2026 September - 139 articles
Core parameters of the Musculoskeletal Ultrasound Computed Tomography System (MUCTS), such as spatial resolution, slice thickness, and three-dimensional reconstruction volume error, directly determine imaging performance and clinical diagnostic accur...
Magnesium ions (Mg2+) play pivotal roles in bone regeneration by regulating the biological functions of multiple bone repair-related cells. However, the effective concentration ranges and optimal concentration of Mg2+ for different cell types remain...
Machine-learning gait studies often report high accuracy for separating neurodegenerative diseases, but rarely test whether this reflects pathology or the demographic differences that accompany disease in convenience cohorts. We audited the PhysioNet...
Anastomotic angle and flow allocation change together in end-to-side junctions, complicating interpretation of angle-dependent wall shear. We used MITOS Flow Lab, a two-dimensional D2Q9 two-relaxation-time lattice-Boltzmann environment, to examine th...
Glaucoma requires continuous surveillance, sustained treatment adherence, and timely recognition of postoperative or treatment-related complications. Conventional outpatient follow-up provides structured clinical assessment but offers limited visibil...
The arteriovenous fistula (AVF) is the preferred method of vascular access for hemodialysis; however, 30–50% of AVFs undergo primary maturation failure and are unsuitable for clinical use. As disturbed hemodynamics initiate endothelial injury a...
Fragility fracture and osteoporotic bone loss represent an increasing global burden in ageing populations: the Global Burden of Disease Study 2021 estimated 172.79 million new fractures, 453.31 million prevalent cases, and 25.18 million years lived w...
Dental injection needle integrity may influence tissue trauma during local anesthesia. This study compared needle-tip microstructural deformation after different local anesthesia techniques using field emission scanning electron microscopy (FESEM). A...
Extracellular vesicles (EVs) have emerged as promising cell-free therapeutic agents for bone regeneration due to their ability to modulate osteogenesis, angiogenesis, and immune responses. This review summarizes the current knowledge on EV biology, i...
(1) Background: Laser in situ fenestration (L-ISF) is an endovascular technique used to preserve target vessel patency in urgent or emergency endovascular aortic repair when fenestrated/branched solutions are unavailable or unsuitable, or as a bailou...
Accurate preoperative discrimination between indolent and aggressive renal lesions is essential for personalized risk-stratified management and improves the clinical outcomes of renal tumor patients. This study aimed to establish and externally valid...
Depression among students has emerged as a critical issue within educational institutions, leading to the need for approaches that can support early identification of students at risk. This study developed an explainable machine learning framework fo...
Cardiovascular disease diagnosis requires accurate and timely analysis of electrocardiogram (ECG) signals to support reliable clinical decision-making. However, ECG signals are inherently non-stationary, exhibit substantial inter-patient variability,...
Time-dependent force reduction may affect the biomechanical performance of thermoformed clear aligners. This proof-of-concept in vitro study compared initial and 7-day system-level 3D resultant forces of DURAN, ZENDURA FLX, and MESHEET under attachme...
Individuals undergoing anterior cruciate ligament reconstruction (ACLR) remain at risk of secondary injury and joint degeneration, highlighting the need for functional assessments that detect abnormal load regulation and compensatory movement strateg...
Ultrasound assessment of developmental dysplasia of the hip (DDH) in infants is highly operator-dependent, particularly during standard plane acquisition and Graf angle measurement. This paper proposes DDH-Net, a fully automated computer-aided assess...
Breast-conserving surgery (BCS) requires accurate intraoperative localization of the tumor, which moves between the prone diagnostic and supine surgical positions. We present a projector-based augmented-reality (AR) localization system that projects...
Background: Chronic wounds that fail to heal despite debridement and advanced care are an unmet clinical need, particularly in elderly patients and those with peripheral arterial disease, for whom the alternatives are often indefinite maintenance or...
The interaction of chemicals, nanoparticles, and circulating cells with the endothelium depends on the magnitude of the mechanical shear produced by the flow of blood. When simulating those interactions with microphysiological systems (MPSs), it is c...
Stromal keratophakia was first introduced by Jose Ignacio Barraquer in the 1960s as a refractive procedure involving the implantation of a stromal lenticule into a lamellar keratectomy bed of a recipient cornea. By increasing central corneal thicknes...
Piezo1 is an increasingly recognised mechanosensitive ion channel that transduces mechanical forces into electrical and biochemical signals and is expressed in peripheral sensory pathways as well as across multiple cell types within the central nervo...
Predictive analytics has emerged as an important component of hospital automation by enabling proactive resource management and data-driven decision-making. Efficient allocation of patient monitors in operating rooms represents a practical applicatio...
The incorporation of Digital Twins (DT) into the healthcare industry marks a revolution in terms of adopting a more proactive and personalized approach towards patient care. The increasing complexity of technological tools employed within the healthc...
Full-waveform inversion (FWI) typically employs finite-difference time-domain (FDTD) methods to solve the wave equation under the point-source assumption. For computational efficiency, the coarsest grid that satisfies dispersion and stability require...
Background: Low back pain (LBP) remains the leading global cause of years lived with disability, and image-guided nerve blocks occupy a central position in its diagnostic and therapeutic pathway. Two paraspinal targets separated by only a few centime...
