You are currently on the new version of our website. Access the old version .

Brain Sciences, Volume 10, Issue 10

2020 October - 101 articles

Cover Story: Children with fragile X syndrome (FXS) exhibit deficits in a variety of cognitive processes within the executive function domain. As working memory (WM) is known to support a wide range of cognitive, learning and adaptive functions, WM computer-based training programs have the potential to benefit people with FXS and other forms of intellectual and developmental disability (IDD). However, research on the effectiveness of WM training has been mixed. The current study is a follow-up “deep dive” into the data collected during a randomized controlled trial of Cogmed (Stockholm, Sweden) WM training in children with FXS. View this paper
  • Issues are regarded as officially published after their release is announced to the table of contents alert mailing list .
  • You may sign up for email alerts to receive table of contents of newly released issues.
  • PDF is the official format for papers published in both, html and pdf forms. To view the papers in pdf format, click on the "PDF Full-text" link, and use the free Adobe Reader to open them.

Articles (101)

  • Article
  • Open Access
9 Citations
4,321 Views
15 Pages

Chronic Valproic Acid Administration Increases Plasma, Liver, and Brain Ammonia Concentration and Suppresses Glutamine Synthetase Activity

  • Abdelnaser A. Badawy,
  • Rasha Elghaba,
  • Mohamed Soliman,
  • Abdelaziz M. Hussein,
  • Sana A. AlSadrah,
  • Amira Awadalla and
  • Osama A. Abulseoud

21 October 2020

Asymptomatic valproic acid (VPA)-induced hyperammonemia in the absence of liver impairment is fairly common. However, the underlying mechanisms through which VPA causes elevation in plasma ammonia (NH4) remains under investigation. Male Sprague Dawle...

  • Article
  • Open Access
13 Citations
4,121 Views
19 Pages

Glycyrrhizin Blocks the Detrimental Effects of HMGB1 on Cortical Neurogenesis after Traumatic Neuronal Injury

  • Susruta Manivannan,
  • Balkis Harari,
  • Maryam Muzaffar,
  • Omar Elalfy,
  • Sameera Hettipathirannahelage,
  • Zoe James,
  • Feras Sharouf,
  • Chloe Ormonde,
  • Mouhamed Alsaqati and
  • Malik Zaben
  • + 1 author

21 October 2020

Despite medical advances, neurological recovery after severe traumatic brain injury (TBI) remains poor. Elevated levels of high mobility group box protein-1 (HMGB1) are associated with poor outcomes; likely via interaction with receptors for advanced...

  • Article
  • Open Access
7 Citations
3,672 Views
15 Pages

A Disruption in the Balance of Attentional Systems Plays a Role in Trait Anxiety

  • Mark R. Minnick,
  • Koraly E. Pérez-Edgar and
  • José A. Soto

21 October 2020

Elevated levels of anxiety are associated with attentional threat biases and inefficient attentional control, with the latter requiring sustained cognitive effort. The current study assessed self-reported and behavioral evidence of attentional functi...

  • Article
  • Open Access
2 Citations
2,917 Views
11 Pages

The Relationship between Carotid Doppler Ultrasound and EEG Metrics in Healthy Preschoolers and Adults

  • Galina V. Portnova,
  • Aleksandra V. Maslennikova and
  • Elena V. Proskurnina

20 October 2020

Despite widespread using electroencephalography (EEG) and Doppler ultrasound in pediatric neurology clinical practice, there are still no well-known correlations between these methods that could contribute to a better understanding of brain processes...

  • Article
  • Open Access
12 Citations
3,998 Views
14 Pages

20 October 2020

The cuneiform nucleus (CN) and the pedunculopontine nucleus (PPN) in the midbrain control coordinated locomotion in vertebrates, but whether similar mechanisms exist in humans remain to be elucidated. Using functional magnetic resonance imaging, we f...

  • Review
  • Open Access
11 Citations
5,376 Views
17 Pages

20 October 2020

Most adults who acquire hearing loss find it to be a disability that is poorly corrected by current prosthetics. This gap drives current research in cochlear mechanosensory hair cell regeneration and in hearing restoration. Birds and fish can spontan...

  • Review
  • Open Access
71 Citations
19,686 Views
13 Pages

Anti-CD20 Agents for Multiple Sclerosis: Spotlight on Ocrelizumab and Ofatumumab

  • Despoina Florou,
  • Maria Katsara,
  • Jack Feehan,
  • Efthimios Dardiotis and
  • Vasso Apostolopoulos

20 October 2020

Until recently, in the pathogenesis of Multiple Sclerosis (MS), the contribution of B cells has been largely underestimated, and the disease was considered a T-cell-mediated disorder. However, newer evidence shows that B cells play a crucial role in...

  • Brief Report
  • Open Access
2 Citations
2,986 Views
8 Pages

Understanding Novel Metaphors: A Milestone in the Developmental Trajectory of Children with Agenesis of the Corpus Callosum?

  • Sergio Melogno,
  • Maria Antonietta Pinto,
  • Chiara Pollice,
  • Fausto Badolato,
  • Guido Trasimeni and
  • Pasquale Parisi

19 October 2020

This study explores novel metaphor comprehension in a 7.2-year-old child (conventionally called RJ) with complete and isolated agenesis of the corpus callosum (ACC). RJ’s cognitive level was adequate for his age as well as most of his linguisti...

  • Article
  • Open Access
14 Citations
4,353 Views
22 Pages

19 October 2020

Autism disorder, generally known as Autism Spectrum Disorder (ASD) is a brain disorder characterized by lack of communication skills, social aloofness and repetitions in the actions in the patients, which is affecting millions of the people across th...

  • Feature Paper
  • Review
  • Open Access
15 Citations
6,961 Views
27 Pages

The Influence of Recreational Substance Use in TMS Research

  • Claudia V. Turco,
  • Sarah O. Arsalan and
  • Aimee J. Nelson

18 October 2020

(1) Background: Transcranial magnetic stimulation (TMS) approaches are widely used to study cortical and corticospinal function. However, responses to TMS are subject to significant intra-and inter-individual variability. Acute and chronic exposure t...

of 11

Get Alerted

Add your email address to receive forthcoming issues of this journal.

XFacebookLinkedIn
Brain Sci. - ISSN 2076-3425