Advanced Biomaterials for Bone Regeneration and Remodeling

Dear Colleagues,

This Special Issue, titled “Advanced Biomaterials for Bone Regeneration and Remodeling”, will focus on the integration of regeneration and remodeling (dynamic, long-term bone adaptation), with emphasis on translation from bench to clinic and complex clinical microenvironments (aging, inflammation, infection, oncology).

The main topics include the development of personalized bone tissue engineering scaffolds (including microfluidics and bioink optimization), biomaterial-mediated vascularized bone regeneration, biomaterials regulating bone remodeling through osteoimmunomodulation, mechanotransduction, and controlled degradation. In addition, research on innovative fabrication methods for bone repair biomaterials/tissue engineering scaffolds are highly encouraged, such as smart/responsive biomaterials, injectable and minimally invasive systems, gene-activated and cell-free biomaterials, and AI-assisted or data-driven biomaterial design. Studies that address translational challenges, including preclinical validation, regulatory considerations, and scalable manufacturing, are highly encouraged.

Sincerely,

Dr. Cairong Li
Guest Editor

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