Low-Back Pain: Assessment and Rehabilitation Research

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 31 January 2026 | Viewed by 1537

Special Issue Editors

Special Issue Information

Dear Colleagues,

Low-back pain (LBP) remains one of the most prevalent and disabling musculoskeletal conditions globally, contributing significantly to years lived with disability and imposing a substantial socioeconomic burden. Despite extensive research, the complexity of its pathophysiology, ranging from mechanical and neurogenic factors to psychosocial influences, continues to challenge both diagnostic accuracy and treatment efficacy. In recent years, advances in bioengineering have opened new avenues for the assessment and rehabilitation of LBP, including wearable technologies, sensor-based functional assessments, computational modeling, and neuromechanical interventions.

This Special Issue of Bioengineering aims to bring together original research articles, systematic reviews, and methodological advances focusing on innovative tools, technologies, and approaches for evaluating and rehabilitating LBP patients. Emphasis is placed on the integration of biomechanical analysis, imaging, machine learning algorithms, and assistive devices into clinical practice. Submissions exploring translational research and interdisciplinary strategies that enhance diagnostic precision, personalize rehabilitation protocols, or improve patient outcomes are especially encouraged.

By fostering collaboration across engineering, clinical, and rehabilitation sciences, this Special Issue seeks to promote a comprehensive understanding of LBP and support the development of evidence-based, technology-driven solutions for its management. Researchers, clinicians, and innovators are invited to contribute to this evolving field.

We look forward to receiving your contributions.

Prof. Dr. Giustino Varrassi
Dr. Giacomo Farì
Guest Editors

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Keywords

  • chronic pain
  • wearable technologies
  • computational modeling
  • biomechanical analysis
  • assistive devices
  • sensor-based functional assessments

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Published Papers (1 paper)

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28 pages, 1314 KB  
Systematic Review
Bioengineering Support in the Assessment and Rehabilitation of Low Back Pain
by Giustino Varrassi, Matteo Luigi Giuseppe Leoni, Ameen Abdulhasan Al-Alwany, Piercarlo Sarzi Puttini and Giacomo Farì
Bioengineering 2025, 12(9), 900; https://doi.org/10.3390/bioengineering12090900 - 22 Aug 2025
Viewed by 672
Abstract
Low back pain (LBP) remains one of the most prevalent and disabling musculoskeletal conditions globally, with profound social, economic, and healthcare implications. The rising incidence and chronic nature of LBP highlight the need for more objective, personalized, and effective approaches to assessment and [...] Read more.
Low back pain (LBP) remains one of the most prevalent and disabling musculoskeletal conditions globally, with profound social, economic, and healthcare implications. The rising incidence and chronic nature of LBP highlight the need for more objective, personalized, and effective approaches to assessment and rehabilitation. In this context, bioengineering has emerged as a transformative field, offering novel tools and methodologies that enhance the understanding and management of LBP. This narrative review examines current bioengineering applications in both diagnostic and therapeutic domains. For assessment, technologies such as wearable inertial sensors, three-dimensional motion capture systems, surface electromyography, and biomechanical modeling provide real-time, quantitative insights into posture, movement patterns, and muscle activity. On the therapeutic front, innovations including robotic exoskeletons, neuromuscular electrical stimulation, virtual reality-based rehabilitation, and tele-rehabilitation platforms are increasingly being integrated into multimodal treatment protocols. These technologies support precision medicine by tailoring interventions to each patient’s biomechanical and functional profile. Furthermore, the incorporation of artificial intelligence into clinical workflows enables automated data analysis, predictive modeling, and decision support systems, while future directions such as digital twin technology hold promise for personalized simulation and outcome forecasting. While these advancements are promising, further validation in large-scale, real-world settings is required to ensure safety, efficacy, and equitable accessibility. Ultimately, bioengineering provides a multidimensional, data-driven framework that has the potential to significantly improve the assessment, rehabilitation, and overall management of LBP. Full article
(This article belongs to the Special Issue Low-Back Pain: Assessment and Rehabilitation Research)
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