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Brain Sciences publishes Special Issues to create collections of papers on specific topics, with the aim of building a community of authors and readers to discuss the latest research and develop new ideas and research directions. Special Issues are led by Guest Editors, who are experts on the topic and all Special Issue submissions follow MDPI's standard editorial process. The journal’s Editor-in-Chief and/or designated Editorial Board Member will oversee Guest Editor appointments and Special Issue proposals, checking their content for relevance and ensuring the suitability of the material for the journal. The papers published in a Special Issue will be collected and displayed on a dedicated page of the journal’s website. Further information on MDPI's Special Issue policies and Guest Editor responsibilities can be found here. For any inquiries related to a Special Issue, please contact the Editorial Office.

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Advanced Technologies and Approaches for Understanding and Treating Psychological Disorders

edited by

Alessandra Vergallito

submission deadline 20 Feb 2026 | 1 articles | Viewed by 4454

Keywords: psychological disorders; psychological well-being; psychological interventions; non-invasive brain stimulation; digital therapies; artificial intelligence; virtual reality; pharmacological interventions

(This special issue belongs to the Section Neuropsychiatry)

Advances in Cerebral Aneurysm Surgery: The Latest Technologies and Techniques

edited by Andreas Gruber

submission deadline 20 Feb 2026 | 2 articles | Viewed by 2106

Keywords: microsurgical aneurysm clipping; preoperative simulation; hybrid neurovascular surgery; skills-lab training; intraoperative monitoring and imaging

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Non-Invasive Neural Technology in Analysing Spinal Cord Activity

edited by

Giulio Gabrieli

submission deadline 20 Feb 2026 | Viewed by 231

Keywords: spinal cord; non-invasive recording; electrophysiology; neurotechnology; signal processing; artifact reduction; wearable sensors; machine learning

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Cognitive Training in Health and Disease

edited by

María del Carmen Carcelén-Fraile

submission deadline 22 Feb 2026 | Viewed by 235 | Submission Open

Keywords: cognitive training; child development; adolescence; executive functions; cognitive stimulation; mental health; neurodevelopmental disorders; healthy aging; education and cognition

(This special issue belongs to the Section Cognitive Neuroscience)

Eye-Tracking Monitoring of Neurological and Psychiatric Conditions Across Life Span

edited by

Marco Cavallo

and

Juan Esteban Kamienkowski

submission deadline 23 Feb 2026 | 3 articles | Viewed by 8979 | Submission Open

Keywords: gaze patterns; eye tracking; mild cognitive impairment; multiple sclerosis; neurodevelopmental disorders; saccades

(This special issue belongs to the Section Behavioral Neuroscience)

Advances in Pediatric Neurological Disease Research

edited by Milena La Spina and

Silvia Marino

submission deadline 25 Feb 2026 | 1 articles | Viewed by 1085 | Submission Open

Keywords: non-invasive ventilation; ultrasound; epilepsy; CNS infection; neuro-oncology; genetic disease; sindromology; polysomnography

(This special issue belongs to the Section Developmental Neuroscience)

Current Advances in Developmental Dyslexia

edited by

John F. Stein

submission deadline 25 Feb 2026 | 1 articles | Viewed by 1083 | Submission Open

Keywords: developmental dyslexia; neuroimaging; neuropsychology; molecular genetics

(This special issue belongs to the Section Neurolinguistics)

Prenatal and Perinatal Risk Factors for Autism

edited by Gary Steinman

submission deadline 25 Feb 2026 | Viewed by 163 | Submission Open

Keywords: perinatal period; prenatal infection; children born preterm; pregnancy; autism

(This special issue belongs to the Section Developmental Neuroscience)

Lucid Dreaming and Psychophysiological Correlates of States of Consciousness

edited by

Daniel Erlacher

and Clarita Bonamino

submission deadline 27 Feb 2026 | 1 articles | Viewed by 2789 | Submission Open

Keywords: lucid dreaming; states of consciousness; REM sleep; metacognition; dream phenomenology; volitional control

(This special issue belongs to the Section Neuropsychology)

Mental Images and the Brain: From Cognitive Neuropsychology to Functional Neuroimaging

edited by

Anna Maria Berardi

submission deadline 27 Feb 2026 | Viewed by 230 | Submission Open

Keywords: mental imagery; visual perception; dorsal visual stream; ventral visual stream; object; spatial; brain lesion; functional brain imaging; aphantasia; hyperphantasia

(This special issue belongs to the Section Neuropsychology)

