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Diagnostics, Volume 14, Issue 15

2024 August-1 - 120 articles

Cover Story: Digital PCR (dPCR) offers unmatched precision and sensitivity in nucleic acid detection and quantification, making it a transformative tool in molecular biology. The following review explores its evolution from traditional PCR, emphasizing its role in infectious disease diagnostics, environmental surveillance, and sepsis management. dPCR enables accurate absolute quantification through advanced partitioning, showcasing superior sensitivity for early pathogen detection. In the review, commercial platforms are compared and applications in water microbiology, including wastewater surveillance, are discussed. Despite challenges such as high costs and standardization, dPCR holds promise for revolutionizing pathogen identification across diverse fields. View this paper
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Articles (120)

  • Article
  • Open Access
8 Citations
2,340 Views
15 Pages

Enhancing Veress Needle Entry with Proximal Vibroacoustic Sensing for Automatic Identification of Peritoneum Puncture

  • Moritz Spiller,
  • Nazila Esmaeili,
  • Thomas Sühn,
  • Axel Boese,
  • Salmai Turial,
  • Andrew A. Gumbs,
  • Roland Croner,
  • Michael Friebe and
  • Alfredo Illanes

Laparoscopic access, a critical yet challenging step in surgical procedures, often leads to complications. Existing systems, such as improved Veress needles and optical trocars, offer limited safety benefits but come with elevated costs. In this stud...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Review
  • Open Access
13 Citations
5,566 Views
18 Pages

Anatomical Factors of the Anterior and Posterior Maxilla Affecting Immediate Implant Placement Based on Cone Beam Computed Tomography Analysis: A Narrative Review

  • Milica Vasiljevic,
  • Dragica Selakovic,
  • Gvozden Rosic,
  • Momir Stevanovic,
  • Jovana Milanovic,
  • Aleksandra Arnaut and
  • Pavle Milanovic

Background: The aim of this narrative review was to provide insights into the influence of the morphological characteristics of the anatomical structures of the upper jaw based on cone beam computed tomography (CBCT) analysis on the immediate implant...

(This article belongs to the Special Issue Advances in the Diagnosis of Oral and Maxillofacial Disease)
  • Article
  • Open Access
5 Citations
3,575 Views
17 Pages

A Cross-Sectional Validation of Horos and CoreSlicer Software Programs for Body Composition Analysis in Abdominal Computed Tomography Scans in Colorectal Cancer Patients

  • Andrés Jiménez-Sánchez,
  • María Elisa Soriano-Redondo,
  • José Luis Pereira-Cunill,
  • Antonio Jesús Martínez-Ortega,
  • José Ramón Rodríguez-Mowbray,
  • Irene María Ramallo-Solís and
  • Pedro Pablo García-Luna

Background: Body composition assessment using computed tomography (CT) scans may be hampered by software costs. To facilitate its implementation in resource-limited settings, two open-source segmentation programs (Horos and CoreSlicer) were transvers...

(This article belongs to the Special Issue Advances in Diagnostic and Interventional Radiology)
  • Article
  • Open Access
3 Citations
2,491 Views
15 Pages

Comparative Efficacy and Safety of Self-Expandable vs. Balloon-Expandable Stent Grafts in Visceral Artery Aneurysm Management

  • Reza Talaie,
  • Pooya Torkian,
  • Anthony Spano,
  • Alireza Mahjoubnia,
  • Siobhan M. Flanagan,
  • Michael Rosenberg,
  • Jian Lin,
  • Jafar Golzarian and
  • Preshant Shrestha

Purpose: This study assesses the efficacy and safety of self-expandable (SE) versus balloon-expandable (BE) stent grafts for managing visceral artery aneurysms (VAAs), focusing on procedural success and complication rates. Materials and Methods: We c...

(This article belongs to the Special Issue Diagnosis and Management of Cardiovascular Disorders)
  • Systematic Review
  • Open Access
1 Citations
4,166 Views
16 Pages

Despite the increased use of diagnostic imaging in Africa, the completion of the Radiology Request Form (RRF) remains suboptimal, often relying on paper-based communication. To examine the practices surrounding RRF completion in the African continent...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
3 Citations
2,803 Views
12 Pages

Compressed SENSitivity Encoding (SENSE): Qualitative and Quantitative Analysis

  • Eliseo Picchi,
  • Silvia Minosse,
  • Noemi Pucci,
  • Francesca Di Pietro,
  • Maria Lina Serio,
  • Valentina Ferrazzoli,
  • Valerio Da Ros,
  • Raffaella Giocondo,
  • Francesco Garaci and
  • Francesca Di Giuliano

Background. This study aimed to qualitatively and quantitatively evaluate T1-TSE, T2-TSE and 3D FLAIR sequences obtained with and without Compressed-SENSE technique by assessing the contrast (C), the contrast-to-noise ratio (CNR) and the signal-to-no...

