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Biosensors, Volume 12, Issue 7

2022 July - 118 articles

Cover Story: In this study, the development of the first electrochemical aptasensor for the detection of 3-O-C12-HSL is reported. A carbon-based screen-printed electrode modified with gold nanoparticles proved to be the best platform for the aptasensor. Each step in the fabrication of the aptasensor (i.e., the deposition of gold nanoparticles, aptamer immobilization, and incubation with the analyte) was optimized and characterized using cyclic voltammetry, differential pulse voltammetry, and electrochemical impedance spectroscopy. Different redox probes were evaluated in the solution, with the best results being obtained in the presence of [Fe(CN)6]4−/[Fe(CN)6]3−. The binding affinity of 106.7 nM for the immobilized thiol-terminated aptamer was determined using surface plasmon resonance. View this paper
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Articles (118)

  • Article
  • Open Access
8 Citations
3,678 Views
23 Pages

21 July 2022

Many studies have explored divergent deep neural networks in human activity recognition (HAR) using a single accelerometer sensor. Multiple types of deep neural networks, such as convolutional neural networks (CNN), long short-term memory (LSTM), or...

  • Review
  • Open Access
89 Citations
10,011 Views
31 Pages

Recent Advancements in Electrochemical Biosensors for Monitoring the Water Quality

  • Yun Hui,
  • Zhaoling Huang,
  • Md Eshrat E. Alahi,
  • Anindya Nag,
  • Shilun Feng and
  • Subhas Chandra Mukhopadhyay

21 July 2022

The release of chemicals and microorganisms from various sources, such as industry, agriculture, animal farming, wastewater treatment plants, and flooding, into water systems have caused water pollution in several parts of our world, endangering aqua...

  • Review
  • Open Access
10 Citations
3,828 Views
14 Pages

Plasmonic Approaches for the Detection of SARS-CoV-2 Viral Particles

  • Sabine Szunerits,
  • Hiba Saada,
  • Quentin Pagneux and
  • Rabah Boukherroub

21 July 2022

The ongoing highly contagious Coronavirus disease 2019 (COVID-19) pandemic, caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), underlines the fundamental position of diagnostic testing in outbreak control by allowing a distinctio...

  • Review
  • Open Access
91 Citations
7,225 Views
29 Pages

21 July 2022

Aggregation-induced emission (AIE) is a unique research topic and property that can lead to a wide range of applications, including cellular imaging, theranostics, analyte quantitation and the specific detection of biologically important species. Tow...

  • Article
  • Open Access
10 Citations
3,573 Views
14 Pages

21 July 2022

Red blood cell sedimentation has been used as a promising indicator of hematological diseases and disorders. However, to address several issues (i.e., syringe installation direction, blood on-off flow control, image-based quantification, and hemodilu...

  • Article
  • Open Access
8 Citations
3,791 Views
16 Pages

A Neural Sensor with a Nanocomposite Interface for the Study of Spike Characteristics of Hippocampal Neurons under Learning Training

  • Shihong Xu,
  • Yu Deng,
  • Jinping Luo,
  • Yaoyao Liu,
  • Enhui He,
  • Yan Yang,
  • Kui Zhang,
  • Longze Sha,
  • Yuchun Dai and
  • Xinxia Cai
  • + 5 authors

21 July 2022

Both the cellular- and population-level properties of involved neurons are essential for unveiling the learning and memory functions of the brain. To give equal attention to these two aspects, neural sensors based on microelectrode arrays (MEAs) have...

  • Article
  • Open Access
18 Citations
3,495 Views
11 Pages

A Polypyrrole/Nanoclay Hybrid Film for Ultra-Sensitive Cardiac Troponin T Electrochemical Immunosensor

  • Vicente P. A. Landim,
  • Marcos V. Foguel,
  • Cecília M. Prado,
  • Maria P. T. Sotomayor,
  • Iolanda C. Vieira,
  • Bárbara V. M. Silva and
  • Rosa F. Dutra

21 July 2022

An electrochemical immunosensor based on a nanohybrid film of carboxylated polypyrrole and amine nanoclay was developed for label-free detection of the human cardiac troponin T (cTnT). The nanohybrid film was formed in situ on the surface of the glas...

