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Diagnostics
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Echocardiography Applications in Cardiovascular Diseases
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Echocardiography Applications in Cardiovascular Diseases

A special issue of Diagnostics (ISSN 2075-4418). This special issue belongs to the section "Medical Imaging and Theranostics".

Deadline for manuscript submissions: 30 November 2025 | Viewed by 4636

Special Issue Editor

Dr. Corina Maria Vasile

E-Mail Website
Guest Editor
Department of Pediatric and Adult Congenital Cardiology, University Hospital of Bordeaux, 33600 Bordeaux, France
Interests: echocardiography; pediatric cardiology; congenital heart disease; congenital cardiopathy in adults; artificial intelligence; automatic measurements
Special Issues, Collections and Topics in MDPI journals

Special Issue Information

Dear Colleagues,

Echocardiography, a non-invasive and widely used imaging technique, has transformed cardiovascular diagnostics and monitoring. As advancements in technology and imaging modalities continue to accelerate, this Special Issue aims to explore the evolving developments in echocardiography and its potential to revolutionize precision cardiovascular diagnostics. Through cutting-edge research and innovative applications, this Special Issue will shed light on the latest trends, challenges, and opportunities in echocardiography, aiming to improve patient care and outcomes.

Topics of Interest:

  • Advanced Echocardiographic Imaging Modalities: A major focus of this section will be on the latest developments in advanced echocardiographic imaging modalities.
  • Artificial Intelligence in Echocardiography: This section will cover research on how integrating artificial intelligence (AI) and machine learning (ML) algorithms can enhance echocardiographic image interpretation and analysis.
  • Echocardiography in Cardiovascular Disease Management: This section will encompass research on the role of echocardiography in cardiovascular disease management, including coronary artery disease, heart failure, valvular heart diseases, and congenital heart anomalies.
  • Echocardiography in Structural Heart Interventions: Structural heart interventions have transformed cardiovascular care, and echocardiography is pivotal in guiding these procedures. This section will delve into the application of echocardiography in procedures such as transcatheter valve interventions, left atrial appendage closures, and patent foramen ovale closures.
  • Striving for Greater Precision via Personalized Echocardiography: As the era of precision medicine unfolds, personalized echocardiography holds promise in tailoring cardiovascular diagnostics and treatment that will cater to individual patient characteristics and needs.
  • Echocardiography and Telemedicine: Telemedicine and remote monitoring have surged, especially in response to global healthcare challenges. This section will explore the integration of echocardiography in telemedicine platforms, its impact on patient accessibility to cardiovascular care, and potential difficulties in remote image acquisition and interpretation.

For this Special Issue, we invite researchers, clinicians, and technology developers to highlight the latest research and innovations in echocardiography with the aim that it will contribute to improved patient care, better disease management, and a deeper understanding of cardiovascular pathophysiology.

Dr. Corina Maria Vasile
Guest Editor

Manuscript Submission Information

Manuscripts should be submitted online at www.mdpi.com by registering and logging in to this website. Once you are registered, click here to go to the submission form. Manuscripts can be submitted until the deadline. All submissions that pass pre-check are peer-reviewed. Accepted papers will be published continuously in the journal (as soon as accepted) and will be listed together on the special issue website. Research articles, review articles as well as short communications are invited. For planned papers, a title and short abstract (about 100 words) can be sent to the Editorial Office for announcement on this website.

Submitted manuscripts should not have been published previously, nor be under consideration for publication elsewhere (except conference proceedings papers). All manuscripts are thoroughly refereed through a single-blind peer-review process. A guide for authors and other relevant information for submission of manuscripts is available on the Instructions for Authors page. Diagnostics is an international peer-reviewed open access semimonthly journal published by MDPI.

Please visit the Instructions for Authors page before submitting a manuscript. The Article Processing Charge (APC) for publication in this open access journal is 2600 CHF (Swiss Francs). Submitted papers should be well formatted and use good English. Authors may use MDPI's English editing service prior to publication or during author revisions.