(This article belongs to the Special Issue Clinical Advances and Applications in Neuroradiology)
  • Article
  • Open Access
3 Citations
3,074 Views
10 Pages

An Immunohistochemical Study of MAGE Proteins in Hepatocellular Carcinoma

  • Stylianos Tologkos,
  • Vasiliki Papadatou,
  • Achilleas G. Mitrakas,
  • Olga Pagonopoulou,
  • Grigorios Tripsianis,
  • Triantafyllos Alexiadis,
  • Christina-Angelika Alexiadi,
  • Antonios-Periklis Panagiotopoulos,
  • Christina Nikolaidou and
  • Maria Lambropoulou

Hepatocellular carcinoma (HCC) is one the most common primary malignancies with high mortality and morbidity. The melanoma-associated antigen (MAGE) gene family includes several genes that are highly expressed in numerous human cancers, making many o...

(This article belongs to the Special Issue Pathology of Hepatobiliary Diseases)
  • Article
  • Open Access
11 Citations
3,583 Views
26 Pages

Hybrid Feature Mammogram Analysis: Detecting and Localizing Microcalcifications Combining Gabor, Prewitt, GLCM Features, and Top Hat Filtering Enhanced with CNN Architecture

  • Miguel Alejandro Hernández-Vázquez,
  • Yazmín Mariela Hernández-Rodríguez,
  • Fausto David Cortes-Rojas,
  • Rafael Bayareh-Mancilla and
  • Oscar Eduardo Cigarroa-Mayorga

Breast cancer is a prevalent malignancy characterized by the uncontrolled growth of glandular epithelial cells, which can metastasize through the blood and lymphatic systems. Microcalcifications, small calcium deposits within breast tissue, are criti...

(This article belongs to the Section Machine Learning and Artificial Intelligence in Diagnostics)
  • Case Report
  • Open Access
4 Citations
2,493 Views
6 Pages

Parathyroid Adenoma Detected in 68Ga-PSMA PET/CT but Not in the Dedicated Imaging Modalities

  • Maja Cieślewicz,
  • Natalia Andryszak,
  • Kacper Pełka,
  • Ewelina Szczepanek-Parulska,
  • Marek Ruchała,
  • Jolanta Kunikowska and
  • Rafał Czepczyński

Background: Primary hyperparathyroidism is a common endocrine disorder characterised by excessive parathormone secretion that results in hypercalcemia, primarily caused by parathyroid adenoma. Accurate localisation of hyperfunctioning tissue is essen...

(This article belongs to the Special Issue Research Update on Nuclear Medicine)
  • Article
  • Open Access
5 Citations
3,548 Views
13 Pages

We investigated whether radiomics of computed tomography (CT) image data enables the differentiation of bone metastases not visible on CT from unaffected bone, using pathologically confirmed bone metastasis as the reference standard, in patients with...

(This article belongs to the Special Issue Application of Artificial Intelligence in Gastrointestinal Disease)
  • Article
  • Open Access
2 Citations
1,999 Views
12 Pages

Enhancing Retina Images by Lowpass Filtering Using Binomial Filter

  • Mofleh Hannuf AlRowaily,
  • Hamzah Arof,
  • Imanurfatiehah Ibrahim,
  • Haniza Yazid and
  • Wan Amirul Mahyiddin

This study presents a method to enhance the contrast and luminosity of fundus images with boundary reflection. In this work, 100 retina images taken from online databases are utilized to test the performance of the proposed method. First, the red, gr...

