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Diagnostics, Volume 15, Issue 10

2025 May-2 - 117 articles

Cover Story: Basal cell carcinoma (BCC) is the most common keratinocytic malignant tumor that affects sun exposure areas, especially in the head-and-neck region. Early diagnosis can limit the extent of facial tissue involvement and subsequent resection, resulting in improved cosmetic and functional results. In vivo reflectance confocal microscopy (RCM) is a non-invasive imaging technique of high diagnostic value used to support the early diagnosis of BCC. The aim of this study was to provide the largest and most up-to-date overview of ocular and periocular BCCs. We also reported the first case of caruncle BCC investigated by dermoscopy and RCM. A systematic review and meta-analysis were carried out, including 236 articles encompassing a total of 71,730 patients with ocular and periocular BCCs. View this paper
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Articles (117)

  • Article
  • Open Access
1,907 Views
12 Pages

Background/Objectives: One of the surgical treatments for lumbar foraminal stenosis, full endoscopic foraminotomy, is known for its numerous advantages and favourable clinical outcomes. While previous studies have analyzed preoperative radiological r...

(This article belongs to the Special Issue Recent Advances in Bone and Joint Imaging—2nd Edition)
  • Article
  • Open Access
1 Citations
1,917 Views
12 Pages

The Train-Line Pattern on Duplex Ultrasound Helps Differentiate Intramural Thrombus from Atheromatous Plaque in Common Carotid Artery Dissection

  • Ming-Hsing Chang,
  • Yen-Yu Huang,
  • Fang-I Hsieh,
  • Kuan-Yu Lin and ,
  • Hsu-Ling Yeh,
  • Kai-Jing Yeh and
  • Li-Ming Lien
  • + 2 authors+ 0 author

Background/Objectives: Common carotid artery dissection (CCAD) can result in severe neurological sequelae; however, its diagnosis may be challenging due to consciousness disturbance and aphasia. The objective of this article is to propose a new imagi...

(This article belongs to the Special Issue Neurological Disorders: Diagnosis and Management)
  • Article
  • Open Access
1,486 Views
16 Pages

Diagnostic Utility of Podoplanin Immunohistochemistry Combined with the NanoSuit-Correlative Light and Electron Microscopy Method for Thoracic Malignant Tumors

  • Shin-ya Katsuragi,
  • Yuri Sakano,
  • Isao Ohta,
  • Hisami Kato and ,
  • Rei Ishikawa,
  • Hirofumi Watanabe,
  • Ryosuke Miyazaki,
  • Katsuhiro Yoshimura,
  • Hidetaka Yamada and
  • Kazuya Shinmura
  • + 12 authors+ 7 authors

Background/Objectives: Differentiating thoracic malignant tumors, such as epithelioid malignant pleural mesothelioma (EMPM) and non-small-cell lung carcinoma (NSCLC), primarily comprising lung adenocarcinoma (LAC) and lung squamous cell carcinoma (LS...

(This article belongs to the Special Issue Diagnosis, Classification, and Monitoring of Pulmonary Diseases)
  • Article
  • Open Access
1 Citations
1,399 Views
16 Pages

Paramedics Performed Sonographic Identification of the Conic Ligament—A Prospective Controlled Trial

  • Johannes Weimer,
  • Christopher David Chrissostomou,
  • Christopher Jonck,
  • Andreas Michael Weimer and ,
  • Carlotta Ille,
  • Lukas Müller,
  • Liv Annebritt Lorenz,
  • Marie Stäuber,
  • Thomas Vieth and
  • Julian Künzel
  • + 8 authors+ 3 authors

Background/Objectives: Acute obstructions of the upper respiratory tract are emergencies that may require a cricothyrotomy as ultima ratio. For this, precise identification of the conic ligament is essential. Point-of-care ultrasound (POCUS) offers a...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
2 Citations
3,227 Views
24 Pages

Utility of Biometric Measurements from Fetal Magnetic Resonance Imaging for Improved Antenatal Diagnosis of Dandy–Walker Spectrum Posterior Fossa Lesions

  • Rakhee M. Bowker,
  • Kranthi K. Marathu,
  • Marissa Pharel,
  • Jubril O. Adepoju and ,
  • Farzan Vahedifard,
  • Seth Adler,
  • Mehmet Kocak,
  • Xuchu Liu and
  • Sharon E. Byrd
  • + 4 authors+ 0 author

Background/Objective: The accurate diagnosis of congenital central nervous system abnormalities is critical to pre- and postnatal prognostication and management. When an abnormality is found in the posterior fossa of the fetal brain, parental counsel...

