Biomolecules, Volume 16, Issue 1
2026 January - 179 articles
Cover Story: Gal-10 is considered an effective biomarker of eosinophilic and type-2 inflammation and a potential therapeutic target. However, the extracellular crystallization of this protein and its role in the progression of nasal inflammation and mucosa remodeling are not fully understood. The aim of the present study was to evaluate the potential role of Gal-10 in driving nasal mucosa inflammation, epithelial dysfunction, and remodeling in patients with seasonal allergic rhinitis (SAR). Our results indicate that Gal-10 is associated with Th2-type inflammation, mucus overproduction, and epithelial–mesenchymal transition (EMT)-related signaling in the nasal mucosa of children with SAR, potentially predisposing them to structural airway dysfunction and progression of respiratory diseases. View this paper
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Biomolecules - ISSN 2218-273X