  • Article
  • Open Access
15 Citations
3,781 Views
12 Pages

RhB@MOF-5 Composite Film as a Fluorescence Sensor for Detection of Chilled Pork Freshness

  • Jingyi Li,
  • Ning Zhang,
  • Xin Yang,
  • Xinting Yang,
  • Zengli Wang and
  • Huan Liu

20 July 2022

This study presents a novel composite thin film based on rhodamine B encapsulated into MOF-5 (Metal Organic Frameworks) as a fluorescence sensor for the real-time detection of the freshness of chilled pork. The composite film can adsorb and respond t...

  • Review
  • Open Access
234 Citations
24,180 Views
25 Pages

Biosensors and Microfluidic Biosensors: From Fabrication to Application

  • Madhusudan B. Kulkarni,
  • Narasimha H. Ayachit and
  • Tejraj M. Aminabhavi

20 July 2022

Biosensors are ubiquitous in a variety of disciplines, such as biochemical, electrochemical, agricultural, and biomedical areas. They can integrate various point-of-care applications, such as in the food, healthcare, environmental monitoring, water q...

  • Article
  • Open Access
35 Citations
3,967 Views
15 Pages

HCTNet: A Hybrid ConvNet-Transformer Network for Retinal Optical Coherence Tomography Image Classification

  • Zongqing Ma,
  • Qiaoxue Xie,
  • Pinxue Xie,
  • Fan Fan,
  • Xinxiao Gao and
  • Jiang Zhu

20 July 2022

Automatic and accurate optical coherence tomography (OCT) image classification is of great significance to computer-assisted diagnosis of retinal disease. In this study, we propose a hybrid ConvNet-Transformer network (HCTNet) and verify the feasibil...

  • Article
  • Open Access
14 Citations
3,213 Views
12 Pages

Millimeter Wave-Based Non-Destructive Biosensor System for Live Fish Monitoring

  • Meng Wang,
  • Yunyue Yang,
  • Boyu Mu,
  • Marina A. Nikitina and
  • Xinqing Xiao

20 July 2022

Waterless transportation for live grouper is a novel mode of transport that not only saves money, but also lowers wastewater pollution. Technical obstacles remain, however, in achieving intelligent monitoring and a greater survival rate. During live...

  • Article
  • Open Access
26 Citations
6,164 Views
18 Pages

Flexible Glassy Carbon Multielectrode Array for In Vivo Multisite Detection of Tonic and Phasic Dopamine Concentrations

  • Elisa Castagnola,
  • Elaine M. Robbins,
  • Bingchen Wu,
  • May Yoon Pwint,
  • Raghav Garg,
  • Tzahi Cohen-Karni and
  • Xinyan Tracy Cui

20 July 2022

Dopamine (DA) plays a central role in the modulation of various physiological brain functions, including learning, motivation, reward, and movement control. The DA dynamic occurs over multiple timescales, including fast phasic release, as a result of...

  • Article
  • Open Access
4 Citations
3,024 Views
12 Pages

Ultralow Laser Power Three-Dimensional Superresolution Microscopy Based on Digitally Enhanced STED

  • Xiaochun Shen,
  • Luwei Wang,
  • Wei Li,
  • He Wang,
  • Hanqiu Zhou,
  • Yinru Zhu,
  • Wei Yan and
  • Junle Qu

20 July 2022

The resolution of optical microscopes is limited by the optical diffraction limit; in particular, the axial resolution is much lower than the lateral resolution, which hinders the clear distinction of the three-dimensional (3D) structure of cells. Al...

