Table of Contents
Coatings, Volume 9, Issue 6 (June 2019)
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Cover Story (view full-size image) Force-spinning is a versatile and low-cost alternative to electrospinning. PHBV is a microbial [...] Read more. Force-spinning is a versatile and low-cost alternative to electrospinning. PHBV is a microbial polymer with benign degradation products and can provide a suitable substrate to guide tissue regeneration, although it is limited in application by poor cellular adhesion properties. To produce extracellular matrix (ECM) mimicking fibre membranes from force-spun PHBV, we have grafted collagen molecules, with bio-functional motifs incorporated onto the fibres, enhancing the biological properties without degradation of key physical characteristics. The production rate and cytocompatibility of Collagen Functionalised Force-Spun PHBV Membranes are assessed to demonstrate that this is a quick and scalable production method for ECM-like membranes. View this paper.