Keywords

  • echocardiography
  • congenital heart disease
  • imaging techniques
  • artificial intelligence
  • automatization

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Published Papers (4 papers)

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Research

12 pages, 1849 KB  
Article
Significance of the Monitoring Right Ventricular Echocardiographic Parameters in Patients with Hypertrophic Cardiomyopathy Undergoing Alcohol Septal Ablation—A Single-Center Experience
by Tibor Poruban, Ingrid Schusterova, Dominik Pella, Jan Fedacko, Karolina Angela Sieradzka Uchnar, Barbora Sepesiova and Silvia Gurbalova
Diagnostics 2025, 15(19), 2509; https://doi.org/10.3390/diagnostics15192509 - 2 Oct 2025
Viewed by 519
Abstract
Background/Objectives: This study aimed to investigate the association between right ventricular (RV) structure and function and established markers of alcohol septal ablation (ASA) efficacy in patients with hypertrophic cardiomyopathy (HCM). We hypothesized that RV characteristics may serve as predictors of left ventricular outflow [...] Read more.
Background/Objectives: This study aimed to investigate the association between right ventricular (RV) structure and function and established markers of alcohol septal ablation (ASA) efficacy in patients with hypertrophic cardiomyopathy (HCM). We hypothesized that RV characteristics may serve as predictors of left ventricular outflow tract gradient (LVOTG) in the early period following ASA. Methods: A retrospective analysis was performed in 50 HCM patients who underwent ASA. Correlations between echocardiographic RV parameters and standard indicators of ASA success were assessed at 3 months, 1 year, 3 years, and 5 years post-procedure. Results: Echocardiographic measurements of RV wall thickness (RVWT) at 3 months and 1 year after ASA showed significant correlations with maximum LVOTG (p < 0.001), NYHA functional class, and left ventricular end-diastolic dimension (LVD) (both p < 0.01). At 3 and 5 years, these correlations were no longer statistically significant (p = ns). No associations were observed for other parameters. Conclusions: Echocardiographic assessment of RVWT may serve as an early predictor of subsequent LVOTG development as soon as 3 months after ASA. RVWT could therefore provide an estimate of long-term treatment effects. Further studies are needed to confirm these findings. Full article
(This article belongs to the Special Issue Echocardiography Applications in Cardiovascular Diseases)
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13 pages, 1673 KB  
Article
Relationship Between Right Ventricular Function and Body Composition in Adolescents and Young Adults
by Karolina Angela Sieradzka Uchnar, Stefan Toth, Ingrid Schusterova, Dominik Pella, Silvia Gurbalova and Tibor Poruban
Diagnostics 2025, 15(19), 2487; https://doi.org/10.3390/diagnostics15192487 - 29 Sep 2025
Viewed by 466
Abstract
Objective: This study sought to examine the relationships between right ventricular (RV) parameters and function, and body composition in adolescents and young adult individuals with overweight and obesity. We hypothesized that abnormal body composition is linked to RV dysfunction and subclinical changes in [...] Read more.
Objective: This study sought to examine the relationships between right ventricular (RV) parameters and function, and body composition in adolescents and young adult individuals with overweight and obesity. We hypothesized that abnormal body composition is linked to RV dysfunction and subclinical changes in the ventricle. Methods: The study prospectively included 80 young adult individuals, with 55 being overweight or obese and 25 having a normal body weight. We examined differences in RV echocardiographic parameters between these groups and their relationship with body composition parameters. Results: Adolescents and young adults with overweight or obesity had greater RV pressure load, and larger RV diameter. Significant differences in RV size and strain were noted between groups. Across the cohort, lean body mass positively correlated with RV strain, while fat mass and total serum protein negatively correlated with RV strain (both p < 0.01 or lower). Conclusions: This study found that RV function and body composition are often linked and improving body composition could prevent RV dysfunction, while addressing wasting might enhance RV function. Overweight or obese young adults show decreased RV strain in the absolute value compared to those with normal body weight. Full article
(This article belongs to the Special Issue Echocardiography Applications in Cardiovascular Diseases)
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11 pages, 2923 KB  
Article
First-Trimester Morphological Evaluation of Fetuses and Medical Law Implications
by Răzvan Grigoraș Căpitănescu, Marius Cristian Marinaș, Larisa Pătru, Dragoș George Popa, Elena Cristina Andrei, Aura Iuliana Popa, Gabriel Florin Răzvan Mogoș, Nicolae Dragoș Mărgăritescu and Ciprian Laurențiu Pătru
Diagnostics 2025, 15(10), 1277; https://doi.org/10.3390/diagnostics15101277 - 18 May 2025
Viewed by 1072
Abstract
Background/Objectives: Over the years, the potential of the first-trimester (FT) ultrasound in the detection of fetal structural defects has increased. The main objectives of the first-trimester fetal screening evaluation are the detection of major structural anomalies and the diagnosis of additional sonographic markers [...] Read more.