Neuromuscular Diseases and Musculoskeletal Disorders

edited by

Anna Christakou

submission deadline 28 Feb 2026 | 2 articles | Viewed by 9970 | Submission Open

Keywords: neuromuscular diseases; osteoporosis; fractures; muscle weakness; muscle intolerance; shoulder dysfunction; myopathy; physiotherapy; rehabilitation

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Biomarkers in Neurodegenerative Diseases: Advancements and Future Directions

edited by Fausto Roveta

submission deadline 28 Feb 2026 | 3 articles | Viewed by 8080 | Submission Open

Keywords: Alzheimer’ s disease; Parkinson’ s disease; neurodegenerative disorders; biomarkers; neuroimaging

(This special issue belongs to the Section Neurodegenerative Diseases)

Non-Invasive Brain Stimulation for Brain Disorders

edited by

Giovanni Cirillo

submission deadline 28 Feb 2026 | 1 articles | Viewed by 1975 | Submission Open

Keywords: TMS; tCS; NIBS; plasticity; CNS; neurological disorders; psychiatric disorders

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Novel Techniques in Spine Neurosurgery

edited by Maurizio Fornari,

Cesare Faldini

and Gabriele Capo

submission deadline 28 Feb 2026 | 2 articles | Viewed by 1563 | Submission Open

Keywords: spine neurosurgery; minimally invasive spine surgery; spinal endoscopy; robotic-assisted spine surgery; spinal navigation; augmented reality in neurosurgery; biologics and spinal fusion; neuromodulation; novel surgical techniques; technological innovation in spine surgery

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Cellular and Molecular Mechanisms Underlying Aging Progression

edited by

Mateus Vidigal de Castro

submission deadline 28 Feb 2026 | 1 articles | Viewed by 782 | Submission Open

Keywords: neuroaging ; neurodegeneration ; iPSC-derived models ; omics technologies ; cellular senescence ; neuroinflammation ; longevity

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Anxiety and Mood Disorders: Novel Research on Mechanisms, Diagnosis, and Treatment

edited by

Zuleide Maria Ignácio

submission deadline 28 Feb 2026 | 1 articles | Viewed by 533 | Submission Open

Keywords: anxiety disorders; mood disorders; neurotransmission; genetic and epigenetic mechanisms; therapeutic strategies; pharmacological targets; cellular circuits and signaling; neuronal plasticity; inflammation; oxidative stress

(This special issue belongs to the Section Neuropsychiatry)

Headache: Advances in Pathophysiology, Clinical Presentations and Therapeutic Options

edited by

Alessandro Viganò

submission deadline 28 Feb 2026 | Viewed by 397 | Submission Open

Keywords: migraine; comorbidities; pathophysiology; pharmacological interventions; non-pharmacological interventions; mechanisms

(This special issue belongs to the Section Systems Neuroscience)

Advances in Neuroinflammation and Immune Response

edited by Bojan Shutinoski

submission deadline 28 Feb 2026 | Viewed by 284 | Submission Open

Keywords: neuroinflammation; immune response; glial cells; blood– brain barrier; neurodegenerative diseases

(This special issue belongs to the Section Systems Neuroscience)

Application of Invasive and Non-Invasive Brain Stimulation Techniques in Neurological Disorders

edited by Vincenzo Levi and

Massimo Marano

submission deadline 10 Mar 2026 | 2 articles | Viewed by 2277 | Submission Open

Keywords: deep brain stimulation (DBS); magnetic resonance-guided focused ultrasound (MRgFUS); transcranial magnetic stimulation (TMS); transcranial direct-current stimulation (tDCS); vagus nerve stimulation (VNS); brain– machine interface; brain stimulation; non-invasive brain stimulation

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Unraveling the Role of Physical Activity in Brain, Cognition, and Mental Health

edited by

Fiorenzo Moscatelli

, Nicola Mancini and Pompilio Cusano

submission deadline 15 Mar 2026 | 4 articles | Viewed by 20216 | Submission Open

Keywords: physical activity; brain health; cognition; mental health; neurogenesis; neuroplasticity; cognitive function; exercise; depression; anxiety

(This special issue belongs to the Section Neuropsychiatry)

Current Basic and Clinical Approaches in Neurodegenerative Diseases: Diagnostics and Therapeutics

edited by

Genaro G. Ortiz

and Gloria A. Benítez-King

submission deadline 15 Mar 2026 | 3 articles | Viewed by 16156 | Submission Open

Keywords: neurodegenerative diseases; advances; diagnosis; treatment; basic clinical approach; treatment protocols

(This special issue belongs to the Section Neurodegenerative Diseases)

