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Open AccessExtended Abstract

Dibenzylxanthines as PPEPCK-M Inhibitors for Cancer Therapy

Department of Physiological Sciences, Faculty of Medicine, University of Barcelona, 08907 L’Hospitalet de Llobregat, Spain
Department of Pharmacology and Medicinal Chemistry, Faculty of Pharmacy, and Institute of Biomedicine (IBUB), University of Barcelona, 08028 Barcelona, Spain
Institut D'Investigació Biomèdica de Bellvitge (IDIBELL), 08907 L’Hospitalet de Llobregat, Spain
Farmacologia Terapèutica i Toxicologia, Universitat Autònoma de Barcelona, 08193 Bellaterra, Spain
Author to whom correspondence should be addressed.
Presented at the 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15–17 May 2019.
Proceedings 2019, 22(1), 79;
Published: 16 August 2019
(This article belongs to the Proceedings of The Molecules Medicinal Chemistry Symposium)
Note: In lieu of an abstract, this is an excerpt from the first page.

Phosphoenolpyruvate carboxykinase (PEPCK) is the key enzyme in gluconeogenesis/glyceroneogenesis, which catalyzes the decarboxylation of oxaloacetate to phosphoenolpyruvate. [...]
MDPI and ACS Style

Aragó, M.; Rodríguez-Arévalo, S.; Hyrossova, P.; Moreno, J.; Abás, S.; Figueras, A.; Pérez, B.; Viñals, F.; Escolano, M.C.; Perales, J.C. Dibenzylxanthines as PPEPCK-M Inhibitors for Cancer Therapy. Proceedings 2019, 22, 79.

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