicago/Turabian Style

Enyedy, Eva Anna, Orsolya Dömötör, Attila Borics, Bernhard K. Keppler, and Christian R. Kowol. 2019. "Comparative Studies on the Human Serum Albumin Binding of the Investigational EGFR Inhibitor KP2187, Its Hypoxia-Activated Cobalt Complex, and a Series of Clinically Approved Inhibitors" Proceedings 22, no. 1: 27. https://doi.org/10.3390/proceedings2019022027

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Comparative Studies on the Human Serum Albumin Binding of the Investigational EGFR Inhibitor KP2187, Its Hypoxia-Activated Cobalt Complex, and a Series of Clinically Approved Inhibitors^†

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Comparative Studies on the Human Serum Albumin Binding of the Investigational EGFR Inhibitor KP2187, Its Hypoxia-Activated Cobalt Complex, and a Series of Clinically Approved Inhibitors †

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Comparative Studies on the Human Serum Albumin Binding of the Investigational EGFR Inhibitor KP2187, Its Hypoxia-Activated Cobalt Complex, and a Series of Clinically Approved Inhibitors^†