(This article belongs to the Special Issue Advances in Fetal Imaging)
  • Review
  • Open Access
2 Citations
3,296 Views
27 Pages

Forensic Microbiology: Challenges in Detecting Sexually Transmitted Infections

  • Ana Eira,
  • Jennifer Fadoni,
  • António Amorim and
  • Laura Cainé

Sexual assault crimes consist of acts committed without consent and represent a major global issue with serious implications for victims. These acts have both short- and long-term consequences on the physical, mental, and sexual health of victims, wi...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
2 Citations
10,756 Views
11 Pages

Comparative Evaluation of Four Different Anti-CCP Assays for the Diagnosis of Rheumatoid Arthritis: A Diagnostic Performance Analysis

  • Lydia Lamara Mahammed,
  • Tamazouzt Hadjout,
  • Asma Bensaci,
  • Ryma Hamma and ,
  • Ghalya Bousbia,
  • Nawel Dahmani,
  • Halima Ismail,
  • Nadia Tamechmacht and
  • Reda Djidjik
  • + 4 authors+ 0 author

Background/Objectives: Anti-cyclic citrullinated peptide (anti-CCP) antibodies are highly specific markers for rheumatoid arthritis (RA). Over the past decade, novel automating detection systems have been developed for anti-CCP detection. The present...

(This article belongs to the Section Clinical Laboratory Medicine)
  • Article
  • Open Access
9 Citations
3,616 Views
13 Pages

Radiomics and AI-Based Prediction of MGMT Methylation Status in Glioblastoma Using Multiparametric MRI: A Hybrid Feature Weighting Approach

  • Erdal Tasci,
  • Ying Zhuge,
  • Longze Zhang,
  • Holly Ning and ,
  • Jason Y. Cheng,
  • Robert W. Miller,
  • Kevin Camphausen and
  • Andra V. Krauze
  • + 3 authors+ 0 author

Background/Objectives: Glioblastoma (GBM) is a highly aggressive primary central nervous system tumor with a median survival of 14 months. MGMT (O6-methylguanine-DNA methyltransferase) promoter methylation status is a key biomarker as a prognostic in...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
3 Citations
2,060 Views
12 Pages

Effect of Strabismus Surgery on Meibomian Glands, Ocular Surface Parameters, and Conjunctival Impression Cytology

  • Şenol Sabancı,
  • Canan Sadullahoğlu,
  • Sibel Yavuz,
  • Mehmet Fatih Küçük and ,
  • Esra Kızıldağ Özbay,
  • Muhammet Kazım Erol and
  • Berna Doğan
  • + 2 authors+ 0 author

Background/Objectives: To investigate the effect of strabismus surgery on ocular surface parameters, meibomian glands, and conjunctival impression cytology. Methods: Preoperative and postoperative (10th day, first month, and third month) tear break-u...

(This article belongs to the Section Clinical Diagnosis and Prognosis)
  • Article
  • Open Access
1,656 Views
9 Pages

Post Mortem Paliperidone Blood Concentrations Following Long-Acting Injectable Treatments

  • Pietro Zuccarello,
  • Giulia Carnazza,
  • Antonino Petralia and
  • Nunziata Barbera

Background/Objectives: I Paliperidone is an antipsychotic recently added into the market in various formulations. There are few data about safety and on therapeutic, toxic, or lethal blood concentrations. Currently, the published analytical methods a...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Review
  • Open Access
7 Citations
4,597 Views
17 Pages

The Application of Circulating Tumour DNA (ctDNA) in the Diagnosis, Prognosis, and Treatment Monitoring of Gynaecological and Breast Cancers (Review)

  • Aleksandra Englisz,
  • Marta Smycz-Kubańska,
  • Patrycja Królewska-Daszczyńska,
  • Magdalena Błaut and ,
  • Agnieszka Duszyc and
  • Aleksandra Mielczarek-Palacz
  • + 1 author+ 0 author

Gynaecological cancers, including endometrial, ovarian, and cervical cancers as well as breast cancer, despite numerous studies, still constitute a challenge for modern oncology. For this reason, research aimed at the application of modern diagnostic...

