Advances in Fetal Imaging

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 1498

Special Issue Editor


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Guest Editor
1. Director of Gertner Institute for Epidemiology and Health Policy Research, Director of Arrow Program for Medical Research Education, Sheba Medical Center, Tel-Hashomer, Tel Aviv, Israel
2. Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel
Interests: fetal imaging; fetal MRI; fetal medicine

Special Issue Information

Dear Colleagues,

The field of fetal medicine has developed dramatically in recent years due to advances in the ability to treat a fetus during the prenatal period, as well as due to significant improvements in genetic and imaging diagnostic capabilities.

Today we are able to discuss not only the anatomical integrity of the various body systems of a fetus, but also their functions.

Beyond this, the improvement in imaging capabilities allows for the understanding of other important components of pregnancy, such as the uterus and placenta, unique fetal conditions, such as intrauterine growth retardation, and unique types of multiple pregnancies.

Beyond the technological improvements that have taken place in the field of ultrasonography, additional imaging tools such as MRI and CT were added and have opened a new world of opportunities.

The combination of advances in imaging capabilities with dramatic advances in genetic diagnosis has changed the field of fetal medicine.

In this Special Issue, we will focus on progress and innovation in fetal imaging.

Prof. Dr. Eldad Katorza
Guest Editor

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Published Papers (1 paper)

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Research

10 pages, 1450 KiB  
Article
Assessing the Agreement Between Diffusion Tension Imaging (DTI) and T2-Weighted MRI Sequence for Biometry of the Fetal Corpus Callosum
by Liel N. Cohn, Shai Bookstein, Tamar Laytman Klein, Nadia Mordenfeld Kozlovsky, Tomer Ziv-Baran, Arnaldo Mayer and Eldad Katorza
Diagnostics 2024, 14(23), 2700; https://doi.org/10.3390/diagnostics14232700 - 29 Nov 2024
Viewed by 786
Abstract
Background/Objectives: Little is known about the advantages of Diffusion Tensor Imaging (DTI) when evaluating the fetal corpus callosum (CC), a sensitive indicator for normal brain development. This study evaluates the contribution of DTI compared to T2-weighted imaging to assess fetal CC biometry. Methods: [...] Read more.
Background/Objectives: Little is known about the advantages of Diffusion Tensor Imaging (DTI) when evaluating the fetal corpus callosum (CC), a sensitive indicator for normal brain development. This study evaluates the contribution of DTI compared to T2-weighted imaging to assess fetal CC biometry. Methods: Data from the fetal MRI exams of singleton pregnancies between July 2017 and 2019 were retrospectively analyzed. Mid-sagittal sections were used to measure the CC biometry, and inter- and intra-observer agreements were assessed using the interclass correlation coefficient (ICC), targeting an ICC above 0.85. Results: The results from 100 patients (mean gestational age, 32.24 weeks) indicated excellent inter-observer reliability for DTI (ICC = 0.904, 95% CI = 0.815–0.952) and moderate agreement for T2-weighted imaging (ICC = 0.719, 95% CI = 0.556–0.842). Intra-observer assessments showed excellent reliability for both DTI and T2-weighted imaging (ICC = 0.967, 95% CI = 0.933–0.984 and ICC = 0.942, 95% CI = 0.884–0.971, respectively). However, a comparison between DTI and T2-weighted images for CC biometry showed poor agreement (ICC = 0.290, 95% CI = 0.071–0.476). Conclusions: In conclusion, the study highlights a lack of agreement between DTI and T2-weighted imaging in fetal CC biometry, suggesting the need for further research to understand this discrepancy and the role of DTI in fetal health. Full article
(This article belongs to the Special Issue Advances in Fetal Imaging)
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