  • Article
  • Open Access
14 Citations
3,687 Views
24 Pages

20 July 2022

Developing rapid, sensitive detection methods for 3,4-Methylenedioxymethylamphetamine (MDMA) is crucial to reduce its current misuse in the world population. With that aim, we developed an aptamer-modified tin nanoparticle (SnNP)-based nanoarchitectu...

  • Article
  • Open Access
1 Citations
3,910 Views
15 Pages

A Point-of-Care Device for Fully Automated, Fast and Sensitive Protein Quantification via qPCR

  • Francesca Romana Cavallo,
  • Khalid Baig Mirza,
  • Sara de Mateo,
  • Luca Miglietta,
  • Jesus Rodriguez-Manzano ,
  • Konstantin Nikolic and
  • Christofer Toumazou

19 July 2022

This paper presents a fully automated point-of-care device for protein quantification using short-DNA aptamers, where no manual sample preparation is needed. The device is based on our novel aptamer-based methodology combined with real-time polymeras...

  • Article
  • Open Access
15 Citations
3,669 Views
11 Pages

18 July 2022

A highly sensitive and precise Love wave mode surface acoustic wave (SAW) immunosensor based on an ST-cut 90°X quartz substrate and an SiO2 wave-guiding layer was developed to detect cancer-related biomarkers of carcinoembryonic antigens (CEAs)....

  • Article
  • Open Access
74 Citations
3,475 Views
13 Pages

Optical Detection of Fat Concentration in Milk Using MXene-Based Surface Plasmon Resonance Structure

  • Abdulkarem H. M. Almawgani,
  • Malek G. Daher,
  • Sofyan A. Taya,
  • Mohammad Mashagbeh and
  • Ilhami Colak

18 July 2022

MXene (Ti3C2Tx) has emerged very recently as an interacting material for surface plasmon resonance (SPR) configuration. It was discovered that Ti3C2Tx can facilitate the adsorption of biomolecules due to its higher binding energies, stronger interact...

  • Article
  • Open Access
9 Citations
3,988 Views
15 Pages

Design and Realization of MEMS Heart Sound Sensor with Concave, Racket-Shaped Cilium

  • Yuhua Yang,
  • Bo Wang,
  • Jiangong Cui,
  • Guojun Zhang,
  • Renxin Wang,
  • Wendong Zhang,
  • Changde He,
  • Yirui Li,
  • Pengcheng Shi and
  • Shuotong Wang

18 July 2022

The biomedical acoustic signal plays an important role in clinical non-invasive diagnosis. In view of the deficiencies in early diagnosis of cardiovascular diseases, acoustic properties of S1 and S2 heart sounds are utilized. In this paper, we propos...

  • Article
  • Open Access
14 Citations
3,976 Views
14 Pages

17 July 2022

The detection of miRNA shows great promise in disease diagnosis. In this work, a ratiometric fluorescent biosensor based on multi-walled carbon nanotubes@gold nanoclusters (MWCNTs@Au NCs) and duplex-specific nuclease (DSN)-assisted signal amplificati...

  • Review
  • Open Access
33 Citations
8,504 Views
29 Pages

16 July 2022

Bacterial contamination is a public health concern worldwide causing enormous social and economic losses. For early diagnosis and adequate management to prevent or treat pathogen-related illnesses, extensive effort has been put into the development o...

  • Article
  • Open Access
8 Citations
3,173 Views
15 Pages

15 July 2022

Currently, brucellosis seriously threatens the health of humans and animals and hinders the development of animal husbandry. However, the diagnostic methods for brucellosis have some disadvantages, such as low sensitivity, long detection time, profes...

  • Article
  • Open Access
12 Citations
4,245 Views
14 Pages

Probing Denaturation of Protein A via Surface-Enhanced Infrared Absorption Spectroscopy

  • Valentina Di Meo,
  • Massimo Moccia,
  • Gennaro Sanità,
  • Alessio Crescitelli,
  • Annalisa Lamberti,
  • Vincenzo Galdi,
  • Ivo Rendina and
  • Emanuela Esposito

15 July 2022

We apply surface-enhanced infrared absorption (SEIRA) spectroscopy to monitor the denaturation process of a surface-bound protein A monolayer. Our proposed platform relies on a plasmonic metasurface comprising different spatial subregions (“pix...

