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Brain Sciences, Volume 10, Issue 11

November 2020 - 135 articles

Cover Story: Pathological inclusions known as neurofibrilary tangles, composed of the microtubule associated protein tau (tau), are a typical pathological hallmark in Alzheimer’s and other neurodegenerative disorders. Tau pathology seems to spread between neurons as disease progresses, but the precise mechanisms underlying pathology spreading are still unclear. Nevertheless, pharmacological modulation of tau aggregation and spreading between neurons is a promising strategy for therapeutic intervention. View this paper
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Articles (135)

  • Review
  • Open Access
34 Citations
5,254 Views
20 Pages

23 November 2020

Transplantation of neural stem cells (NSCs) has been proposed as an alternative novel therapy to replace damaged neural circuitry after ischemic stroke onset. Nonetheless, albeit the potential of these cells for stroke therapy, many critical challeng...

  • Article
  • Open Access
15 Citations
4,536 Views
9 Pages

Fatal Status Epilepticus in Dravet Syndrome

  • Paola De Liso,
  • Virginia Pironi,
  • Massimo Mastrangelo,
  • Domenica Battaglia,
  • Dana Craiu,
  • Marina Trivisano,
  • Nicola Specchio,
  • Rima Nabbout and
  • Federico Vigevano

23 November 2020

Dravet Syndrome (DS) is burdened by high epilepsy-related premature mortality due to status epilepticus (SE). We surveyed centres within Europe through the Dravet Italia Onlus and EpiCARE network (European Reference Network for Rare and Complex Epile...

  • Article
  • Open Access
14 Citations
3,191 Views
17 Pages

23 November 2020

The medial olivocochlear (MOC) system is thought to be responsible for modulation of peripheral hearing through descending (efferent) pathways. This study investigated the connection between peripheral hearing function and conscious attention during...

  • Review
  • Open Access
36 Citations
22,848 Views
30 Pages

U-47700 and Its Analogs: Non-Fentanyl Synthetic Opioids Impacting the Recreational Drug Market

  • Michael H. Baumann,
  • Graziella Tocco,
  • Donna M. Papsun,
  • Amanda L. Mohr,
  • Melissa F. Fogarty and
  • Alex J. Krotulski

23 November 2020

The recreational use of opioid drugs is a global threat to public health and safety. In particular, an epidemic of opioid overdose fatalities is being driven by illicitly manufactured fentanyl, while novel synthetic opioids (NSOs) are appearing on re...

  • Article
  • Open Access
5 Citations
4,079 Views
34 Pages

23 November 2020

Deaf and Hard of Hearing (DHH) children show difficulties in reading aloud and comprehension of texts. Here, we examined the hypothesis that these reading difficulties are tightly related to the syntactic deficit displayed by DHH children. We first a...

  • Article
  • Open Access
6 Citations
2,590 Views
15 Pages

22 November 2020

Ultrasonic vocalizations (USVs) are well-established markers of motivational and emotional status. Recent work from our lab has provided novel evidence for a role of USVs in models of ethanol (EtOH) use. For instance, USV acoustic characteristics can...

  • Article
  • Open Access
4 Citations
3,636 Views
13 Pages

The Association between Diurnal Sleep Patterns and Emotions in Infants and Toddlers Attending Nursery

  • Valeria Bacaro,
  • Bernd Feige,
  • Fee Benz,
  • Anna F. Johann,
  • Paola De Bartolo,
  • Alessandra Devoto,
  • Caterina Lombardo,
  • Dieter Riemann and
  • Chiara Baglioni

22 November 2020

Background: Childcare programs often include mandatory naptime during the day. Loss of daytime sleep could lead to a moderate-to-large decrease in self-regulation, emotion processing, and learning in early childhood. Nevertheless, daytime sleep has b...

  • Article
  • Open Access
29 Citations
5,816 Views
14 Pages

Using Hybrid Telepractice for Supporting Parents of Children with ASD during the COVID-19 Lockdown: A Feasibility Study in Iran

  • Sayyed Ali Samadi,
  • Shahnaz Bakhshalizadeh-Moradi,
  • Fatemeh Khandani,
  • Mehdi Foladgar,
  • Maryam Poursaid-Mohammad and
  • Roy McConkey

22 November 2020

During the three-month closure of clinics and day centers in Iran due to the coronavirus disease 2019 (COVID-19) lockdown, parents of children with Autism Spectrum Disorder (ASD) became solely responsible for their care and education. Although center...

  • Article
  • Open Access
16 Citations
4,061 Views
10 Pages

Low Intensity, Transcranial, Alternating Current Stimulation Reduces Migraine Attack Burden in a Home Application Set-Up: A Double-Blinded, Randomized Feasibility Study

  • Andrea Antal,
  • Rebecca Bischoff,
  • Caspar Stephani,
  • Dirk Czesnik,
  • Florian Klinker,
  • Charles Timäus,
  • Leila Chaieb and
  • Walter Paulus

21 November 2020

Background: Low intensity, high-frequency transcranial alternating current stimulation (tACS) applied over the motor cortex decreases the amplitude of motor evoked potentials. This double-blind, placebo-controlled parallel group study aimed to test t...

  • Article
  • Open Access
27 Citations
11,048 Views
12 Pages

20 November 2020

Studies on the structure of intelligence refer to two main theoretical models: the first one considers intelligence as a unitary construct, the second one assumes the involvement of a plurality of factors. Studies using Raven’s Coloured Progres...

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Brain Sci. - ISSN 2076-3425