(This article belongs to the Special Issue Advances in Medical Image Processing, Segmentation and Classification)
  • Article
  • Open Access
11 Citations
6,171 Views
18 Pages

Evaluation of the Alveolar Crest and Cemento-Enamel Junction in Periodontitis Using Object Detection on Periapical Radiographs

  • Tai-Jung Lin,
  • Yi-Cheng Mao,
  • Yuan-Jin Lin,
  • Chin-Hao Liang,
  • Yi-Qing He,
  • Yun-Chen Hsu,
  • Shih-Lun Chen,
  • Tsung-Yi Chen,
  • Chiung-An Chen and
  • Patricia Angela R. Abu
  • + 1 author

The severity of periodontitis can be analyzed by calculating the loss of alveolar crest (ALC) level and the level of bone loss between the tooth’s bone and the cemento-enamel junction (CEJ). However, dentists need to manually mark symptoms on p...

(This article belongs to the Special Issue Artificial Intelligence in the Diagnostics of Dental Disease)
  • Article
  • Open Access
3 Citations
2,439 Views
11 Pages

This 10-year retrospective cohort study at a single-center clinic in Germany aimed to analyze the outcomes of endometrial cancer patients and explore the impact of lymphovascular invasion (LV) on patient outcomes and disease-free survival (DFS). Iden...

(This article belongs to the Special Issue Advances in the Diagnosis and Management of Gynecological Oncology)
  • Article
  • Open Access
7 Citations
2,182 Views
12 Pages

Prognostic Utility of dNLR, ALRI, APRI, and SII in COVID-19 Patients with Diabetes: A Cross-Sectional Study

  • Alexandra Ioana Danila,
  • Flavius Cioca,
  • Sai Teja Gadde,
  • Sai Praveen Daruvuri,
  • Romulus Timar and
  • Elena Hogea

The coronavirus disease 2019 (COVID-19) pandemic has necessitated the identification of biomarkers that can predict disease severity, particularly in vulnerable populations such as individuals with diabetes. This study aims to evaluate the predictive...

(This article belongs to the Special Issue Advances in the Diagnosis of Infectious Diseases and Microorganisms)
  • Article
  • Open Access
3 Citations
2,875 Views
17 Pages

Background: Knowledge of the anatomy of pulmonary arteries is essential in many invasive procedures concerning pulmonary circulation. In the diagnosis and treatment of chronic thromboembolic pulmonary hypertension (CTEPH), two-dimensional (2D) pulmon...

(This article belongs to the Special Issue Advances in Human Anatomy)
  • Article
  • Open Access
1 Citations
1,898 Views
12 Pages

Cone beam computed tomography (CBCT) can provide precise information about complex anatomical structures as it is characterised by rapid volumetric image acquisition with high resolution. The aim of this study was to provide measurements for 20 ancie...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
1,844 Views
11 Pages

Role of Cine-Magnetic Resonance Imaging in the Assessment of Mediastinal Masses with Uncertain/Equivocal Findings from Pre-Operative Computed Tomography Scanning

  • Umberto Cariboni,
  • Lorenzo Monti,
  • Emanuele Voulaz,
  • Efrem Civilini,
  • Enrico Citterio,
  • Costanza Lisi and
  • Giuseppe Marulli

Background: Malignant neoplasms originating from or involving the mediastinum represent a diagnostic and therapeutic challenge when they are in contact with nearby cardiovascular structures. We aimed to test the diagnostic accuracy of cine-magnetic r...

(This article belongs to the Special Issue Medical Radiology in Italy: Current Progress)
  • Article
  • Open Access
1 Citations
1,650 Views
9 Pages

Quantitative Edge Analysis Can Differentiate Pancreatic Carcinoma from Normal Pancreatic Parenchyma

  • Maria Chiara Ambrosetti,
  • Alberto Ambrosetti,
  • Matilde Bariani,
  • Giuseppe Malleo,
  • Giancarlo Mansueto and
  • Giulia A. Zamboni

This study aimed to introduce specific image feature analysis, focusing on pancreatic margins, and to provide a quantitative measure of edge irregularity, evidencing correlations with the presence/absence of pancreatic adenocarcinoma. We selected 50...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
5 Citations
3,466 Views
12 Pages

Developmental delays (DD) and congenital anomalies (CA) are prevalent yet often remain undiagnosed despite comprehensive genetic testing. This study aims to investigate the diagnostic yield of trio whole-genome sequencing (WGS) in children presenting...

