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Vaccines, Volume 9, Issue 6

June 2021 - 147 articles

Cover Story: Polymer-based systems are considered as the next generation of nanovaccines. The properties, the characteristics, the added value, and the limitations of the polymer-based nanovaccines, as well as their development process by the pharmaceutical industry, are presented in this review. Polymer-based nanovaccines exhibit several advantages, such as strong cellular immune responses, adjuvant properties, increased secretion of cytokines, co-loading and prolonged circulation of antigens and increased levels of antibodies and antigen-specific antibodies. Additionally, different and needle-free routes of administration are available for the polymer-based nanovaccines. Considering the formulation diversity of polymer-based nanovaccines is a new horizon for vaccinology in the coming years. View this paper.
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Articles (147)

  • Article
  • Open Access
14 Citations
5,345 Views
10 Pages

COVID-19 Vaccine Acceptance in Azuay Province, Ecuador: A Cross-Sectional Online Survey

  • Julio Jaramillo-Monge,
  • Michael Obimpeh,
  • Bernardo Vega,
  • David Acurio,
  • Annelies Boven,
  • Veronique Verhoeven and
  • Robert Colebunders

We investigated the COVID-19 vaccination acceptance level in Azuay province, Ecuador through an online survey from 12th to 26th February (before the start of the COVID-19 vaccination campaign in Ecuador). Overall, 1219 respondents participated in the...

  • Review
  • Open Access
79 Citations
12,550 Views
19 Pages

This review describes investigations of specific topics that lie within the general subject of HSV1’s role in AD/dementia, published in the last couple of years. They include studies on the following: relationship of HSV1 to AD using neural stem cell...

  • Review
  • Open Access
2 Citations
3,726 Views
33 Pages

HLA class-I (HLA-I) polyreactive monoclonal antibodies (mAbs) reacting to all HLA-I alleles were developed by immunizing mice with HLA-E monomeric, α-heavy chain (αHC) open conformers (OCs). Two mAbs (TFL-006 and TFL-007) were bound to the αHC’s coat...

  • Article
  • Open Access
4 Citations
2,802 Views
12 Pages

Immunization Catch-Up for Newly Arrived Migrants in France: A Cross-Sectional Study among French General Practitioners

  • Sohela Moussaoui,
  • Anne Marie Aurousseau,
  • Sylvain Nappez,
  • Julian Cornaglia,
  • Gaylord Delobre,
  • Sophie Blanchi,
  • Louise Luan,
  • Stéphanie Vandentorren,
  • Olivier Bouchaud and
  • Odile Launay
  • + 5 authors

Background: Migrants often undergo an incomplete vaccination program in regards to the French recommendations. The aim of this study was to evaluate the practices of French General Practitioners’ (GPs) in terms of catch-up vaccination. Methods: A cro...

  • Article
  • Open Access
30 Citations
5,757 Views
20 Pages

Attitudes towards the COVID-19 Vaccine and Willingness to Get Vaccinated among Healthcare Workers in French Guiana: The Influence of Geographical Origin

  • Nicolas Vignier,
  • Kepha Brureau,
  • Sybille Granier,
  • Jacques Breton,
  • Céline Michaud,
  • Mélanie Gaillet,
  • Camille Agostini,
  • Mathilde Ballet,
  • Mathieu Nacher and
  • Audrey Valdes
  • + 5 authors

Background: In the context of the global COVID-19 pandemic and the expansion of the more transmissible 20J/501Y.V3 (Gamma) variant of concern (VOC), mRNA vaccines have been made available in French Guiana, an overseas French territory in South Americ...

  • Article
  • Open Access
3 Citations
2,845 Views
12 Pages

Influenza Illness and Partial Vaccination in the First Two Years of Life

  • Abram L. Wagner,
  • Lionel Gresh,
  • Nery Sanchez,
  • Guillermina Kuan,
  • John Kubale,
  • Roger Lopez,
  • Sergio Ojeda,
  • Eduardo Azziz-Baumgartner,
  • Angel Balmaseda and
  • Aubree Gordon

More information about influenza in low- and middle-income countries could guide the establishment of pediatric influenza vaccine programs. This study (1) characterizes the burden of influenza in infants, and (2) compares signs and symptoms by prior...

  • Perspective
  • Open Access
7 Citations
7,482 Views
8 Pages

Evaluating Functional Immunity Following Encapsulated Bacterial Infection and Vaccination

  • Zheng Quan Toh,
  • Rachel A. Higgins,
  • Nadia Mazarakis,
  • Elysia Abbott,
  • Jordan Nathanielsz,
  • Anne Balloch,
  • Kim Mulholland and
  • Paul V. Licciardi

Encapsulated bacteria such as Streptococcus pneumoniae, Haemophilus influenzae type b and Neisseria meningitidis cause significant morbidity and mortality in young children despite the availability of vaccines. Highly specific antibodies are the prim...

  • Communication
  • Open Access
49 Citations
10,382 Views
9 Pages

Background: The coronavirus disease 2019 (COVID-19) pandemic has given rise to the need to develop a vaccine as quickly as possible. As pregnant women are at increased risk of contracting severe COVID-19, with higher mortality, it is essential to ass...

  • Article
  • Open Access
33 Citations
4,496 Views
9 Pages

BNT162b2 mRNA SARS-CoV-2 Vaccine Elicits High Avidity and Neutralizing Antibodies in Healthcare Workers

  • Federico Pratesi,
  • Teresita Caruso,
  • Davide Testa,
  • Tiziano Tarpanelli,
  • Alessandra Gentili,
  • Davide Gioè and
  • Paola Migliorini

The BNT162b2 vaccine, containing lipid nanoparticles-formulated mRNA encoding the full-length spike protein of SARS-CoV-2, has been employed to immunize health care workers in Italy, administered in two doses 21 days apart. In this study, we characte...

  • Review
  • Open Access
10 Citations
4,348 Views
12 Pages

What Constitutes Protective Immunity Following Yellow Fever Vaccination?

  • Jolynne Mokaya,
  • Derick Kimathi,
  • Teresa Lambe and
  • George M. Warimwe

Yellow fever (YF) remains a threat to global health, with an increasing number of major outbreaks in the tropical areas of the world over the recent past. In light of this, the Eliminate Yellow Fever Epidemics Strategy was established with the aim of...

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Vaccines - ISSN 2076-393XCreative Common CC BY license