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Open AccessExtended Abstract

Dibenzylxanthines as PPEPCK-M Inhibitors for Cancer Therapy

1
Department of Physiological Sciences, Faculty of Medicine, University of Barcelona, 08907 L’Hospitalet de Llobregat, Spain
2
Department of Pharmacology and Medicinal Chemistry, Faculty of Pharmacy, and Institute of Biomedicine (IBUB), University of Barcelona, 08028 Barcelona, Spain
3
Institut D'Investigació Biomèdica de Bellvitge (IDIBELL), 08907 L’Hospitalet de Llobregat, Spain
4
Farmacologia Terapèutica i Toxicologia, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain
*
Author to whom correspondence should be addressed.
Presented at the 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15–17 May 2019.
Proceedings 2019, 22(1), 79; https://doi.org/10.3390/proceedings2019022079
Published: 16 August 2019
(This article belongs to the Proceedings of The Molecules Medicinal Chemistry Symposium)
Note: In lieu of an abstract, this is an excerpt from the first page.

Phosphoenolpyruvate carboxykinase (PEPCK) is the key enzyme in gluconeogenesis/glyceroneogenesis, which catalyzes the decarboxylation of oxaloacetate to phosphoenolpyruvate. [...]
MDPI and ACS Style

Aragó, M.; Rodríguez-Arévalo, S.; Hyrossova, P.; Moreno, J.; Abás, S.; Figueras, A.; Pérez, B.; Viñals, F.; Escolano, M.C.; Perales, J.C. Dibenzylxanthines as PPEPCK-M Inhibitors for Cancer Therapy. Proceedings 2019, 22, 79.

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