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Open AccessExtended Abstract

Peptidomimetic 1-Benzyl-5-methyl-4-(n-octylamino)pyrimidin-2(1H)-one Showed Cardioprotection Effect in a Myocardial Ischemia (MI) Mouse Model

1
Department of Chemistry, Faculty of Exact Sciences, Bar-Ilan University, Ramat Gan 5290002, Israel
2
Cardiac Research Laboratory, Felsenstein Research Center, Rabin Medical Center, Sackler Faculty of Medicine, Tel Aviv University, Petah Tikva 4910002, Israel
3
The Skin Research Institute, The Dead-Sea and Arava Science Center, Masada 86910, Israel
4
Department of Biopharmacy, Medical University of Lublin, 20-093 Lublin, Poland
5
Faculty of Life Sciences, Bar-Ilan University, Ramat Gan 5290002, Israel
*
Author to whom correspondence should be addressed.
Proceedings 2019, 22(1), 72; https://doi.org/10.3390/proceedings2019022072
Published: 14 August 2019
(This article belongs to the Proceedings of The Molecules Medicinal Chemistry Symposium)
Note: In lieu of an abstract, this is an excerpt from the first page.

TLR4, a member of the toll-like receptors (TLRs) family, serves as a pattern recognition receptor in the innate immune response to different microbial pathogens. [...]
Keywords: peptidomimetics; cardioprotection; in silico modeling peptidomimetics; cardioprotection; in silico modeling
MDPI and ACS Style

Trifonov, L.; Nudelman, V.; Zhenin, M.; Cohen, G.; Jozwiak, K.; Korshin, E.; Senderowitz, H.; Shainberg, A.; Hochhauser, E.; Gruzman, A. Peptidomimetic 1-Benzyl-5-methyl-4-(n-octylamino)pyrimidin-2(1H)-one Showed Cardioprotection Effect in a Myocardial Ischemia (MI) Mouse Model. Proceedings 2019, 22, 72.

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