  • Article
  • Open Access
27 Citations
4,957 Views
19 Pages

Integrated Polarization-Splitting Grating Coupler for Chip-Scale Atomic Magnetometer

  • Jinsheng Hu,
  • Jixi Lu,
  • Zihua Liang,
  • Lu Liu,
  • Weiyi Wang,
  • Peng Zhou and
  • Mao Ye

15 July 2022

Atomic magnetometers (AMs) are widely acknowledged as one of the most sensitive kind of instruments for bio-magnetic field measurement. Recently, there has been growing interest in developing chip-scale AMs through nanophotonics and current CMOS-comp...

  • Article
  • Open Access
12 Citations
2,778 Views
9 Pages

15 July 2022

Target-induced differences in the electrostatic interactions between methylene blue (MB) and indium tin oxide (ITO) electrode surface was firstly employed to develop a homogeneous electrochemical biosensor for flap endonuclease 1 (FEN1) detection. In...

  • Article
  • Open Access
8 Citations
3,180 Views
19 Pages

14 July 2022

Copper is an inexpensive material that has found wide application in electronics due to its remarkable electric properties. However, the high toxicity of both copper and copper oxide imposes restrictions on the application of this metal as a material...

  • Article
  • Open Access
7 Citations
4,469 Views
18 Pages

Large Area Microfluidic Bioreactor for Production of Recombinant Protein

  • Natalia Bourguignon,
  • Paola Karp,
  • Carolina Attallah,
  • Daniel A. Chamorro,
  • Marcos Oggero,
  • Ross Booth,
  • Sol Ferrero,
  • Shekhar Bhansali,
  • Maximiliano S. Pérez and
  • Gustavo Helguera
  • + 1 author

14 July 2022

To produce innovative biopharmaceuticals, highly flexible, adaptable, robust, and affordable bioprocess platforms for bioreactors are essential. In this article, we describe the development of a large-area microfluidic bioreactor (LM bioreactor) for...

  • Article
  • Open Access
9 Citations
2,774 Views
15 Pages

Ultrasensitive Diamond Microelectrode Application in the Detection of Ca2+ Transport by AnnexinA5-Containing Nanostructured Liposomes

  • Alberto Pasquarelli,
  • Luiz Henrique Silva Andrilli,
  • Maytê Bolean,
  • Claudio Reis Ferreira,
  • Marcos Antônio Eufrásio Cruz,
  • Flavia Amadeu de Oliveira,
  • Ana Paula Ramos,
  • José Luis Millán,
  • Massimo Bottini and
  • Pietro Ciancaglini

14 July 2022

This report describes the innovative application of high sensitivity Boron-doped nanocrystalline diamond microelectrodes for tracking small changes in Ca2+ concentration due to binding to Annexin-A5 inserted into the lipid bilayer of liposomes (prote...

  • Article
  • Open Access
20 Citations
3,444 Views
18 Pages

New ECG Compression Method for Portable ECG Monitoring System Merged with Binary Convolutional Auto-Encoder and Residual Error Compensation

  • Jiguang Shi,
  • Fei Wang,
  • Moran Qin,
  • Aiyun Chen,
  • Wenhan Liu,
  • Jin He,
  • Hao Wang,
  • Sheng Chang and
  • Qijun Huang

14 July 2022

In the past few years, deep learning-based electrocardiogram (ECG) compression methods have achieved high-ratio compression by reducing hidden nodes. However, this reduction can result in severe information loss, which will lead to poor quality of th...