(This article belongs to the Special Issue Diagnosis and Management of Gynecological Cancers: Third Edition)
  • Article
  • Open Access
2 Citations
2,932 Views
11 Pages

Diagnostic Value of Multimodal Lymphatic Imaging Techniques in Thoracic Duct Outlet Obstruction

  • Ying Fei,
  • Yanli Lu,
  • Zhichao Yao,
  • Kongxiang Yin and ,
  • Dayong Zhou and
  • Zhanao Liu
  • + 1 author+ 0 author

Objectives: To investigate the diagnostic value of various lymphatic imaging techniques for thoracic duct (TD) outlet obstruction in patients with chylous leakage. Methods: A retrospective analysis was conducted on 23 patients with chylous leakage wh...

(This article belongs to the Special Issue New Advances in Thoracic Surgery: Clinical Diagnosis, Treatment, and Prognosis)
  • Article
  • Open Access
1 Citations
1,465 Views
17 Pages

Immune Cells as Mediators of Lipidome Influence on Osteoporosis: Evidence from a Mediation Analysis

  • Jiheng Xiao,
  • Wei Zhou,
  • Jiatai He,
  • Yanbin Zhu and ,
  • Yingze Zhang and
  • Liming Xiong
  • + 1 author+ 0 author

Background: Although clinical studies have indicated a possible association between dyslipidemia and osteoporosis, the underlying genetic basis and mechanistic pathways remain insufficiently defined. Most prior research has concentrated on convention...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
3 Citations
4,038 Views
16 Pages

Sexual Functioning and Depressive Symptoms in Women with Postpartum Thyroiditis

  • Karolina Kowalcze,
  • Gaspare Cucinella,
  • Giuseppe Gullo and
  • Robert Krysiak

Background/Objectives: The presence of autoimmune thyroiditis was found to be associated with an increased prevalence of sexual dysfunction. Women’s sexual health was not investigated in postpartum disorders of the thyroid gland. The aim of thi...

(This article belongs to the Special Issue Diagnosis and Prognosis of Gynecological and Obstetric Diseases)
  • Article
  • Open Access
12 Citations
5,965 Views
28 Pages

Multiclassification of Colorectal Polyps from Colonoscopy Images Using AI for Early Diagnosis

  • Jothiraj Selvaraj,
  • Kishwar Sadaf,
  • Shabnam Mohamed Aslam and
  • Snekhalatha Umapathy

Background/Objectives: Colorectal cancer (CRC) remains one of the leading causes of cancer-related mortality worldwide, emphasizing the critical need for the accurate classification of precancerous polyps. This research presents an extensive analysis...

(This article belongs to the Special Issue Lesion Detection and Analysis Using Artificial Intelligence, Third Edition)
  • Article
  • Open Access
2,010 Views
10 Pages

The Clinical and Laboratory Profiles of a Deletional α2-Globin Gene Polyadenylation Signal Sequence (AATAAA > AATA--) [HBA2:c.*93_*94delAA]: The Malaysian Experience

  • Norafiza Mohd Yasin,
  • Syahzuwan Hassan,
  • Nur Aisyah Aziz,
  • Faidatul Syazlin Abdul Hamid and ,
  • Ezalia Esa,
  • Ezzanie Suffya Zulkefli,
  • Rohana Ghazali,
  • Syirah Nazirah Tajuddin,
  • Mohd Nazif Darawi and
  • Cornelis L. Harteveld
  • + 6 authors+ 1 author

Poly A (AATAAA > AATA--) [HBA2:c.*93_*94delAA] is a rare α-variant reported in our population. It is caused by 2 bp deletion (--AA) in the α2 poly A sequence, leading to a significant α–thalassaemia phenotype. Background/Ob...

(This article belongs to the Section Clinical Laboratory Medicine)
  • Article
  • Open Access
1 Citations
2,221 Views
16 Pages

Background/Objectives: This study aimed to investigate whether small-cell lung cancer (SCLC) and non-small-cell lung cancer (NSCLC) can be distinguished based on radiomics data derived from T2-FLAIR digital subtraction images of the peritumoral edema...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Systematic Review
  • Open Access
2 Citations
2,957 Views
14 Pages

Efficacy of Hyperosmolar Dextrose Injection for Osgood–Schlatter Disease: A Systematic Review with Meta-Analysis

  • Hye Chang Rhim,
  • Lori B. Bjork,
  • Jaehyung Shin,
  • Jewel Park and ,
  • Stephanie E. DeLuca,
  • Katelyn C. McCarron,
  • Ki-Mo Jang and
  • Chris Ha
  • + 3 authors+ 0 author