Background/Objectives: Over the years, the potential of the first-trimester (FT) ultrasound in the detection of fetal structural defects has increased. The main objectives of the first-trimester fetal screening evaluation are the detection of major structural anomalies and the diagnosis of additional sonographic markers for chromosomal disorders. When a fetal anomaly is diagnosed, patients have the right to be informed about the risks, necessary interventions, or alternatives. Depending on the severity of the anomalies and the pregnancy period, the legality of the pregnancy termination was evaluated. The aim of this study was to assess the impact of the first-trimester morphological screening of the fetus using an ultrasound protocol according to the latest international protocols (the ISUOG protocol). Methods: Between 1 January 2024 and 31 December 2024, 854 pregnancies with gestational ages between 11 weeks and 13 weeks + 6 days were morphologically evaluated during the nuchal scan in the Obstetrics and Gynecology Department of the Emergency County Hospital from Craiova. Both transabdominal and transvaginal ultrasound in 2D and in a color Doppler mode were used in the scanning technique. The ultrasound findings were correlated with the genetic testing results and pregnancy outcome. The medical law implications were related to the cases where the ultrasound was performed at about 13 weeks of gestation, and the screening genetic results showed an increased pregnancy risk, which arose during the FT. In these cases, we performed amniocentesis at about 16–17 weeks of gestation, and especially, the Non-Invasive Prenatal Testing (NIPT)-positive cases were confirmed by karyotyping. Still, at this gestational age of diagnosis, the Romanian law would not allow abortions. Results: By using this extended FT ultrasound protocol, we detected 58 cases with fetal structural anomalies. Eighteen cases were also associated with genetic syndromes after performing chorionic villous sampling (CVS). Three cases detected with minor structural anomalies (two cases with club foot and one case with a cleft upper lip) were lost to follow-up. Conclusions: Fetal morphological ultrasound evaluation is feasible in the late first trimester. By using an extended ultrasound protocol, we can detect most of the fetal structural anomalies and contribute to better medical counseling and improve pregnancy outcomes. Full article
(This article belongs to the Special Issue Echocardiography Applications in Cardiovascular Diseases)
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11 pages, 9995 KB  
Article
Ultrasound Screening in the First and Second Trimester of Pregnancy for the Detection of Fetal Cardiac Anomalies in a Low-Risk Population
by Aura Iuliana Popa, Nicolae Cernea, Marius Cristian Marinaș, Maria Cristina Comănescu, Ovidiu Costinel Sîrbu, Dragoș George Popa, Larisa Pătru, Vlad Pădureanu and Ciprian Laurențiu Pătru
Diagnostics 2025, 15(6), 769; https://doi.org/10.3390/diagnostics15060769 - 19 Mar 2025
Viewed by 2190
Abstract
Background/Objectives: Congenital heart disease (CHD) is the most common birth defect, an important cause of morbidity and mortality, with a reported prevalence of 5–12 per 1000 live births. The aim of our study was to identify the role of fetal morphological ultrasound examination [...] Read more.
Background/Objectives: Congenital heart disease (CHD) is the most common birth defect, an important cause of morbidity and mortality, with a reported prevalence of 5–12 per 1000 live births. The aim of our study was to identify the role of fetal morphological ultrasound examination in the first and second trimester of pregnancy in the detection of fetal congenital cardiac anomalies in a low-risk population. Methods: We performed a retrospective study in a tertiary fetal medicine center in Emergency Hospital Craiova, Romania. The longitudinal analysis combined first- and second-trimester screening using improved ultrasound protocols. Our study evaluated 8944 pregnant women with singleton pregnancies in a 6-year period between January 2018 and December 2023. All ultrasound examinations were performed using a standard extended protocol according to the main guidelines’ recommendations for the detection of fetal anomalies. Results: In the first trimester of pregnancy, 37 cases with cardiac anomalies were diagnosed. Thirteen of these cases were associated with genetic anomalies (Down syndrome—eight cases, Edwards syndrome—four cases, Turner syndrome—one case). Some of these pregnancies were associated with at least one of the minor ultrasound markers (inverted ductus venosus, abnormal flow in the tricuspid valve, presence of choroid plexus cysts, absent/hypoplastic nasal bone). In the second trimester of pregnancy, 17 cases of cardiac anomalies were diagnosed. From these cases, one was associated with genetic anomalies (DiGeorge Syndrome), and one case developed hydrops and delivered prematurely in the early third trimester. Conclusions: Ultrasound screening for the detection of congenital heart disease is feasible early in pregnancy, but some anomalies would be obvious later in pregnancy. An early diagnosis using an extended ultrasound protocol, genetic testing, and a multidisciplinary evaluation would improve the prognosis and the overall survival rate by delivering in a tertiary center that allows for rapid cardiac surgery in dedicated cases. Full article
(This article belongs to the Special Issue Echocardiography Applications in Cardiovascular Diseases)
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