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Open AccessExtended Abstract

Novel Sortase A Inhibitors to Counteract Gram-Positive Bacterial Biofilms

1
Department of Biological, Chemical and Pharmaceutical Sciences and Technologies, (STEBICEF), University of Palermo, via Archirafi 32, 90123 Palermo, Italy
2
Drug Sciences Department, Medicinal Chemistry and Pharmaceutical Technology Section, University of Pavia, via Taramelli 12, 27100 Pavia, Italy
3
APP Latvian Biomedical Research and Study Centre (BMC), Rātsupītes iela 1, LV-1067 Rīga, Latvia
*
Author to whom correspondence should be addressed.
Presented at the 2nd Molecules Medicinal Chemistry Symposium (MMCS): Facing Novel Challenges in Drug Discovery, Barcelona, Spain, 15–17 May 2019.
Proceedings 2019, 22(1), 23; https://doi.org/10.3390/proceedings2019022023
Published: 7 August 2019
(This article belongs to the Proceedings of The Molecules Medicinal Chemistry Symposium)
PDF [185 KB, uploaded 7 August 2019]
Note: In lieu of an abstract, this is an excerpt from the first page.

Excerpt

Sortase A (SrtA) is a membrane enzyme responsible for the covalent anchoring of surface proteins on the cell wall of Gram-positive bacteria. [...]
This is an open access article distributed under the Creative Commons Attribution License which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited (CC BY 4.0).
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Raimondi, M.V.; Listro, R.; Cusimano, M.G.; Franca, M.L.; Faddetta, T.; Gallo, G.; Schillaci, D.; Collina, S.; Leonchiks, A.; Barone, G. Novel Sortase A Inhibitors to Counteract Gram-Positive Bacterial Biofilms. Proceedings 2019, 22, 23.

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