  • Article
  • Open Access
7 Citations
4,949 Views
14 Pages

13 July 2022

The severe acute respiratory syndrome related coronavirus 2 (SARS-CoV-2) has spread globally and there is still a lack of rapid detection techniques for SARS-CoV-2 surveillance in indoor air. In this work, two test rigs were developed that enable con...

  • Article
  • Open Access
11 Citations
3,322 Views
22 Pages

13 July 2022

Cell perforation is a critical step for intracellular drug delivery and real-time biosensing of intracellular signals. In recent years, the nanostraws system has been developed to achieve intracellular drug delivery with minimal invasiveness to the c...

  • Article
  • Open Access
44 Citations
6,970 Views
18 Pages

3D Bioprinting of Multi-Material Decellularized Liver Matrix Hydrogel at Physiological Temperatures

  • Vamakshi Khati,
  • Harisha Ramachandraiah,
  • Falguni Pati,
  • Helene A. Svahn,
  • Giulia Gaudenzi and
  • Aman Russom

13 July 2022

Bioprinting is an acclaimed technique that allows the scaling of 3D architectures in an organized pattern but suffers from a scarcity of appropriate bioinks. Decellularized extracellular matrix (dECM) from xenogeneic species has garnered support as a...

  • Communication
  • Open Access
13 Citations
3,453 Views
8 Pages

Short-Term Effect of Cigarette Smoke on Exhaled Volatile Organic Compounds Profile Analyzed by an Electronic Nose

  • Silvano Dragonieri,
  • Vitaliano Nicola Quaranta,
  • Enrico Buonamico,
  • Claudia Battisti,
  • Teresa Ranieri,
  • Pierluigi Carratu and
  • Giovanna Elisiana Carpagnano

13 July 2022

Breath analysis using an electronic nose (e-nose) is an innovative tool for exhaled volatile organic compound (VOC) analysis, which has shown potential in several respiratory and systemic diseases. It is still unclear whether cigarette smoking can be...

  • Article
  • Open Access
25 Citations
4,091 Views
17 Pages

Novel Amperometric Biosensor Based on Tyrosinase/Chitosan Nanoparticles for Sensitive and Interference-Free Detection of Total Catecholamine

  • Valeria Gigli,
  • Cristina Tortolini,
  • Eliana Capecchi,
  • Antonio Angeloni,
  • Andrea Lenzi and
  • Riccarda Antiochia

12 July 2022

The regulation of nervous and cardiovascular systems and some brain-related behaviors, such as stress, panic, anxiety, and depression, are strictly dependent on the levels of the main catecholamines of clinical interest, dopamine (DA), epinephrine (E...

  • Review
  • Open Access
9 Citations
3,508 Views
27 Pages

Paper-Based Fluidic Sensing Platforms for β-Adrenergic Agonist Residue Point-of-Care Testing

  • Hongzhi Luo,
  • Shan Liu,
  • Lina Shi,
  • Zhu Li,
  • Qianwen Bai,
  • Xiaoxin Du,
  • Lijun Wang,
  • He Zha and
  • Chenzhong Li

12 July 2022

The illegal use of β-adrenergic agonists during livestock growth poses a threat to public health; the long-term intake of this medication can cause serious physiological side effects and even death. Therefore, rapid detection methods for β-...

  • Review
  • Open Access
42 Citations
6,523 Views
24 Pages

Magnetoimpedance Biosensors and Real-Time Healthcare Monitors: Progress, Opportunities, and Challenges

  • Valery Ortiz Jimenez,
  • Kee Young Hwang,
  • Dang Nguyen,
  • Yasif Rahman,
  • Claire Albrecht,
  • Baylee Senator,
  • Ongard Thiabgoh,
  • Jagannath Devkota,
  • Vinh Duc An Bui and
  • Manh-Huong Phan
  • + 2 authors

12 July 2022

A small DC magnetic field can induce an enormous response in the impedance of a soft magnetic conductor in various forms of wire, ribbon, and thin film. Also known as the giant magnetoimpedance (GMI) effect, this phenomenon forms the basis for the de...