Background: Implant-prosthetic rehabilitation of single-tooth edentulism often requires orthodontic reshaping of the potential implant-prosthetic space because its dimensions change due to the migration of adjacent teeth. In this context, it is very...
Chronic low back pain (CLBP) is a leading cause of disability and is characterized by marked clinical heterogeneity. Structural imaging remains fundamental for diagnosis and treatment planning, yet anatomical abnormalities alone do not fully explain...
Maxillary expansion combines sutural skeletal displacement with variable alveolar, dental, and periodontal responses. Because these effects are often reported as a single transverse outcome, their biological contributions are difficult to separate. W...
This study aimed to compare the accuracy of video-based kinematic measurements using artificial intelligence (AI) between patients with hip osteoarthritis (OA) and healthy participants, and to compare the gait abnormality estimated from video data wi...
Background: Chronic disease management, an ageing global population, and the aftermath of the COVID-19 pandemic have pushed real-time, continuous health monitoring from a research curiosity toward routine clinical practice. Artificial intelligence (A...
Extrusion-based bioprinting is governed by coupled material, extrusion, and motion parameters, yet printability is often assessed using isolated rheological tests or qualitative geometric inspection. This study developed a systems-engineering framewo...
The discoid meniscus is a morphologic variant associated with altered biomechanics and an increased risk of tearing, yet the systems used to classify it have historically emphasized shape over function. This review examines how classification of the...
Human induced pluripotent stem cells (hiPSCs) have revolutionized cardiovascular research by providing a renewable source of patient-specific cardiomyocytes for disease modeling, drug discovery, precision medicine, and regenerative therapies. Tempora...
Background: Nickel–titanium (Ni-Ti) instruments are continuously exposed to irrigating solutions during root canal preparation, which may affect their surface integrity. Evidence regarding the combined morphological and elemental effects of con...
Allergic eye disease (AED), including allergic conjunctivitis, is a prevalent immune-mediated disorder of the ocular surface characterized by itching, redness, tearing, and ocular discomfort. Although olopatadine (OLO) is widely used as an antihistam...
Background: Our objective was to evaluate the clinical effects on walking function and symmetry of combined knee-powered exoskeleton-assisted gait training (EAGT) and conventional physiotherapy versus conventional therapy alone in patients with subac...
Introduction: Voice-based digital biomarkers have emerged as a promising, non-invasive approach for the early detection and monitoring of neurodegenerative disorders, particularly Parkinson’s disease (PD). Although voice recordings can be acqui...
Background: The purpose of this in vitro study was to evaluate the fracture resistance of maxillary molar zirconia crowns cemented with deep margins relocated with resin composite. Methods: A maxillary right first-molar typodont tooth was prepared fo...
Pancreatic ductal adenocarcinoma (PDAC) is a highly aggressive, treatment-resistant tumor requiring novel therapeutic approaches. Electroporation (EP)-based strategies are promising tools for local tumor control and enhanced drug delivery. However, c...
A brain tumor is a life-threatening disease that carries a high mortality burden. It can be treated if detected in the early stages. Manual analysis by a radiologist using Magnetic Resonance Imaging (MRI) is effective but slow and subject to inter-ob...
Transcranial magnetic stimulation (TMS) enables non-invasive, focal modulation of cortical circuits by inducing electric currents in the brain through electromagnetic induction, thereby influencing neuronal excitability and synaptic plasticity. High...
Adenosine is a ubiquitous stress marker and is characterised by numerous vital functions in all organs. Although adenosine has been investigated for decades, the information about its metabolism in islet cells has mainly been obtained in rodents. The...
Dental rehabilitation of fibula free flap mandibular reconstructions can be limited by the reduced vertical bone height available for implant placement. This study evaluated the biomechanical influence of ultra-short, extra-short, and conventional im...
Urethral reconstruction is required for a variety of congenital and acquired conditions. Current grafting techniques rely on autologous tissues such as buccal mucosa, which are often limited by donor-site morbidity. Biomaterials could be an alternati...
The insular cortex, especially its posterior subdivision, is a key hub for interoceptive, somatosensory, and nociceptive processing, making it a compelling target for neuromodulation. However, its depth within the lateral sulcus makes it difficult to...
Three-dimensionally (3D)-printed alpha-tricalcium phosphate (α-TCP) scaffolds, fabricated through a low-temperature hydrothermal dissolution-precipitation process, replicate the structural and compositional features of native bone. Reinforcing...
Halo-gravity traction (HGT) is widely used as a preoperative treatment for severe pediatric spinal deformities by gradually applying traction forces through a cranial fixation system. Although the clinical effectiveness of HGT has been extensively do...
Medical adhesives have been extensively applied for skin wound repair and hemostasis, while the dynamically humid and complex intraperitoneal environment imposes stringent requirements on tissue adhesives. Few studies have reported the application of...
Knee osteoarthritis (OA) has long been viewed as a cartilage-centered disease, but a whole-joint model now positions the subchondral bone and the osteochondral unit as biologically active, mechanically decisive participants. Bone marrow lesions (BMLs...
Myofascial pain syndrome (MPS) of the cervicoscapular girdle—most typically involving the upper trapezius and the rhomboid muscles—is among the most frequent causes of chronic regional musculoskeletal pain, yet the mainstays of interventi...
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