(This article belongs to the Special Issue Clinical Prognostic and Predictive Biomarkers, 2nd Edition)
  • Interesting Images
  • Open Access
3 Citations
2,153 Views
7 Pages

A Case of Dedifferentiated Liposarcoma That Contributes to Accompanying Vessels of Various Size

  • Yosuke Yamada,
  • Kai Mizoguchi,
  • Eisuke Shiba,
  • Honami Mishima,
  • Shinya Otsuki,
  • Masahito Hoki,
  • Masahiro Hirata,
  • Akio Sakamoto,
  • Shuichi Matsuda and
  • Hironori Haga
  • + 2 authors

Dedifferentiated liposarcoma (DDLPS) is a non-lipogenic sarcoma, generally arising from well-differentiated liposarcoma (WDLPS), although it can develop de novo. DDLPS tumors rarely trans-differentiate into non-adipose mesenchymal tissues; however, t...

(This article belongs to the Special Issue Clinical Prognostic and Predictive Biomarkers, 2nd Edition)
  • Article
  • Open Access
4 Citations
11,644 Views
11 Pages

Nasal irrigation is crucial following endoscopic sinus surgery (ESS), especially for managing chronic rhinosinusitis (CRS). This study assessed the effectiveness of N-acetylcysteine (NAC) irrigation during the post-ESS period of patients with CRS wit...

(This article belongs to the Special Issue Advances in Diagnosis and Treatment in Otolaryngology)
  • Article
  • Open Access
12 Citations
3,528 Views
14 Pages

Evaluation of Machine Learning Classification Models for False-Positive Reduction in Prostate Cancer Detection Using MRI Data

  • Malte Rippa,
  • Ruben Schulze,
  • Georgia Kenyon,
  • Marian Himstedt,
  • Maciej Kwiatkowski,
  • Rainer Grobholz,
  • Stephen Wyler,
  • Alexander Cornelius,
  • Sebastian Schindera and
  • Felice Burn

In this work, several machine learning (ML) algorithms, both classical ML and modern deep learning, were investigated for their ability to improve the performance of a pipeline for the segmentation and classification of prostate lesions using MRI dat...

(This article belongs to the Topic AI in Medical Imaging and Image Processing)
  • Article
  • Open Access
2 Citations
3,021 Views
17 Pages

Objective: To investigate the relationships of sleep patterns and respiratory disturbance index (RDI) with key physiological parameters (height, body mass index (BMI), bone age (BA), and IGF-1 levels) in children aged 6 to 16 years with self-perceive...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
1 Citations
2,067 Views
10 Pages

Differentiating Well-Differentiated from Poorly-Differentiated HCC: The Potential and the Limitation of Gd-EOB-DTPA in the Presence of Liver Cirrhosis

  • Andrea Goetz,
  • Niklas Verloh,
  • Kirsten Utpatel,
  • Claudia Fellner,
  • Janine Rennert,
  • Ingo Einspieler,
  • Michael Doppler,
  • Lukas Luerken,
  • Leona S. Alizadeh and
  • Michael Haimerl
  • + 2 authors

This study uses magnetic resonance imaging (MRI) to investigate the potential of the hepatospecific contrast agent gadolinium ethoxybenzyl-diethylenetriaminepentaacetic acid (Gd-EOB-DTPA) in distinguishing G1- from G2/G3-differentiated hepatocellular...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
1 Citations
4,364 Views
13 Pages

Purpose: Therapeutic hypothermia (TH) is widely acknowledged as one of the interventions for preventing hypoxic ischemic brain injury in comatose patients following cardiac arrest (CA). Despite its recognized efficacy, recent debates have questioned...

(This article belongs to the Special Issue Diagnosis and Management in Emergency Medicine)
  • Article
  • Open Access
2 Citations
2,272 Views
16 Pages

Nasal Microbiome in Granulomatosis with Polyangiitis Compared to Chronic Rhinosinusitis

  • Eliza Brożek-Mądry,
  • Zofia Burska,
  • Katarzyna Życińska and
  • Janusz Sierdziński

Rhinosinusitis in granulomatosis with polyangiitis (GPA) is categorised as a secondary, diffuse and inflammatory chronic rhinosinusitis (CRS). It is one of the conditions that impacts the nasal microbiota. This study aimed to compare the nasal microb...