  • Review
  • Open Access
76 Citations
10,066 Views
37 Pages

12 July 2022

Wearables developed for human body signal detection receive increasing attention in the current decade. Compared to implantable sensors, wearables are more focused on body motion detection, which can support human–machine interaction (HMI) and...

  • Article
  • Open Access
7 Citations
2,534 Views
10 Pages

Supramolecular Enzymatic Labeling for Aptamer Switch-Based Electrochemical Biosensor

  • Anabel Villalonga,
  • Concepción Parrado,
  • Raúl Díaz,
  • Alfredo Sánchez,
  • Beatriz Mayol,
  • Paloma Martínez-Ruíz,
  • Diana Vilela and
  • Reynaldo Villalonga

12 July 2022

Here we report a novel labeling strategy for electrochemical aptasensors based on enzymatic marking via supramolecular host–guest interactions. This approach relies on the use of an adamantane-modified target-responsive hairpin DNA aptamer as a...

  • Article
  • Open Access
12 Citations
3,276 Views
18 Pages

Differential Refractometric Biosensor for Reliable Human IgG Detection: Proof of Concept

  • João P. Mendes,
  • Luís C. C. Coelho,
  • Pedro A. S. Jorge and
  • Carlos M. Pereira

12 July 2022

A new sensing platform based on long-period fiber gratings (LPFGs) for direct, fast, and selective detection of human immunoglobulin G (IgG; Mw = 150 KDa) was developed and characterized. The transducer’s high selectivity is based on the specif...

  • Article
  • Open Access
13 Citations
2,854 Views
11 Pages

An AuNPs-Based Fluorescent Sensor with Truncated Aptamer for Detection of Sulfaquinoxaline in Water

  • Xingyue Chen,
  • Lulan Yang,
  • Jiaming Tang,
  • Xu Wen,
  • Xiaoling Zheng,
  • Lingling Chen,
  • Jiaqi Li,
  • Yong Xie and
  • Tao Le

11 July 2022

Herein, we developed a novel truncation technique for aptamer sequences to fabricate highly sensitive aptasensors based on molecular docking and molecular dynamics simulations. The binding mechanism and energy composition of the aptamer/sulfaquinoxal...

  • Article
  • Open Access
7 Citations
4,310 Views
19 Pages

Microsensor in Microbioreactors: Full Bioprocess Characterization in a Novel Capillary-Wave Microbioreactor

  • Kevin Viebrock,
  • Dominik Rabl,
  • Sven Meinen,
  • Paul Wunder,
  • Jan-Angelus Meyer,
  • Lasse Jannis Frey,
  • Detlev Rasch,
  • Andreas Dietzel,
  • Torsten Mayr and
  • Rainer Krull

11 July 2022

Microbioreactors (MBRs) with a volume below 1 mL are promising alternatives to established cultivation platforms such as shake flasks, lab-scale bioreactors and microtiter plates. Their main advantages are simple automatization and parallelization an...

  • Review
  • Open Access
10 Citations
3,842 Views
25 Pages

11 July 2022

The findings from the synthetic mechanism of metal nanoclusters yield the etching chemistry based on coinage metal nanoclusters. The utilization of such chemistry as a tool that can alter the optical properties of metal nanoclusters has inspired the...

  • Review
  • Open Access
37 Citations
10,279 Views
33 Pages

Signal-Based Methods in Dielectrophoresis for Cell and Particle Separation

  • Malihe Farasat,
  • Ehsan Aalaei,
  • Saeed Kheirati Ronizi,
  • Atin Bakhshi,
  • Shaghayegh Mirhosseini,
  • Jun Zhang,
  • Nam-Trung Nguyen and
  • Navid Kashaninejad

11 July 2022

Separation and detection of cells and particles in a suspension are essential for various applications, including biomedical investigations and clinical diagnostics. Microfluidics realizes the miniaturization of analytical devices by controlling the...

