You are currently on the new version of our website. Access the old version .

Metabolites, Volume 13, Issue 8

August 2023 - 85 articles

Cover Story: Adolescents obesity is a global concern. We used untargeted metabolomics to study the metabolic consequences of BMI changes in male adolescents. Urine samples from 360 participants were analyzed using UPLC-QTOF-MS. Significant metabolic features were identified in the discovery and validation sets. Metabolites such as glycylproline and citrulline were associated with BMI. Histidine and arginine metabolism were affected pathways. Our findings indicate that obesity and its metabolic outcomes are associated with altered amino acids, lipid, and carbohydrate metabolism in urine. These metabolites could serve as biomarkers for obesity. Further research is needed to understand their role in obesity development. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (85)

  • Article
  • Open Access
12 Citations
4,741 Views
20 Pages

Liver Metabolomics and Inflammatory Profiles in Mouse Model of Fentanyl Overdose Treated with Beta-Lactams

  • Fawaz Alasmari,
  • Mohammed S. Alasmari,
  • Mohammed A. Assiri,
  • Mohammed Alswayyed,
  • Syed Rizwan Ahamad,
  • Abdulrahman I. Alhumaydhi,
  • Bandar I. Arif,
  • Sahar R. Aljumayi,
  • Abdullah F. AlAsmari and
  • Youssef Sari
  • + 2 authors

21 August 2023

Fentanyl is a highly potent opioid analgesic that is approved medically to treat acute and chronic pain. There is a high potential for overdose-induced organ toxicities, including liver toxicity, and this might be due to the increase of recreational...

  • Article
  • Open Access
9 Citations
2,500 Views
15 Pages

Faba Bean (Vicia faba L. minor) Bitterness: An Untargeted Metabolomic Approach to Highlight the Impact of the Non-Volatile Fraction

  • Adeline Karolkowski,
  • Emmanuelle Meudec,
  • Antoine Bruguière,
  • Anne-Claire Mitaine-Offer,
  • Emilie Bouzidi,
  • Loïc Levavasseur,
  • Nicolas Sommerer,
  • Loïc Briand and
  • Christian Salles

21 August 2023

In the context of climate change, faba beans are an interesting alternative to animal proteins but are characterised by off-notes and bitterness that decrease consumer acceptability. However, research on pulse bitterness is often limited to soybeans...

  • Article
  • Open Access
8 Citations
2,179 Views
16 Pages

20 August 2023

Approximately 25% of psoriasis patients have an inflammatory arthritis termed psoriatic arthritis (PsA). There is strong interest in identifying and validating biomarkers that can accurately and reliably predict conversion from psoriasis to PsA using...

  • Technical Note
  • Open Access
1 Citations
2,710 Views
9 Pages

19 August 2023

Gas chromatography–mass spectrometry (GC-MS) usually employs hard electron ionization, leading to extensive fragmentations that are suitable to identify compounds based on library matches. However, such spectra are less useful to structurally c...

  • Article
  • Open Access
5 Citations
2,143 Views
17 Pages

The Urine Metabolome of R6/2 and zQ175DN Huntington’s Disease Mouse Models

  • Roberto Speziale,
  • Camilla Montesano,
  • Giulia Di Pietro,
  • Daniel Oscar Cicero,
  • Vincenzo Summa,
  • Edith Monteagudo and
  • Laura Orsatti

18 August 2023

Huntington’s disease (HD) is caused by the expansion of a polyglutamine (polyQ)-encoding tract in exon 1 of the huntingtin gene to greater than 35 CAG repeats. It typically has a disease course lasting 15–20 years, and there are currently...

  • Article
  • Open Access
8 Citations
2,042 Views
13 Pages

18 August 2023

Age-related hepatic lipid accumulation has become a major health problem in the elderly population. Specnuezhenide (SPN) is a major active iridoid glycoside from an edible herb Fructus Ligustri Lucidi, which is commonly used for preventing age-relate...

  • Article
  • Open Access
7 Citations
2,888 Views
12 Pages

Plasma Amino Acids in NAFLD Patients with Obesity Are Associated with Steatosis and Fibrosis: Results from the MAST4HEALTH Study

  • Athina I. Amanatidou,
  • Eleni V. Mikropoulou,
  • Charalampia Amerikanou,
  • Maja Milanovic,
  • Stefan Stojanoski,
  • Mladen Bjelan,
  • Lucia Cesarini,
  • Jonica Campolo,
  • Anastasia Thanopoulou and
  • on behalf of the Mast4Health consortium
  • + 9 authors

18 August 2023

Non-alcoholic fatty liver disease (NAFLD) and non-alcoholic steatohepatitis (NASH) have been linked to changes in amino acid (AA) levels. The objective of the current study was to examine the relationship between MRI parameters that reflect inflammat...

  • Article
  • Open Access
16 Citations
7,244 Views
14 Pages

18 August 2023

Luria–Bertani broth (LB) culture medium is a commonly used bacterial culture medium in the laboratory. The nutrient composition, concentration, and culture conditions of LB medium can influence the growth of microbial strains. The purpose of th...

  • Article
  • Open Access
15 Citations
4,843 Views
16 Pages

Influence of Heat Stress on Body Temperatures Measured by Infrared Thermography, Blood Metabolic Parameters and Its Correlation in Sheep

  • Aleksandar Čukić,
  • Simeon Rakonjac,
  • Radojica Djoković,
  • Marko Cincović,
  • Snežana Bogosavljević-Bošković,
  • Milun Petrović,
  • Željko Savić,
  • Ljiljana Andjušić and
  • Biljana Andjelić

18 August 2023

The aim of this research is to examine the influence of heat stress (HS) on body temperature (BT) measured rectally (RT) or by infrared thermography (IRT) of the nose (NT), eye (ET), leg (LT) and abdominal (AT) regions in intensively and extensively...

  • Article
  • Open Access
2,105 Views
10 Pages

Metabolic Syndrome in Affective Disorders: Associations with Dark Triad Personality Traits

  • Fiona Brugger,
  • Elena M. D. Schönthaler,
  • Andreas Baranyi,
  • Eva Z. Reininghaus,
  • Dirk von Lewinski and
  • Nina Dalkner

18 August 2023

Previous research has focused on the relationship between affective disorders (AD) and metabolic syndrome (MetS). Aside from biological and lifestyle factors, personality traits were identified as influencing aspects. In particular, the Dark Triad pe...

of 9

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Metabolites - ISSN 2218-1989