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Searching for Selective Scaffolds against Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase 6-Phosphogluconolactonase

1
Department of Nutrition, Food Science and Gastronomy, Faculty of Pharmacy and Food Sciences, Institute of Biomedicine (IBUB) and Institute of Theoretical and Computational Chemistry (ITQCUB), University of Barcelona, Av. Prat de la Riba 171, 08921 Santa Coloma de Gramenet, Spain
2
Pharmacelera, Plaça Pau Vila, 1, Sector C 2a, Edifici Palau de Mar, 08039 Barcelona, Spain
3
Department of Biochemistry and Molecular Biology, Universidad Complutense de Madrid, Facultad de Veterinaria, Ciudad Universitaria, 28040 Madrid, Spain
4
Research Institute Hospital 12 de Octubre, Avda. de Cordoba s/n, 28041 Madrid, Spain
*
Author to whom correspondence should be addressed.
Presented at the 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15–17 May 2019.
Proceedings 2019, 22(1), 28; https://doi.org/10.3390/proceedings2019022028
Published: 7 August 2019
(This article belongs to the Proceedings of The Molecules Medicinal Chemistry Symposium)
PDF [172 KB, uploaded 7 August 2019]
Note: In lieu of an abstract, this is an excerpt from the first page.

Excerpt

Malaria is a parasitic disease caused by Plasmodium spp., being one of the major causes of death worldwide with two-hundred million new infections and hundreds of thousands of deaths in 2015. [...]
Keywords: Malaria; Plasmodium falciparum; Glucose-6-Phosphate Dehydrogenase 6-Phosphogluconolactonase Malaria; Plasmodium falciparum; Glucose-6-Phosphate Dehydrogenase 6-Phosphogluconolactonase
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Viayna, A.; Vílchez, D.; Vázquez, J.; Pérez-Benavente, S.; Bautista, J.M.; Luque, F.J. Searching for Selective Scaffolds against Plasmodium falciparum Glucose-6-Phosphate Dehydrogenase 6-Phosphogluconolactonase. Proceedings 2019, 22, 28.

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