Non-Invasive Brain Stimulation in Neurological Diseases and Neurorehabilitation

edited by

Maryam Zoghi

submission deadline 15 Mar 2026 | 1 articles | Viewed by 3057 | Submission Open

Keywords: non-invasive brain stimulation; transcranial direct-current stimulation; transcranial magnetic stimulation; neurorehabilitation; neurological diseases; stroke; Parkinson's disease; multiple sclerosis; chronic pain

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Spinal Cord Injury: Biomarkers, Neuroimaging and Therapeutic Approaches

edited by

Alaa Abd-Elsayed

submission deadline 15 Mar 2026 | 2 articles | Viewed by 2468 | Submission Open

Keywords: spinal cord; injury; neuromodulation; surgery; injury; innovations

(This special issue belongs to the Section Neurorehabilitation)

EEG and fMRI Applications in Exploring Brain Activity

edited by

Nicoletta Cera

and Faustino Ricardo

submission deadline 15 Mar 2026 | 2 articles | Viewed by 1554 | Submission Open

Keywords: fMRI; EEG; resting state; data-driven analysis; machine learning; emotion; cognitive functions; aging; multimodal imaging

(This special issue belongs to the Section Neurotechnology and Neuroimaging)

Advances in Concussions

edited by

Neil Heron

submission deadline 15 Mar 2026 | Viewed by 123 | Submission Open

Keywords: concussion; mild traumatic brain injury; systematic review; concussion biomarkers; clinical trials; public health

(This special issue belongs to the Section Systems Neuroscience)

Neuromorphic Artificial Intelligence and Its Applications: Retrospective and Prospective

edited by Vassilis Cutsuridis

submission deadline 20 Mar 2026 | 3 articles | Viewed by 5954 | Submission Open

Keywords: neuromorphic artificial intelligence; deep learning; sensory recognition; cognitive function; cognitive robotics; neuroimaging

(This special issue belongs to the Section Computational Neuroscience, Neuroinformatics, and Neurocomputing)

Clinical Research on Neurological Rehabilitation After Stroke

edited by

Myoung-Kwon Kim

submission deadline 20 Mar 2026 | 2 articles | Viewed by 5591 | Submission Open

Keywords: stroke rehabilitation; neurological recovery; physical therapy; cognitive rehabilitation; neuroplasticity; functional outcomes; assistive technology; virtual reality therapy; Parkinson’ s disease rehabilitation

(This special issue belongs to the Section Neurorehabilitation)

Cellular and Molecular Mechanisms of Neuropathic Pain

edited by

Al-Khrasani Mahmoud

submission deadline 20 Mar 2026 | 2 articles | Viewed by 2183 | Submission Open

Keywords: neuropathic pain; mechanisms; novel targets; natural drugs; novel synthetic and semi-synthetic drugs; monoclonal antibodies

(This special issue belongs to the Section Sensory and Motor Neuroscience)

The Olfactory System in Health and Disease

edited by David M. Coppola

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1817 | Submission Open

Keywords: Alzheimer’ s; Parkinson’ s; Huntington’ s; MS; depression; anxiety; disorder; olfactory bulbectomy; anosmia; smell; limbic system

(This special issue belongs to the Section Systems Neuroscience)

The Role of Multimodal Imaging in Assessing the Biology and Staging of Neurodegenerative Disorders

edited by

Andrea Varrone

submission deadline 20 Mar 2026 | 1 articles | Viewed by 1408 | Submission Open

Keywords: amyloid beta; phosphorylated tau; alpha-synuclein; neuronal loss; neuromelanin; iron content; cardiac denervation; dopaminergic cell loss

(This special issue belongs to the Section Neurodegenerative Diseases)

Advances in Rehabilitation Strategies for Traumatic Brain Injury

edited by

Jennifer V. Wethe

submission deadline 20 Mar 2026 | Viewed by 246 | Submission Open

Keywords: traumatic brain injury; neurorehabilitation; neuroplasticity; cognitive rehabilitation; virtual reality; community reintegration; tele-rehabilitation; neurostimulation; translational research; individualized intervention

(This special issue belongs to the Section Neurorehabilitation)

Neurobehavioral Mechanisms of Learning and Adaptation: Translational Perspectives from Basic to Applied Science

edited by John Michael Falligant and

Rusty Nall

submission deadline 20 Mar 2026 | Viewed by 240 | Submission Open

Keywords: behavioral neuroscience; experimental analysis of behavior; computational behavior analysis; quantitative modeling; reinforcement learning; translational research; behavioral pharmacology; neurobehavioral mechanisms of learning; persistence and relapse; behavioral phenotyping