Background/Objectives: Although Osgood–Schlatter disease (OSD) is often self-limiting following apophyseal closure, it may cause persistent symptoms into adulthood, affecting physical and functional activities. The purpose of this systematic re...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
1 Citations
1,396 Views
14 Pages

Association of [18F]-FDG PET/CT-Derived Radiomic Features with Clinical Outcomes and Genomic Profiles in Patients with Chronic Lymphocytic Leukemia

  • Fabiana Esposito,
  • Luigi Manco,
  • Guglielmo Manenti,
  • Livio Pupo and ,
  • Andrea Nunzi,
  • Roberta Laureana,
  • Luca Guarnera,
  • Massimiliano Marinoni,
  • Elisa Buzzatti and
  • Maria Ilaria Del Principe
  • + 10 authors+ 5 authors

Background: The role of PET/CT imaging in chronic lymphoproliferative syndromes (CLL) is debated. This study examines the potential of PET/CT radiomics in predicting outcomes and genetic profiles in CLL patients. Methods: A retrospective analysis was...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Interesting Images
  • Open Access
1,570 Views
3 Pages

Tumor cavitation is distinguished by the emergence of central necrosis and cavity formation within the tumor mass, which indicates a notable outcome of anti-angiogenic therapies. This case describes a 52-year-old Chinese female with advanced EGFR-mut...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
2 Citations
1,757 Views
18 Pages

Experience in Diagnostic of HIV Drug Resistance in the Mekong Delta Region, Vietnam: A Comparative Analysis Before and After the COVID-19 Pandemic

  • Huynh Hoang Khanh Thu,
  • Alexandr N. Schemelev,
  • Yulia V. Ostankova,
  • Vladimir S. Davydenko and ,
  • Diana E. Reingardt,
  • Ton Tran,
  • Le Chi Thanh,
  • Thi Xuan Lien Truong and
  • Areg A. Totolian
  • + 4 authors+ 0 author

Background: Vietnam has made significant strides in reducing the prevalence of HIV infection and achievements in its antiretroviral treatment program. However, the COVID-19 pandemic and financial challenges in the healthcare system have posed signifi...

(This article belongs to the Section Diagnostic Microbiology and Infectious Disease)
  • Article
  • Open Access
4 Citations
1,865 Views
19 Pages

Background: Arteriovenous fistula (AVF) failure rates are consistently higher in females, although the underlying mechanisms remain incompletely understood. Inflammatory processes play a key role in AVF remodeling and venous arterialization, yet thei...

(This article belongs to the Section Clinical Laboratory Medicine)
  • Article
  • Open Access
1 Citations
3,017 Views
11 Pages

First-Trimester Morphological Evaluation of Fetuses and Medical Law Implications

  • Răzvan Grigoraș Căpitănescu,
  • Marius Cristian Marinaș,
  • Larisa Pătru,
  • Dragoș George Popa and ,
  • Elena Cristina Andrei,
  • Aura Iuliana Popa,
  • Gabriel Florin Răzvan Mogoș,
  • Nicolae Dragoș Mărgăritescu and
  • Ciprian Laurențiu Pătru
  • + 4 authors+ 0 author

Background/Objectives: Over the years, the potential of the first-trimester (FT) ultrasound in the detection of fetal structural defects has increased. The main objectives of the first-trimester fetal screening evaluation are the detection of major s...

(This article belongs to the Special Issue Echocardiography Applications in Cardiovascular Diseases)
  • Article
  • Open Access
4 Citations
3,390 Views
16 Pages

Artificial Intelligence as a Potential Tool for Predicting Surgical Margin Status in Early Breast Cancer Using Mammographic Specimen Images

  • David Andras,
  • Radu Alexandru Ilies,
  • Victor Esanu,
  • Stefan Agoston and ,
  • Tudor Florin Marginean Jumate and
  • George Calin Dindelegan
  • + 1 author+ 0 author

Background/Objectives: Breast cancer is the most common malignancy among women globally, with an increasing incidence, particularly in younger populations. Achieving complete surgical excision is essential to reduce recurrence. Artificial intelligenc...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Case Report
  • Open Access
1 Citations
2,288 Views
13 Pages

Carotid Stump Syndrome: A Case That Highlights the Necessity of Digital Subtraction Angiography for the Prompt Management of the Syndrome