  • Review
  • Open Access
50 Citations
9,372 Views
30 Pages

Wearables for Engagement Detection in Learning Environments: A Review

  • Maritza Bustos-López,
  • Nicandro Cruz-Ramírez,
  • Alejandro Guerra-Hernández,
  • Laura Nely Sánchez-Morales,
  • Nancy Aracely Cruz-Ramos and
  • Giner Alor-Hernández

11 July 2022

Appropriate teaching–learning strategies lead to student engagement during learning activities. Scientific progress and modern technology have made it possible to measure engagement in educational settings by reading and analyzing student physi...

  • Review
  • Open Access
29 Citations
4,416 Views
21 Pages

Progress and Prospects of Electrochemiluminescence Biosensors Based on Porous Nanomaterials

  • Chenchen Li,
  • Jinghui Yang,
  • Rui Xu,
  • Huan Wang,
  • Yong Zhang and
  • Qin Wei

11 July 2022

Porous nanomaterials have attracted much attention in the field of electrochemiluminescence (ECL) analysis research because of their large specific surface area, high porosity, possession of multiple functional groups, and ease of modification. Porou...

  • Article
  • Open Access
22 Citations
4,580 Views
15 Pages

11 July 2022

The consumption of water and milk contaminated with bacteria can lead to foodborne disease outbreaks. For this reason, the development of rapid and sensitive analytical methods for bacteria detection is of primary importance for public health protect...

  • Article
  • Open Access
14 Citations
3,856 Views
13 Pages

10 July 2022

Flourishing in recent years, intelligent electronics is desirably pursued in many fields including bio-symbiotic, human physiology regulatory, robot operation, and human–computer interaction. To support this appealing vision, human-like tactile...

  • Article
  • Open Access
9 Citations
2,976 Views
9 Pages

Mxenes–Au NP Hybrid Plasmonic 2D Microplates in Microfluidics for SERS Detection

  • Zhaoxian Chen,
  • Anping Liu,
  • Xiumei Zhang,
  • Jiawei Jiao,
  • Yuan Yuan,
  • Yingzhou Huang and
  • Sheng Yan

10 July 2022

Combined with microfluidics, surface-enhanced Raman spectroscopy (SERS) exhibits huge application prospective in sensitive online detection. In current studies, the design and optimization of plasmonic enhanced structures in microfluidics for SERS de...

  • Article
  • Open Access
4 Citations
2,926 Views
11 Pages

The Unexpected Selectivity Switching from Mitochondria to Lysosome in a D-π-A Cyanine Dye

  • Chathura S. Abeywickrama,
  • Hannah J. Baumann,
  • Keti A. Bertman,
  • Brian Corbin and
  • Yi Pang

10 July 2022

Two interesting benzothizolium-based D-π-A type hemicyanine dyes (3a3b) with a diphenylamine (-NPh2) donor group were evaluated for fluorescence confocal microscopy imaging ability in live cells (MO3.13, NHLF). In sharp contrast to previous...

  • Review
  • Open Access
32 Citations
7,554 Views
55 Pages

9 July 2022

Food allergy has been indicated as the most frequent adverse reaction to food ingredients over the past few years. Since the only way to avoid the occurrence of allergic phenomena is to eliminate allergenic foods, it is essential to have complete and...

  • Article
  • Open Access
10 Citations
3,426 Views
17 Pages

Classification of Dysphonic Voices in Parkinson’s Disease with Semi-Supervised Competitive Learning Algorithm

  • Guidong Bao,
  • Mengchen Lin,
  • Xiaoqian Sang,
  • Yangcan Hou,
  • Yixuan Liu and
  • Yunfeng Wu

9 July 2022

This article proposes a novel semi-supervised competitive learning (SSCL) algorithm for vocal pattern classifications in Parkinson’s disease (PD). The acoustic parameters of voice records were grouped into the families of jitter, shimmer, harmo...

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