(This special issue belongs to the Section Behavioral Neuroscience)

Intracranial Aneurysms: What Do We Know So Far?

edited by Alessio Albanese and Giuseppe Esposito

submission deadline 20 Mar 2026 | Viewed by 148 | Submission Open

Keywords: intracranial aneurysms; clipping; endovascular therapy; stenting; coiling; cerebral vasospasm; cerebrovascular diseases; microneurosurgery; subarachnoid hemorrhage; bypass

(This special issue belongs to the Section Neurosurgery and Neuroanatomy)

Inflammation, Stress, and Comorbidity in Psychiatry: Mechanisms and Therapeutic Implications

edited by Heline Mirzakhanian

submission deadline 20 Mar 2026 | Viewed by 147 | Submission Open

Keywords: immune biomarkers in psychiatry; neuroinflammation; precision neuropsychiatry; risk mechanisms; comorbidity models; HPA axis dysregulation; anti-inflammatory treatments; psychiatric and physical comorbidity; cytokine signaling; microglial activation

(This special issue belongs to the Section Neuropsychiatry)

Neural Correlates of Cognitive Workload and Learning: Portable Brain Monitoring During Skill Acquisition and Real-World Task Performance

edited by Adrian Curtin, Sebastien Scannella,

Hasan Ayaz

and

Candida Barreto

submission deadline 25 Mar 2026 | 1 articles | Viewed by 1546 | Submission Open

Keywords: portable neuroimaging; wearable brain sensing; skill acquisition; expertise development; motor learning; cognitive workload; fNIRS/EEG applications; neural efficiency; closed-loop training; neurostimulation (tDCS/rTMS/FUS)

(This special issue belongs to the Section Neural Engineering, Neuroergonomics and Neurorobotics)

Balance: Multisensory Integration and Rehabilitation Approaches

edited by

Min-wook Kim

submission deadline 25 Mar 2026 | Viewed by 230 | Submission Open

Keywords: multisensory integration; balance and gait disorders; vestibular; visual; and somatosensory assessment; postural control; sensorimotor dysfunction; neurodegenerative diseases (e.g.; Parkinson’ s; PSP); stroke and brain injury; motor rehabilitation; virtual and augmented reality; neuroplasticity; fall risk and prevention; wearable technology and kinematic analysis

(This special issue belongs to the Section Neurodegenerative Diseases)

Language Perception and Processing

edited by

Ratree Wayland

submission deadline 27 Mar 2026 | 11 articles | Viewed by 10067 | Submission Open

Keywords: language; cognitive mechanism; neural mechanism; speech; perception; processing

(This special issue belongs to the Section Neurolinguistics)

Neuropsychological Exploration of Spatial Cognition and Navigation

edited by

Jose Manuel Cimadevilla

Laura Piccardi

Raffaella Nori

Maria Kozhevnikov

and Sean Commins

submission deadline 27 Mar 2026 | 5 articles | Viewed by 6101 | Submission Open

Keywords: spatial memory; neuropsychological; spatial navigation; cognitive disorder; Alzheimer’ s disease; spatial cognition; dementia; brain Function

(This special issue belongs to the Section Neuropsychology)

Palliative Care for Patients with Severe Neurological Impairment

edited by

Giovanna Artioli

and

Federica Dellafiore

submission deadline 30 Mar 2026 | 4 articles | Viewed by 6441 | Submission Open

Keywords: severe neurological impairment; neurological chronic disease; palliative care; early palliative care; nursing competencies; advance care planning; caregiver support; mental Illness of Healthcare professionals; non pharmacological and complementary treatment; bio-psyco-social and existential needs of patient and caregiver

(This special issue belongs to the Section Neurorehabilitation)

Editorial Board Collection Series: Innovative Research in Molecular and Cellular Neuroscience for Regulation of Cell Death Mechanisms for Functional Neuroprotection

edited by

Swapan K. Ray

submission deadline 31 Mar 2026 | 4 articles | Viewed by 5750 | Submission Open

Keywords: apoptosis; autophagy; artificial intelligence; CRISPR; demyelination; ferroptosis; inflammasomes; microRNAs; necrosis; neuroprotection; organoids; PANoptosis; animal and cellular models of neurological diseases and injuries; proteases

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Advances in LRRK2 and Other Pathological Mechanisms of Parkinson's Disease

edited by

Dong Hwan Ho

submission deadline 31 Mar 2026 | 1 articles | Viewed by 4203 | Submission Open

Keywords: Parkinson's disease; leucine-rich repeat kinase 2; dopaminergic neuronal death; neurodegenerative disease; neuroinflammation; neuroprotection

