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Antioxidants, Volume 10, Issue 8

August 2021 - 173 articles

Cover Story: Sepsis causes high mortality in the context of septic shock. Here, we investigate the effects of Lira in a polymicrobial sepsis model of cecal ligation and puncture (CLP).
Aortic vascular function (isometric tension recording), protein expression (immunohistochemistry and dot blot), and gene expression (qRT-PCR) were determined. We demonstrate that the GLP-1 analog Lira ameliorates sepsis-induced endothelial dysfunction by the reduction of vascular inflammation and oxidative stress. Accordingly, the findings suggest that the antioxidant and anti-inflammatory effects of GLP-1 analogs may be a valuable tool to protect the cardiovascular system from dysbalanced inflammation in polymicrobial sepsis. View this paper.
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Articles (173)

  • Article
  • Open Access
23 Citations
4,562 Views
20 Pages

Silicon Improves the Redox Homeostasis to Alleviate Glyphosate Toxicity in Tomato Plants—Are Nanomaterials Relevant?

  • Cristiano Soares,
  • Pedro Nadais,
  • Bruno Sousa,
  • Edgar Pinto,
  • Isabel M. P. L. V. O. Ferreira,
  • Ruth Pereira and
  • Fernanda Fidalgo

23 August 2021

Given the widespread use of glyphosate (GLY), this agrochemical is becoming a source of contamination in agricultural soils, affecting non-target plants. Therefore, sustainable strategies to increase crop tolerance to GLY are needed. From this perspe...

  • Article
  • Open Access
16 Citations
4,964 Views
16 Pages

23 August 2021

Alzheimer’s disease (AD) is a progressive neurodegenerative disorder resulting in cognitive decline or dementia, the number of patients with AD is continuously increasing. Although a lot of great progress has been made in research and development of...

  • Article
  • Open Access
10 Citations
3,646 Views
14 Pages

Association of Particulate Matter from Cooking Oil Fumes with Heart Rate Variability and Oxidative Stress

  • Chang-Chuan Chan,
  • Lian-Yu Lin,
  • Ching-Huang Lai,
  • Kai-Jen Chuang,
  • Ming-Tsang Wu and
  • Chih-Hong Pan

23 August 2021

Many studies have reported various cardiovascular autonomic responses to ambient particulate matter (PM) pollution, but few have reported such responses to occupational PM exposures. Even fewer have demonstrated a relationship between PM pollution an...

  • Article
  • Open Access
26 Citations
4,584 Views
16 Pages

23 August 2021

Inflammation is the first response of the immune system against bacterial pathogens. This study isolated and examined an antioxidant derived from Lactobacillus fermentation products using cultured media with 1% beet powder. The antioxidant activity o...

  • Article
  • Open Access
30 Citations
7,559 Views
18 Pages

Effects of pH and Temperature on Water under Pressurized Conditions in the Extraction of Nutraceuticals from Chaga (Inonotus obliquus) Mushroom

  • Ibrahim M. Abu-Reidah,
  • Amber L. Critch,
  • Charles F. Manful,
  • Amanda Rajakaruna,
  • Natalia P. Vidal,
  • Thu H. Pham,
  • Mumtaz Cheema and
  • Raymond Thomas

23 August 2021

Currently, there is increased interest in finding appropriate food-grade green extraction systems capable of extracting these bioactive compounds from dietary mushrooms for applications in various food, pharmacological, or nutraceutical formulations....

  • Review
  • Open Access
90 Citations
25,205 Views
25 Pages

Role of Coenzyme Q10 in Health and Disease: An Update on the Last 10 Years (2010–2020)

  • Ilenia Cirilli,
  • Elisabetta Damiani,
  • Phiwayinkosi Vusi Dludla,
  • Iain Hargreaves,
  • Fabio Marcheggiani,
  • Lauren Elizabeth Millichap,
  • Patrick Orlando,
  • Sonia Silvestri and
  • Luca Tiano

23 August 2021

The present review focuses on preclinical and clinical studies conducted in the last decade that contribute to increasing knowledge on Coenzyme Q10’s role in health and disease. Classical antioxidant and bioenergetic functions of the coenzyme have be...

  • Article
  • Open Access
27 Citations
4,334 Views
17 Pages

Effects of a Nanoencapsulated Moringa Leaf Ethanolic Extract on the Physiology, Metabolism and Reproductive Performance of Rabbit Does during Summer

  • Nagwa I. El-Desoky,
  • Nesrein M. Hashem,
  • Antonio Gonzalez-Bulnes,
  • Ahmed G. Elkomy and
  • Zahraa R. Abo-Elezz

23 August 2021

This study investigated the effect of Moringa leaf ethanolic extract (MLEE) on heat-tolerance variables and the reproductive performance of rabbit does bred under hot climate conditions. Additionally, the effect of nanoencapsulation technology on the...

  • Article
  • Open Access
21 Citations
4,602 Views
15 Pages

Enzymatic Production of 3-OH Phlorizin, a Possible Bioactive Polyphenol from Apples, by Bacillus megaterium CYP102A1 via Regioselective Hydroxylation

  • Ngoc Anh Nguyen,
  • Ngoc Tan Cao,
  • Thi Huong Ha Nguyen,
  • Jung-Hwan Ji,
  • Gun Su Cha,
  • Hyung-Sik Kang and
  • Chul-Ho Yun

23 August 2021

Phlorizin is the most abundant glucoside of phloretin from the apple tree and its products. Phlorizin and its aglycone phloretin are currently considered health-beneficial polyphenols from apples useful in treating hyperglycemia and obesity. Recently...

  • Review
  • Open Access
34 Citations
6,601 Views
15 Pages

23 August 2021

Amyotrophic lateral sclerosis (ALS) and frontotemporal dementia (FTD) are severe neurodegenerative disorders that belong to a common disease spectrum. The molecular and cellular aetiology of the spectrum is a highly complex encompassing dysfunction i...

  • Article
  • Open Access
22 Citations
4,807 Views
11 Pages

Dietary Blueberry and Soluble Fiber Improve Serum Antioxidant and Adipokine Biomarkers and Lipid Peroxidation in Pregnant Women with Obesity and at Risk for Gestational Diabetes

  • Arpita Basu,
  • Jeannette Crew,
  • Jeffrey L. Ebersole,
  • Jefferson W. Kinney,
  • Arnold M. Salazar,
  • Petar Planinic and
  • James M. Alexander

22 August 2021

Pregnancies affected by obesity are at high risk for developing metabolic complications with oxidative stress and adipocyte dysfunction contributing to the underlying pathologies. Few studies have examined the role of dietary interventions, especiall...

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Antioxidants - ISSN 2076-3921