(This article belongs to the Special Issue Advances in Diagnosis and Treatment in Otolaryngology)
  • Article
  • Open Access
31 Citations
4,250 Views
18 Pages

Assessing the Efficacy of the Spectrum-Aided Vision Enhancer (SAVE) to Detect Acral Lentiginous Melanoma, Melanoma In Situ, Nodular Melanoma, and Superficial Spreading Melanoma

  • Teng-Li Lin,
  • Chun-Te Lu,
  • Riya Karmakar,
  • Kalpana Nampalley,
  • Arvind Mukundan,
  • Yu-Ping Hsiao,
  • Shang-Chin Hsieh and
  • Hsiang-Chen Wang

Skin cancer is the predominant form of cancer worldwide, including 75% of all cancer cases. This study aims to evaluate the effectiveness of the spectrum-aided visual enhancer (SAVE) in detecting skin cancer. This paper presents the development of a...

(This article belongs to the Special Issue Optical Imaging: Trends, Impact, and Application in Medical and Biomedical Diagnostics)
  • Review
  • Open Access
10 Citations
6,451 Views
25 Pages

Computed Tomography Angiography Identified High-Risk Coronary Plaques: From Diagnosis to Prognosis and Future Management

  • Kyriakos Dimitriadis,
  • Nikolaos Pyrpyris,
  • Panagiotis Theofilis,
  • Emmanouil Mantzouranis,
  • Eirini Beneki,
  • Panagiotis Kostakis,
  • George Koutsopoulos,
  • Konstantinos Aznaouridis,
  • Konstantina Aggeli and
  • Konstantinos Tsioufis

CT angiography has become, in recent years, a main evaluating modality for patients with coronary artery disease (CAD). Recent advancements in the field have allowed us to identity not only the presence of obstructive disease but also the characteris...

(This article belongs to the Special Issue New Trends and Advances in Cardiac Imaging)
  • Systematic Review
  • Open Access
10 Citations
5,359 Views
13 Pages

Audiovestibular Dysfunction in Systemic Lupus Erythematosus Patients: A Systematic Review

  • Jiann-Jy Chen,
  • Chih-Wei Hsu,
  • Yen-Wen Chen,
  • Tien-Yu Chen,
  • Bing-Syuan Zeng and
  • Ping-Tao Tseng

Audiovestibular dysfunction in patients with systemic lupus erythematosus has been underestimated for decades. Systemic lupus erythematosus can affect both the auditory and vestibular systems simultaneously. Several potential pathophysiological mecha...

(This article belongs to the Section Clinical Laboratory Medicine)
  • Review
  • Open Access
54 Citations
9,746 Views
16 Pages

Artificial Intelligence (AI) Applications for Point of Care Ultrasound (POCUS) in Low-Resource Settings: A Scoping Review

  • Seungjun Kim,
  • Chanel Fischetti,
  • Megan Guy,
  • Edmund Hsu,
  • John Fox and
  • Sean D. Young

Advancements in artificial intelligence (AI) for point-of-care ultrasound (POCUS) have ushered in new possibilities for medical diagnostics in low-resource settings. This review explores the current landscape of AI applications in POCUS across these...

(This article belongs to the Section Point-of-Care Diagnostics and Devices)
  • Review
  • Open Access
15 Citations
7,120 Views
18 Pages

Exploring Publicly Accessible Optical Coherence Tomography Datasets: A Comprehensive Overview

  • Anastasiia Rozhyna,
  • Gábor Márk Somfai,
  • Manfredo Atzori,
  • Delia Cabrera DeBuc,
  • Amr Saad,
  • Jay Zoellin and
  • Henning Müller

Artificial intelligence has transformed medical diagnostic capabilities, particularly through medical image analysis. AI algorithms perform well in detecting abnormalities with a strong performance, enabling computer-aided diagnosis by analyzing the...

(This article belongs to the Special Issue Updates on the Diagnosis and Management of Retinal Diseases)
  • Article
  • Open Access
12 Citations
2,231 Views
12 Pages

The Radiogenomic Landscape of Clear Cell Renal Cell Carcinoma: Insights into Lipid Metabolism through Evaluation of ADFP Expression

  • Federico Greco,
  • Andrea Panunzio,
  • Caterina Bernetti,
  • Alessandro Tafuri,
  • Bruno Beomonte Zobel and
  • Carlo Augusto Mallio

This study aims to explore the relationship between radiological imaging and genomic characteristics in clear cell renal cell carcinoma (ccRCC), focusing on the expression of adipose differentiation-related protein (ADFP) detected through computed to...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
1,670 Views
13 Pages

