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Open AccessAbstract

Potent and Selective Estrogen Receptor-Beta Agonists Which Enhance Memory Consolidation in an Ovariectomized Mouse Model

1
Department of Pharmaceutical Sciences, Concordia University Wisconsin, Mequon, WI 53097, USA
2
Department of Chemistry, Marquette University, Milwaukee, WI 53201-1881, USA
3
Department of Psychology, University of Wisconsin-Milwaukee, Milwaukee, WI 53211, USA
4
Department of Natural Sciences, Concordia University Wisconsin, Mequon, WI 53097, USA
5
Department of Pathology, Medical College of Wisconsin, Milwaukee, WI 53226, USA
*
Author to whom correspondence should be addressed.
Presented at the 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15–17 May 2019.
Presented at the 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15–17 May 2019.
Proceedings 2019, 22(1), 73; https://doi.org/10.3390/proceedings2019022073
Published: 15 August 2019
(This article belongs to the Proceedings of The Molecules Medicinal Chemistry Symposium)
PDF [133 KB, uploaded 15 August 2019]
Note: In lieu of an abstract, this is an excerpt from the first page.

Excerpt

Estrogen receptor-beta (ER-beta) is a drug target for memory consolidation in postmenopausal [...]
Keywords: estrogen receptor agonist; SERBAs; memory consolidation; menopause; drug development estrogen receptor agonist; SERBAs; memory consolidation; menopause; drug development
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Hanson, A.M.; Perera, I.S.; Kim, J.; Sweeney, N.; Imhoff, A.; Wargolet, A.J.; Hart, R.M.V.; Mackinnon, A.C.; Frick, K.M.; Sem, D.S.; Donaldson, W.A. Potent and Selective Estrogen Receptor-Beta Agonists Which Enhance Memory Consolidation in an Ovariectomized Mouse Model. Proceedings 2019, 22, 73.

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