Pathogenesis and Targeted Therapy of Neurodegenerative Diseases

Dear Colleagues, 

Neurodegenerative diseases, such as Alzheimer’s disease, Parkinson’s disease, Huntington’s disease, and amyotrophic lateral sclerosis (ALS), represent a growing global health concern due to their increasing prevalence and lack of curative treatments. These disorders are characterized by a progressive loss of neurons and synaptic function, leading to debilitating cognitive and motor impairments. Recent advances in molecular neuroscience have uncovered critical mechanisms underlying disease pathogenesis, including protein misfolding, mitochondrial dysfunction, oxidative stress, and neuroinflammation. Understanding these pathways opens the door to the development of targeted therapies that aim not only to alleviate symptoms but also to modify disease progression. This Special Issue invites original research articles, reviews, and perspectives that explore the molecular mechanisms of neurodegeneration and innovative therapeutic strategies. Contributions highlighting novel biomarkers, emerging therapeutic targets, or translational approaches are particularly encouraged.

Dr. Wioletta Rozpędek-Kamińska
Guest Editor

Manuscript Submission Information

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Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Biomolecules is an international peer-reviewed open access monthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2700 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.