Hard Tissue Engineering and 3D Bioprinting

A special issue of Bioengineering (ISSN 2306-5354). This special issue belongs to the section "Nanobiotechnology and Biofabrication".

Deadline for manuscript submissions: 31 August 2026 | Viewed by 99

Special Issue Editor


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Guest Editor
Joint Department of Biomedical Engineering, Marquette University, Medical College of Wisconsin, Milwaukee, WI 53226, USA
Interests: nanomaterial; stem cell; tissue engineering
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Special Issue Information

Dear Colleagues,

Hard tissue engineering has emerged as a transformative approach in addressing critical clinical challenges associated with bone, cartilage, and osteochondral defects resulting from trauma, degeneration, congenital disorders, and tumor resection. Despite significant advances in biomaterials, cell biology, and regenerative medicine, achieving functional, patient-specific hard tissue regeneration remains a major unmet need. Recent progress in 3D bioprinting has opened up unprecedented opportunities to precisely engineer complex hard tissue constructs with controlled architecture, mechanical properties, spatial cell organization, and bioactive cue presentation.

This Special Issue, “Hard Tissue Engineering and 3D Bioprinting”, will highlight cutting-edge research that integrates advanced biomaterials, biofabrication technologies, and biological strategies to restore hard tissue structure and function. Topics of interest include, but are not limited to, printable biomaterials and bioinks, vascularized and multi-tissue constructs, cell-free and cell-laden bioprinting strategies, biomimetic scaffold design, in situ bioprinting, and translational and preclinical studies. Computational modeling, imaging-guided design, and emerging manufacturing approaches that enhance scalability and clinical relevance are also within the scope.

By bringing together interdisciplinary contributions from engineering, materials science, biology, and clinical research, this Special Issue will provide a comprehensive overview of current advances, identify remaining challenges, and outline future directions for the translation of hard tissue engineering and 3D bioprinting technologies to clinical application.

Dr. Bo Wang
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 250 words) can be sent to the Editorial Office for assessment.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Bioengineering is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • hard tissue engineering
  • 3D bioprinting
  • biofabrication
  • biomimetic scaffolds
  • regenerative medicine

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Published Papers

This special issue is now open for submission.
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