  • Christos Stenos,
  • Aikaterini Anastasiou,
  • Georgia Nikolopoulou,
  • Panagiotis Papanagiotou and ,
  • Georgios Papagiannis,
  • Aikaterini Koutroumpi,
  • Danai Drakopoulou,
  • Periklis Anastasiou and
  • Konstantina Yiannopoulou
  • + 4 authors+ 0 author

Background and Clinical Significance: Carotid stump syndrome (CSS) is a rare and unexpected cause of recurrent ischemic ipsilateral events in the carotid vascular territory despite the demonstrated occlusion of the internal carotid artery (ICA). It i...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
1,072 Views
13 Pages

Background: Left ventricular ejection fraction remains the primary focus in cardiac monitoring for oncology patients undergoing potentially cardiotoxic chemotherapy, while right ventricular function is seldom examined. This study evaluates how establ...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
1 Citations
1,424 Views
10 Pages

Outcomes and Prognostic Markers in Extracorporeal Cardiopulmonary Resuscitation: 10-Year Experience from a Rural Tertiary Care Center

  • Kamran Namjouyan,
  • Aastha Mittal,
  • Evan Gajkowski,
  • Amanda Young and ,
  • Sudheer Penupolu and
  • Brendan Carry
  • + 1 author+ 0 author

Background: Extracorporeal cardiopulmonary resuscitation (eCPR) is a method for initiation of cardiopulmonary bypass during resuscitation of a patient with refractory cardiac arrest to support end-organ perfusion. This retrospective study evaluates w...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Review
  • Open Access
7 Citations
6,411 Views
18 Pages

Utility and Challenges of Imaging in Peripheral Vestibular Disorder Diagnosis: A Narrative Review

  • Gabriela Cornelia Musat,
  • Codrut Sarafoleanu,
  • Mihai Alexandru Preda,
  • Calin Petru Tataru and ,
  • George G. Mitroi,
  • Andreea Alexandra Mihaela Musat,
  • Mihnea Radu and
  • Ovidiu Musat
  • + 3 authors+ 0 author

This review focuses on the contribution of medical imaging in the diagnosis of peripheral vestibular disorders. This is a narrative review based on a focused literature search conducted using PubMed and the Cochrane Library. Imaging is not usually re...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
12 Citations
3,239 Views
22 Pages

Comparative Study of Cell Nuclei Segmentation Based on Computational and Handcrafted Features Using Machine Learning Algorithms

  • Rashadul Islam Sumon,
  • Md Ariful Islam Mozumdar,
  • Salma Akter,
  • Shah Muhammad Imtiyaj Uddin and ,
  • Mohammad Hassan Ali Al-Onaizan,
  • Reem Ibrahim Alkanhel and
  • Mohammed Saleh Ali Muthanna
  • + 2 authors+ 0 author

Background: Nuclei segmentation is the first stage of automated microscopic image analysis. The cell nucleus is a crucial aspect in segmenting to gain more insight into cell characteristics and functions that enable computer-aided pathology for early...

(This article belongs to the Special Issue Diagnostic Imaging of Prostate Cancer)
  • Review
  • Open Access
2 Citations
8,175 Views
17 Pages

Vulvar Hemangioma: A Review

  • Wing-Yu Sharon Siu,
  • Yen-Chang Chen and
  • Dah-Ching Ding

Objectives: To review the clinical presentation, diagnostic approach, treatment strategies, and outcomes of vulvar hemangiomas, and to evaluate the consistency of management practices in the absence of standardized guidelines. Eligibility criteria: W...

(This article belongs to the Section Clinical Diagnosis and Prognosis)
  • Article
  • Open Access
3 Citations
1,415 Views
12 Pages

Unsupervised Clustering of Patients Undergoing Thoracoscopic Ablation Identifies Relevant Phenotypes for Advanced Atrial Fibrillation

  • Ilse Meijer,
  • Marc M. Terpstra,
  • Oscar Camara,
  • Henk A. Marquering and ,
  • Nerea Arrarte Terreros and
  • Joris R. de Groot
  • + 1 author+ 0 author

Background/Objectives: The rate of recurrence after ablation for atrial fibrillation (AF) is considerable. Risk stratification for AF recurrence after ablation remains incompletely developed. Unsupervised clustering is a machine learning technique wh...

