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Biosensors, Volume 12, Issue 7

July 2022 - 118 articles

Cover Story: In this study, the development of the first electrochemical aptasensor for the detection of 3-O-C12-HSL is reported. A carbon-based screen-printed electrode modified with gold nanoparticles proved to be the best platform for the aptasensor. Each step in the fabrication of the aptasensor (i.e., the deposition of gold nanoparticles, aptamer immobilization, and incubation with the analyte) was optimized and characterized using cyclic voltammetry, differential pulse voltammetry, and electrochemical impedance spectroscopy. Different redox probes were evaluated in the solution, with the best results being obtained in the presence of [Fe(CN)6]4−/[Fe(CN)6]3−. The binding affinity of 106.7 nM for the immobilized thiol-terminated aptamer was determined using surface plasmon resonance. View this paper
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Articles (118)

  • Article
  • Open Access
14 Citations
3,062 Views
12 Pages

Millimeter Wave-Based Non-Destructive Biosensor System for Live Fish Monitoring

  • Meng Wang,
  • Yunyue Yang,
  • Boyu Mu,
  • Marina A. Nikitina and
  • Xinqing Xiao

20 July 2022

Waterless transportation for live grouper is a novel mode of transport that not only saves money, but also lowers wastewater pollution. Technical obstacles remain, however, in achieving intelligent monitoring and a greater survival rate. During live...

  • Article
  • Open Access
22 Citations
5,886 Views
18 Pages

Flexible Glassy Carbon Multielectrode Array for In Vivo Multisite Detection of Tonic and Phasic Dopamine Concentrations

  • Elisa Castagnola,
  • Elaine M. Robbins,
  • Bingchen Wu,
  • May Yoon Pwint,
  • Raghav Garg,
  • Tzahi Cohen-Karni and
  • Xinyan Tracy Cui

20 July 2022

Dopamine (DA) plays a central role in the modulation of various physiological brain functions, including learning, motivation, reward, and movement control. The DA dynamic occurs over multiple timescales, including fast phasic release, as a result of...

  • Article
  • Open Access
4 Citations
2,911 Views
12 Pages

Ultralow Laser Power Three-Dimensional Superresolution Microscopy Based on Digitally Enhanced STED

  • Xiaochun Shen,
  • Luwei Wang,
  • Wei Li,
  • He Wang,
  • Hanqiu Zhou,
  • Yinru Zhu,
  • Wei Yan and
  • Junle Qu

20 July 2022

The resolution of optical microscopes is limited by the optical diffraction limit; in particular, the axial resolution is much lower than the lateral resolution, which hinders the clear distinction of the three-dimensional (3D) structure of cells. Al...

  • Article
  • Open Access
12 Citations
3,583 Views
24 Pages

20 July 2022

Developing rapid, sensitive detection methods for 3,4-Methylenedioxymethylamphetamine (MDMA) is crucial to reduce its current misuse in the world population. With that aim, we developed an aptamer-modified tin nanoparticle (SnNP)-based nanoarchitectu...

  • Article
  • Open Access
1 Citations
3,780 Views
15 Pages

A Point-of-Care Device for Fully Automated, Fast and Sensitive Protein Quantification via qPCR

  • Francesca Romana Cavallo,
  • Khalid Baig Mirza,
  • Sara de Mateo,
  • Luca Miglietta,
  • Jesus Rodriguez-Manzano ,
  • Konstantin Nikolic and
  • Christofer Toumazou

19 July 2022

This paper presents a fully automated point-of-care device for protein quantification using short-DNA aptamers, where no manual sample preparation is needed. The device is based on our novel aptamer-based methodology combined with real-time polymeras...

  • Article
  • Open Access
15 Citations
3,445 Views
11 Pages

18 July 2022

A highly sensitive and precise Love wave mode surface acoustic wave (SAW) immunosensor based on an ST-cut 90°X quartz substrate and an SiO2 wave-guiding layer was developed to detect cancer-related biomarkers of carcinoembryonic antigens (CEAs)....

  • Article
  • Open Access
71 Citations
3,328 Views
13 Pages

Optical Detection of Fat Concentration in Milk Using MXene-Based Surface Plasmon Resonance Structure

  • Abdulkarem H. M. Almawgani,
  • Malek G. Daher,
  • Sofyan A. Taya,
  • Mohammad Mashagbeh and
  • Ilhami Colak

18 July 2022

MXene (Ti3C2Tx) has emerged very recently as an interacting material for surface plasmon resonance (SPR) configuration. It was discovered that Ti3C2Tx can facilitate the adsorption of biomolecules due to its higher binding energies, stronger interact...

  • Article
  • Open Access
9 Citations
3,874 Views
15 Pages

Design and Realization of MEMS Heart Sound Sensor with Concave, Racket-Shaped Cilium

  • Yuhua Yang,
  • Bo Wang,
  • Jiangong Cui,
  • Guojun Zhang,
  • Renxin Wang,
  • Wendong Zhang,
  • Changde He,
  • Yirui Li,
  • Pengcheng Shi and
  • Shuotong Wang

18 July 2022

The biomedical acoustic signal plays an important role in clinical non-invasive diagnosis. In view of the deficiencies in early diagnosis of cardiovascular diseases, acoustic properties of S1 and S2 heart sounds are utilized. In this paper, we propos...

  • Article
  • Open Access
12 Citations
3,851 Views
14 Pages

17 July 2022

The detection of miRNA shows great promise in disease diagnosis. In this work, a ratiometric fluorescent biosensor based on multi-walled carbon nanotubes@gold nanoclusters (MWCNTs@Au NCs) and duplex-specific nuclease (DSN)-assisted signal amplificati...

  • Review
  • Open Access
31 Citations
8,113 Views
29 Pages

16 July 2022

Bacterial contamination is a public health concern worldwide causing enormous social and economic losses. For early diagnosis and adequate management to prevent or treat pathogen-related illnesses, extensive effort has been put into the development o...

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Biosensors - ISSN 2079-6374