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Burnout, Adjustment Disorder and Post-Traumatic Stress Disorder: Risk Factors, Impact, Preventive Strategies and Treatment Options

edited by

Martina Corsi

and

Rudy Foddis

submission deadline 31 Mar 2026 | 2 articles | Viewed by 3017 | Submission Open

Keywords: burnout; AD; PTSD; psychosocial risk; AI; prevention; diagnosis; treatment

(This special issue belongs to the Section Systems Neuroscience)

Research Progress on the Pathogenesis, Diagnosis and Treatment of Parkinson Disease

edited by Giulia Carli and Prabesh Kanel

submission deadline 31 Mar 2026 | 1 articles | Viewed by 2586 | Submission Open

Keywords: Parkinson’ s disease; Lewy bodies diseases; disease progression; clinical heterogeneity; preclinical and prodromal stages; treatments; comorbidities

(This special issue belongs to the Section Neurodegenerative Diseases)

Dementia and Cognitive Decline in Aging

edited by

Yvonne Leung

submission deadline 31 Mar 2026 | 3 articles | Viewed by 2506 | Submission Open

Keywords: dementia; cognitive impairment; Alzheimer’ s disease; mild cognitive impairment (MCI); neurodegeneration; cognitive aging; biomarkers; cognitive resilience; cognitive reserve

(This special issue belongs to the Section Cognitive, Social and Affective Neuroscience)

Psychiatry and Addiction: A Multi-Faceted Issue—2nd Edition

edited by

Fabrizio Schifano

Norbert Scherbaum

and

Giovanni Martinotti

submission deadline 31 Mar 2026 | 1 articles | Viewed by 956 | Submission Open

Keywords: addiction spectrum disorders; substance misuse; dual disorders; alcohol misuse; prescription drug misuse; dopamine; neurotransmitter pathways; reward systems; addiction treatment; reward deficit syndrome; translational anti-craving medications; food addiction; sex addiction; internet gaming disorder; gambling; novel antidiabetics; salience; novel psychoactive substances (NPSs); prescription drug misuse; brain– gut axis; microbiome

(This special issue belongs to the Section Behavioral Neuroscience)

Plasticity of Sensory Cortices: From Basic to Clinical Research

edited by Stephanie Clarke and Sonia Crottaz-Herbette

submission deadline 31 Mar 2026 | 1 articles | Viewed by 852 | Submission Open

Keywords: tonotopy; retinotopy; somatotopy; vestibular; olfactory; gustatory; training-induced plasticity; postlesional plasticity; cochlear implant; prostheses

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Neuroimmune Crosstalk in Neurological Disorders: Mechanistic Insights to Therapeutic Interventions

edited by

Ansab Akhtar

submission deadline 31 Mar 2026 | 1 articles | Viewed by 454 | Submission Open

Keywords: neuroinflammation; neuroimmune system; glial cell dynamics; immune cell trafficking; cyto-kine signaling; neurological disorders; immune modulation

(This special issue belongs to the Section Molecular and Cellular Neuroscience)

Emerging Trends and Perspectives in the Neuroscience of Pain

edited by Martina Rekatsina and

Panagiotis Zis

submission deadline 31 Mar 2026 | Viewed by 266 | Submission Open

Keywords: neuroscience of pain; neuroimaging techniques; neuromodulation therapies; pain mechanisms; chronic pain

(This special issue belongs to the Section Sensory and Motor Neuroscience)

Shaping the Brain in Sleep: Neurodevelopmental Mechanisms Across the Lifespan

edited by Sally Staton, Jasneek Chawla and Kartik Iyer

submission deadline 31 Mar 2026 | Viewed by 173 | Submission Open

Keywords: sleep; brain development; neurodevelopment; sensitive periods; napping; genetic and environmental influences; early childhood; adolescents; adulthood; lifespan development

(This special issue belongs to the Section Sleep and Circadian Neuroscience)

Advances in Immune-Mediated Disorders of the Nervous System in Childhood

edited by Martino Ruggieri and

Andrea Domenico Praticò

submission deadline 10 Apr 2026 | 1 articles | Viewed by 755 | Submission Open

Keywords: autoimmune encephalitis; pediatric neuroinflammation; immune-mediated CNS disorders; childhood multiple sclerosis; MOG antibody disease; neuroimmunology; immunotherapy in children; neuromyelitis optica

(This special issue belongs to the Section Developmental Neuroscience)

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