(This article belongs to the Special Issue Diagnosis and Management of Arrhythmias)
  • Article
  • Open Access
5 Citations
2,389 Views
20 Pages

Background/Objectives: Nonverbal synchrony—the temporal coordination of physical behaviors such as head movement and gesture—is a critical component of effective social communication. Individuals with autism spectrum disorder (ASD) are of...

(This article belongs to the Section Clinical Diagnosis and Prognosis)
  • Case Report
  • Open Access
5 Citations
4,185 Views
15 Pages

Fibrotic Hypersensitivity Pneumonitis: A Diagnostic Challenge Leading to Lung Transplantation

  • Maria-Daniela Mot,
  • Dana Cristina Olar,
  • Paula Alexandra Vulciu,
  • Paula-Irina Barata and ,
  • Ana-Liana Bouros-Tataru,
  • Denis Bogdan Butari,
  • Florin Mihai Șandor and
  • Laura Ioana Bondar
  • + 3 authors+ 0 author

Background/Objectives: Hypersensitivity pneumonitis (HP), a subtype of interstitial lung disease (ILD), is often misdiagnosed as idiopathic pulmonary fibrosis (IPF), particularly when the causative antigen cannot be identified. Typically resulting fr...

(This article belongs to the Special Issue Diagnosis of Cardio-Thoracic Diseases)
  • Article
  • Open Access
3 Citations
1,803 Views
11 Pages

Purpose: This study aimed to evaluate the efficacy and safety of the Angio-Seal™ VIP vascular closure device (VCD) in achieving hemostasis following percutaneous transhepatic portal venous interventions. Methods: This retrospective study evalua...

(This article belongs to the Special Issue Advancements in Interventional Radiology Techniques in Vascular and Extravascular Diseases)
  • Case Report
  • Open Access
2 Citations
2,723 Views
10 Pages

Background/Objectives: Among the various types of masses that can cause compression, hematomas are a relatively common but often overlooked cause. Rheumatoid arthritis (RA) is associated with bleeding problems due to vascular inflammation, platelet d...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
4 Citations
1,750 Views
26 Pages

The Effect of Lesion Length on Doppler Velocities Used Routinely to Determine Carotid Stenosis Cross-Sectional Severity

  • Wladyslaw Dabrowski,
  • Lukasz Tekieli,
  • Anna Kablak-Ziembicka,
  • Justyna Stefaniak and ,
  • Karolina Dzierwa,
  • Adam Mazurek,
  • Piotr Paluszek,
  • Krzysztof Zmudka,
  • Piotr Pieniazek and
  • Piotr Musialek
  • + 5 authors+ 0 author

Background/Objective: Transcutaneous Doppler ultrasound is a fundamental tool in evaluating carotid stenosis cross-sectional severity (CS-CSS) in clinical practice because peak-systolic and end-diastolic velocities (PSV, EDV) increase with angiograph...

(This article belongs to the Special Issue Advances in Ultrasound)
  • Systematic Review
  • Open Access
4 Citations
6,273 Views
19 Pages

The Association of Placental Grading with Perinatal Outcomes: A Systematic Review and Meta-Analysis

  • Antonios Siargkas,
  • Christina Pachi,
  • Meletios P. Nigdelis,
  • Sofoklis Stavros and ,
  • Ekaterini Domali,
  • Apostolos Mamopoulos,
  • Ioannis Tsakiridis and
  • Themistoklis Dagklis
  • + 3 authors+ 0 author

Objective: Premature placental calcification (PPC) has been implicated in adverse perinatal outcomes, yet its clinical significance remains controversial. This meta-analysis aimed to quantitatively synthesize current data on the association between P...

(This article belongs to the Special Issue Diagnosis and Management of Contemporary Issues in Maternal-Fetal Medicine)
  • Article
  • Open Access
4,547 Views
13 Pages

Incidental Calcifications of Carotid and Vertebral Arteries: Frequency and Associations in Pediatric Population

  • Turkhun Cetin,
  • Gokce Cinar,
  • Berna Ucan,
  • Fulya Memis and ,
  • Baris Irgul and
  • Sonay Aydin
  • + 1 author+ 0 author

Background: Calcifications in the carotid and vertebral arteries may be present on cranial and temporal bone CT imaging of pediatric patients. Few studies have investigated the frequency, location, and patterns of carotid artery calcifications in thi...

