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Bioengineering
Special Issues
Contemporary Trends and Future Perspectives in Orthodontic Treatment
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Contemporary Trends and Future Perspectives in Orthodontic Treatment

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Biomedical Engineering and Biomaterials".

Deadline for manuscript submissions: 31 March 2026 | Viewed by 45

Special Issue Editors

Dr. Simone Parrini

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Guest Editor
Department of Orthodontics, Dental School, University of Turin, 10126 Turin, Italy
Interests: clear aligner; orthodontic; esthetics; finite element analysis
Special Issues, Collections and Topics in MDPI journals
Dr. Gabriele Rossini

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Guest Editor
Department of Orthodontics, Dental School, University of Turin, 10126 Turin, Italy
Interests: clear aligner; orthodontic; esthetics; finite element analysis
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

The field of orthodontics is experiencing a dynamic evolution, with emerging technologies and evidence-based strategies reshaping both clinical practice and research. This Special Issue aims to provide a comprehensive overview of the current state of orthodontic treatment and to explore the innovations that are defining its future.

We welcome original research articles, clinical studies, and reviews that address recent advances in orthodontic biomechanics, clear aligner therapy, and digital workflows. Topics of interest include, but are not limited to, the predictive modeling of tooth movement, treatment planning with artificial intelligence, integration of 3D imaging and finite element analysis, and the development of novel materials and appliances. Contributions focusing on long-term stability, patient-centered outcomes, and interdisciplinary treatment approaches are also encouraged.

By bringing together diverse perspectives and methodologies, this Special Issue seeks to foster dialogue within the orthodontic community and to promote high-quality, forward-thinking research that can guide future clinical decision-making.

We look forward to your valuable contributions.

Dr. Simone Parrini
Dr. Gabriele Rossini
Guest Editors

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • orthodontic biomechanics
  • clear aligners
  • digital orthodontics
  • artificial intelligence
  • finite element analysis
  • interdisciplinary treatment
  • patient experience
  • long-term stability
  • innovative appliances
  • future trends in orthodontics

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Published Papers (1 paper)

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Research

17 pages, 3785 KiB  
Article
The Role of Stable Anatomical Landmarks in Automated 3D Model Superimposition: A Closer Look
by Tommaso Castroflorio, Samuele Avolese, Fabrizio Sanna and Simone Parrini
Bioengineering 2025, 12(8), 839; https://doi.org/10.3390/bioengineering12080839 (registering DOI) - 3 Aug 2025
Abstract
Objective: To evaluate the concordance of automated 3D superimposition methods applied to digital models, with a focus on methods that consider stable palatal regions as geometric reference landmarks versus those that do not. Design and setting: This was a prospective, cross-sectional study using [...] Read more.
Objective: To evaluate the concordance of automated 3D superimposition methods applied to digital models, with a focus on methods that consider stable palatal regions as geometric reference landmarks versus those that do not. Design and setting: This was a prospective, cross-sectional study using digital model files of patients undergoing orthodontic treatment in a university clinical setting. Participants: Sixty-one patients were prospectively enrolled and divided into three groups based on the type of orthodontic treatment they received: (20) non-extractive orthodontic treatment without intermaxillary elastics, (21) intermaxillary elastics, and (20) control subjects with no orthodontic movement. The inclusion criteria included the availability of complete pre- and post-treatment digital casts and the absence of significant craniofacial anomalies. Methods: Three superimposition methods were tested: (1) superimposition according to palate and palatal ridges, (2) best-fit superimposition of arches in occlusion, and (3) best-fit superimposition of individual arches. Discrepancies were identified by comparing the spatial positions derived from each method. Within three spatial axes, deviations of ±0.5 mm and ±1.15° were not considered significant. Bland–Altman plots were used to quantify palatal rugae based and non-based spatial differences between methods. Differences in the superimposition results between the three patient groups were evaluated using ANOVA tests. Results: Differences in spatial position between the superimposition methods often exceeded the acceptable range. The results were compared between the three patient groups with a statistical significance of α = 0.05. In the present study, the high reliability of the superimposition method based on the palate and palatal ridges was observed. Conclusion: Superimposition methods based on the palate and palatal rugae provide superior accuracy in determining treatment-related changes in upper arch digital models. These findings illustrate the need for appropriate selection of superimposition techniques based on the study objective of using clinically relevant techniques. Full article
(This article belongs to the Special Issue Contemporary Trends and Future Perspectives in Orthodontic Treatment)
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