Next Article in Journal
New ECG Compression Method for Portable ECG Monitoring System Merged with Binary Convolutional Auto-Encoder and Residual Error Compensation
Previous Article in Journal
Interrogation on the Cellular Nano-Interface and Biosafety of Repeated Nano-Electroporation by Nanostraw System
 
 
Article

SARS-CoV-2 Surveillance in Indoor Air Using Electrochemical Sensor for Continuous Monitoring and Real-Time Alerts

Chemical and Electrochemical Technology and Innovation (CETI) Laboratory, Department of Chemical Engineering, Texas Tech University, Lubbock, TX 79409, USA
*
Author to whom correspondence should be addressed.
Biosensors 2022, 12(7), 523; https://doi.org/10.3390/bios12070523
Received: 10 June 2022 / Revised: 5 July 2022 / Accepted: 10 July 2022 / Published: 13 July 2022
(This article belongs to the Section Biosensors and Healthcare)
The severe acute respiratory syndrome related coronavirus 2 (SARS-CoV-2) has spread globally and there is still a lack of rapid detection techniques for SARS-CoV-2 surveillance in indoor air. In this work, two test rigs were developed that enable continuous air monitoring for the detection of SARS-CoV-2 by sample collection and testing. The collected samples from simulated SARS-CoV-2 contaminated air were analyzed using an ultra-fast COVID-19 diagnostic sensor (UFC-19). The test rigs utilized two air sampling methods: cyclone-based collection and internal impaction. The former achieved a limit of detection (LoD) of 0.004 cp/L in the air (which translates to 0.5 cp/mL when tested in aqueous solution), lower than the latter with a limit of 0.029 cp/L in the air. The LoD of 0.5 cp/mL using the UFC-19 sensor in aqueous solution is significantly lower than the best-in-class assays (100 cp/mL) and FDA EUA RT-PCR test (6250 cp/mL). In addition, the developed test rig provides an ultra-fast method to detect airborne SARS-CoV-2. The required time to test 250 L air is less than 5 min. While most of the time is consumed by the air collection process, the sensing is completed in less than 2 s using the UFC-19 sensor. This method is much faster than both the rapid antigen (<20 min) and RT-PCR test (<90 min). View Full-Text
Keywords: rapid detection technique; SARS-CoV-2 surveillance; continuous air monitoring; SARS-CoV-2 air collection; electrochemical SARS-CoV-2 sensor; air sampling rapid detection technique; SARS-CoV-2 surveillance; continuous air monitoring; SARS-CoV-2 air collection; electrochemical SARS-CoV-2 sensor; air sampling
Show Figures

Figure 1

MDPI and ACS Style

Lu, F.; Gecgel, O.; Ramanujam, A.; Botte, G.G. SARS-CoV-2 Surveillance in Indoor Air Using Electrochemical Sensor for Continuous Monitoring and Real-Time Alerts. Biosensors 2022, 12, 523. https://doi.org/10.3390/bios12070523

AMA Style

Lu F, Gecgel O, Ramanujam A, Botte GG. SARS-CoV-2 Surveillance in Indoor Air Using Electrochemical Sensor for Continuous Monitoring and Real-Time Alerts. Biosensors. 2022; 12(7):523. https://doi.org/10.3390/bios12070523

Chicago/Turabian Style

Lu, Fei, Ozhan Gecgel, Ashwin Ramanujam, and Gerardine G. Botte. 2022. "SARS-CoV-2 Surveillance in Indoor Air Using Electrochemical Sensor for Continuous Monitoring and Real-Time Alerts" Biosensors 12, no. 7: 523. https://doi.org/10.3390/bios12070523

Find Other Styles
Note that from the first issue of 2016, MDPI journals use article numbers instead of page numbers. See further details here.

Article Access Map by Country/Region

1
Back to TopTop