(This article belongs to the Special Issue Advances in the Diagnosis and Management of Pediatric Diseases)
  • Interesting Images
  • Open Access
1 Citations
1,528 Views
4 Pages

A 49-year-old female presented for nuclear medicine diagnostics of a sonographically suspected parathyroid adenoma dorsal to the cranial pole of the right thyroid lobe. The patient received Tc-99m-pertechnetate and Tc-99m-sestamibi (including SPECT/C...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Interesting Images
  • Open Access
1,213 Views
3 Pages

Greater Omentum Abscess Revealing an Upper Genital Infection

  • Romain L’Huillier and
  • Alexandra Braillon

In this clinical case, we report an upper genital infection revealed on Computed Tomography by a greater omentum abscess. The infection was confirmed by endocervical swabs and ultrasound-guided sampling of the epiploic abscess, which found the same b...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
7 Citations
2,656 Views
20 Pages

Investigating the Role of Intravoxel Incoherent Motion Diffusion-Weighted Imaging in Evaluating Multiple Sclerosis Lesions

  • Othman I. Alomair,
  • Sami A. Alghamdi,
  • Abdullah H. Abujamea,
  • Ahmed Y. AlfIfi and ,
  • Yazeed I. Alashban and
  • Nyoman D. Kurniawan
  • + 1 author+ 0 author

Background: Multiple sclerosis (MS) is a chronic and heterogeneous disease characterized by demyelination and axonal loss and damage. Magnetic resonance imaging (MRI) has been employed to distinguish these changes in various types of MS lesions. Obje...

(This article belongs to the Special Issue Neurological Diseases: Biomarkers, Diagnosis and Prognosis)
  • Article
  • Open Access
1 Citations
3,567 Views
13 Pages

Management of Postoperative Pancreatic Fluid Collection and Role of Endoscopy: A Case Series and Review of the Literature

  • Chiara Coluccio,
  • Ilaria Tarantino,
  • Maria Chiara Petrone,
  • Edoardo Forti and ,
  • Stefano Francesco Crinò,
  • Alessandro Fugazza,
  • Roberto Di Mitri,
  • Cecilia Binda,
  • Davide Trama and
  • Carlo Fabbri
  • + 14 authors+ 9 authors

Background: Postoperative fluid collections (POFCs) after abdominal surgeries, particularly pancreatic surgeries, are associated with high morbidity and mortality rates and were historically managed with surgical re-exploration and drainage. In parti...

(This article belongs to the Special Issue Endoscopic Ultrasound (EUS) in Gastrointestinal Diseases)
  • Article
  • Open Access
1 Citations
1,248 Views
20 Pages

Bayesian Integration of Bronchoalveolar Lavage miRNAs and KL-6 in Progressive Pulmonary Fibrosis Diagnosis

  • Piera Soccio,
  • Valerio Longo,
  • Corrado Mencar,
  • Pasquale Tondo and ,
  • Fabiola Murgolo,
  • Giulia Scioscia and
  • Donato Lacedonia
  • + 2 authors+ 0 author

Background/Objectives: Progressive pulmonary fibrosis (PPF) represents one of the most severe and complex challenges in respiratory medicine, characterized by a rapid decline in lung function and often poor prognosis, making it a priority in research...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
1 Citations
2,287 Views
11 Pages

Objectives: The aim of this research was to evaluate the diagnostic performance of Spectralis optical coherence tomography (OCT) parameters for ocular hypertensive (OH) and glaucoma suspect (GS) eyes in an Asian population from Taiwan. Methods: This...

(This article belongs to the Special Issue Diagnosis and Management of Ophthalmic Disorders)
  • Article
  • Open Access
1 Citations
1,277 Views
20 Pages

Deep Reinforcement Learning for CT-Based Non-Invasive Prediction of SOX9 Expression in Hepatocellular Carcinoma

  • Minghui Liu,
  • Yi Wei,
  • Tianshu Xie,
  • Meiyi Yang and ,
  • Xuan Cheng,
  • Lifeng Xu,
  • Qian Li,
  • Feng Che,
  • Qing Xu and
  • Ming Liu
  • + 6 authors+ 1 author

Background: The transcription factor SOX9 plays a critical role in various diseases, including hepatocellular carcinoma (HCC), and has been implicated in resistance to sorafenib treatment. Accurate assessment of SOX9 expression is important for guidi...