The 2018 WHO edition on the classification of cutaneous melanocytic tumors recognizes eight evolutionary pathways of melanoma and describes tumors of uncertain malignant potential for each. When histology and immunohistochemistry do not support a con...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Review
  • Open Access
13 Citations
5,143 Views
24 Pages

Background. The diagnosis and treatment of head and neck tumors present significant challenges due to their infiltrative nature and diagnostic hindrances such as the blood–brain barrier. The intricate anatomy of the head and neck region also co...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Review
  • Open Access
22 Citations
7,068 Views
10 Pages

Utilizing Next-Generation Sequencing: Advancements in the Diagnosis of Fungal Infections

  • Sheetal Naik,
  • Dharambir Kashyap,
  • Jashan Deep,
  • Saif Darwish,
  • Joseph Cross,
  • Edmond Mansoor,
  • Vivek Kumar Garg and
  • Prasanna Honnavar

Next-generation sequencing (NGS) has emerged as a promising tool for diagnosing fungal infections. It enables the identification of a wide range of fungal species and provides more accurate and rapid results than traditional diagnostic methods. NGS-b...

(This article belongs to the Special Issue Advances in the Diagnosis of Infectious Diseases and Microorganisms)
  • Article
  • Open Access
9 Citations
2,765 Views
11 Pages

Background: Asthma is a chronic inflammatory condition characterized by episodes of acute asthma exacerbations (AAEs), in addition to chronic airway inflammation, which has a huge impact on both the affected patients and their parents. The main objec...

(This article belongs to the Special Issue Diagnostics in the Emergency and Critical Care Medicine)
  • Article
  • Open Access
4 Citations
1,989 Views
12 Pages

Fluoroscopic-Guided vs. Multislice Computed Tomography (CT) Biopsy Mode-Guided Percutaneous Radiologic Gastrostomy (PRG)—Comparison of Interventional Parameters and Billing

  • Michael P. Brönnimann,
  • Jagoda Kulagowska,
  • Bernhard Gebauer,
  • Timo A. Auer,
  • Federico Collettini,
  • Dirk Schnapauff,
  • Christian T. J. Magyar,
  • Alois Komarek,
  • Miltiadis Krokidis and
  • Johannes T. Heverhagen

Background: This study investigated and compared the efficacy, safety, radiation exposure, and financial compensation of two modalities for percutaneous radiologic gastrostomy (PRG): multislice computed tomography biopsy mode (MS-CT BM)-guided and fl...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
3 Citations
2,828 Views
14 Pages

Baseline Normative and Test–Retest Reliability Data for Sideline Concussion Assessment Measures in Youth

  • Jennifer V. Wethe,
  • Jamie Bogle,
  • David W. Dodick,
  • Marci D. Howard,
  • Amanda Rach Gould,
  • Richard J. Butterfield,
  • Matthew R. Buras,
  • Jennifer Adler,
  • Alexandra Talaber and
  • Amaal J. Starling
  • + 1 author

Tools used for the identification, evaluation, and monitoring of concussion have not been sufficiently studied in youth or real-world settings. Normative and reliability data on sideline concussion assessment measures in the youth athlete population...

(This article belongs to the Special Issue The Assessment, Diagnosis, and Management of Sport-Related Concussion in Childhood and Adolescence)
  • Article
  • Open Access
4 Citations
2,074 Views
13 Pages

Osteoarthritis (OA) is a degenerative joint disease characterised by the breakdown of cartilage, causing pain, stiffness, and limited movement. Early diagnosis is crucial for effective management but remains challenging due to non-specific early symp...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
4 Citations
3,072 Views
11 Pages

Incidence and Antenatal Detection of Congenital Heart Malformations—Data from a Tertiary Obstetric Romanian Center

  • Adrian Ciulpan,
  • Adrian Lacatușu,
  • Liviu Laurenţiu Pop,
  • Corina Paul,
  • Diana Lungeanu,
  • Daniela Iacob,
  • Brenda-Cristiana Bernad,
  • Ana Lascu,
  • Edida Maghet and
  • Elena Silvia Bernad
  • + 1 author

Objectives: Congenital heart defects (CHDs) are among the most frequent congenital defects, and they significantly burden the healthcare system due to their high mortality rate and high cost of care for survivors. We aimed to highlight the incidence...

