An Antigenic Thrift-Based Approach to Influenza Vaccine Design
Abstract
:1. Introduction
1.1. Antigenic Drift
1.2. Antigenic Thrift
1.3. Vaccine Approaches
2. Vaccines Targeting More Conserved Regions of the Influenza Virus
3. An Antigenic Thrift Approach to Universal Influenza Vaccine Design
4. Pitfalls of Effective Universal Vaccine Development
5. Concluding Remarks and Future Perspectives
Author Contributions
Funding
Institutional Review Board Statement
Informed Consent Statement
Data Availability Statement
Acknowledgments
Conflicts of Interest
Appendix A
Appendix A.1. Methods
Appendix A.2. Phylogenetic Analysis
References
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Bolton, J.S.; Klim, H.; Wellens, J.; Edmans, M.; Obolski, U.; Thompson, C.P. An Antigenic Thrift-Based Approach to Influenza Vaccine Design. Vaccines 2021, 9, 657. https://doi.org/10.3390/vaccines9060657
Bolton JS, Klim H, Wellens J, Edmans M, Obolski U, Thompson CP. An Antigenic Thrift-Based Approach to Influenza Vaccine Design. Vaccines. 2021; 9(6):657. https://doi.org/10.3390/vaccines9060657
Chicago/Turabian StyleBolton, Jai S., Hannah Klim, Judith Wellens, Matthew Edmans, Uri Obolski, and Craig P. Thompson. 2021. "An Antigenic Thrift-Based Approach to Influenza Vaccine Design" Vaccines 9, no. 6: 657. https://doi.org/10.3390/vaccines9060657