(This article belongs to the Special Issue 3rd Edition: AI/ML-Based Medical Image Processing and Analysis)
  • Article
  • Open Access
8 Citations
2,436 Views
14 Pages

Object Detection in Laparoscopic Surgery: A Comparative Study of Deep Learning Models on a Custom Endometriosis Dataset

  • Andrey Bondarenko,
  • Vilen Jumutc,
  • Antoine Netter,
  • Fanny Duchateau and ,
  • Henrique Mendonca Abrão,
  • Saman Noorzadeh,
  • Giuseppe Giacomello,
  • Filippo Ferrari,
  • Nicolas Bourdel and
  • Dmitrijs Bļizņuks
  • + 6 authors+ 1 author

Background: Laparoscopic surgery for endometriosis presents unique challenges due to the complexity of and variability in lesion appearances within the abdominal cavity. This study investigates the application of deep learning models for object detec...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Article
  • Open Access
1 Citations
1,489 Views
16 Pages

Three Neglected STARD Criteria Reduce the Uncertainty of the Liver Fibrosis Biomarker FibroTest-T2D in Metabolic Dysfunction-Associated Steatotic Liver Disease (MASLD)

  • Thierry Poynard,
  • Olivier Deckmyn,
  • Raluca Pais,
  • Judith Aron-Wisnewsky and ,
  • Valentina Peta,
  • Pierre Bedossa,
  • Frederic Charlotte,
  • Maharajah Ponnaiah,
  • Jean-Michel Siksik and
  • Dominique Valla
  • + 8 authors+ 3 authors

Background/Objectives: Bariatric surgery (BS), drugs approved for type-2-diabetes (T2D), obesity, and liver fibrosis (resmetirom) announce the widespread use of fibrosis tests in patients with metabolic liver disease (MASLD). An unmet need is to redu...

(This article belongs to the Section Clinical Diagnosis and Prognosis)
  • Article
  • Open Access
2 Citations
1,685 Views
16 Pages

A Cone-Beam Computed Tomography-Based Assessment of Safe Zones for Orthodontic Mini-Implant Placement in the Lateral Maxilla: A Retrospective Morphometric Study

  • Iva Jakovljevic,
  • Pavle Milanovic,
  • Milica Vasiljevic,
  • Jovana Milanovic and ,
  • Momir Z. Stevanovic,
  • Nemanja Jovicic,
  • Milos Stepovic,
  • Vladimir Ristic,
  • Dragica Selakovic and
  • Aleksandra Arnaut
  • + 6 authors+ 1 author

Background/Objectives: Orthodontic temporary anchorage devices (TADs) in the lateral maxillary region are useful tools for successful orthodontic treatment. Radiological anatomical knowledge is crucial for the successful placement of TADs. The use of...

(This article belongs to the Special Issue Diagnostic Approach and Innovations in the Different Dentistry Fields)
  • Article
  • Open Access
7 Citations
2,203 Views
12 Pages

Diagnostic Performance of Magnetic Resonance Sequences in Staging Lymph Node Involvement and Extranodal Extension in Head and Neck Squamous Cell Carcinoma

  • Giovanni Lorusso,
  • Nicola Maggialetti,
  • Francesca Laugello,
  • Annalisa Garofalo and ,
  • Ilaria Villanova,
  • Sara Greco,
  • Chiara Morelli,
  • Pasquale Pignataro,
  • Nicola Maria Lucarelli and
  • Amato Antonio Stabile Ianora
  • + 5 authors+ 0 author

Objectives: This study aimed to evaluate the diagnostic performance of various MRI sequences in detecting nodal metastasis (N+) and extranodal extension (ENE+) in patients with head and neck squamous cell carcinoma (HNSCC). Methods: A retrospective a...

(This article belongs to the Special Issue Advances in the Diagnosis and Management of Head and Neck Disease)
  • Article
  • Open Access
25 Citations
4,169 Views
25 Pages

Early Detection of Fetal Health Conditions Using Machine Learning for Classifying Imbalanced Cardiotocographic Data

  • Irem Nazli,
  • Ertugrul Korbeko,
  • Seyma Dogru,
  • Emin Kugu and
  • Ozgur Koray Sahingoz

Background: Cardiotocography (CTG) is widely used in obstetrics to monitor fetal heart rate and uterine contractions. It helps detect early signs of fetal distress. However, manual interpretation of CTG can be time-consuming and may vary between clin...

(This article belongs to the Special Issue AI-Driven Diagnostics: Transforming Healthcare from Data to Clinical Decisions)

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Diagnostics - ISSN 2075-4418