(This article belongs to the Special Issue Editorial Board Members' Collection Series: Advances in Gynecology and Obstetrics)
  • Systematic Review
  • Open Access
18 Citations
4,125 Views
15 Pages

Systematic Review on the Use of 3D-Printed Models for Planning, Training and Simulation in Vascular Surgery

  • Alexandra Catasta,
  • Chiara Martini,
  • Arianna Mersanne,
  • Ruben Foresti,
  • Claudio Bianchini Massoni,
  • Antonio Freyrie and
  • Paolo Perini

The use of 3D-printed models in simulation-based training and planning for vascular surgery is gaining interest. This study aims to provide an overview of the current applications of 3D-printing technologies in vascular surgery. We performed a system...

(This article belongs to the Special Issue Advances in Imaging Diagnosis and Management of Cardiovascular and Pulmonary Diseases)
  • Article
  • Open Access
8 Citations
3,089 Views
12 Pages

Shear-Wave Elastography Gradient Analysis of Newly Diagnosed Breast Tumours: A Critical Analysis

  • Johannes Deeg,
  • Michael Swoboda,
  • Daniel Egle,
  • Verena Wieser,
  • Afschin Soleiman,
  • Valentin Ladenhauf,
  • Malik Galijasevic,
  • Birgit Amort and
  • Leonhard Gruber

Background: A better understanding of the peritumoral stroma changes due to tumour invasion using non-invasive diagnostic methods may improve the differentiation between benign and malignant breast lesions. This study aimed to assess the correlation...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
6 Citations
2,693 Views
15 Pages

LiverColor: An Artificial Intelligence Platform for Liver Graft Assessment

  • Gemma Piella,
  • Nicolau Farré,
  • Daniel Esono,
  • Miguel Ángel Cordobés,
  • Javier Vázquez-Corral,
  • Itxarone Bilbao and
  • Concepción Gómez-Gavara

Hepatic steatosis, characterized by excess fat in the liver, is the main reason for discarding livers intended for transplantation due to its association with increased postoperative complications. The current gold standard for evaluating hepatic ste...

(This article belongs to the Special Issue Artificial Intelligence and Deep Learning in Clinical Classification and Prediction)
  • Article
  • Open Access
8 Citations
4,420 Views
15 Pages

Diagnostic Accuracy of Non-Contrast-Enhanced Time-Resolved MR Angiography to Assess Angioarchitectural Classification Features of Brain Arteriovenous Malformations

  • Grégoire Chauvet,
  • Mourad Cheddad El Aouni,
  • Elsa Magro,
  • Ophélie Sabardu,
  • Douraied Ben Salem,
  • Jean-Christophe Gentric and
  • Julien Ognard

This study aims to assess the diagnostic accuracy of non-contrast-enhanced 4D MR angiography (NCE-4D-MRA) compared to contrast-enhanced 4D MR angiography (CE-4D-MRA) for the detection and angioarchitectural characterisation of brain arteriovenous mal...

(This article belongs to the Special Issue Advances in Cerebrovascular Imaging and Interventions)
  • Article
  • Open Access
4 Citations
2,536 Views
15 Pages

Deep Learning Based Automatic Left Ventricle Segmentation from the Transgastric Short-Axis View on Transesophageal Echocardiography: A Feasibility Study

  • Yuan Tian,
  • Wenting Qin,
  • Zihang Zhao,
  • Chunrong Wang,
  • Yajie Tian,
  • Yuelun Zhang,
  • Kai He,
  • Yuguan Zhang,
  • Le Shen and
  • Chunhua Yu
  • + 1 author

Segmenting the left ventricle from the transgastric short-axis views (TSVs) on transesophageal echocardiography (TEE) is the cornerstone for cardiovascular assessment during perioperative management. Even for seasoned professionals, the procedure rem...

(This article belongs to the Special Issue Deep Learning Techniques for Medical Image Analysis)
  • Interesting Images
  • Open Access
1 Citations
2,080 Views
4 Pages

We present a rare case of focal F-18-2-fluoro-2-deoxyglucose (FDG) uptake in the liver observed during a modified dual-time-point F-18 FDG positron emission tomography (PET)/computed tomography (CT), so-called early delayed scanning, in a 53-year-old...

(This article belongs to the Section Medical Imaging and Theranostics)
  • Article
  • Open Access
2 Citations
3,523 Views
13 Pages

Efficacy of Ultrasound for the Detection of Possible Fatty Liver Disease in Children

  • Sarah B. Lowry,
  • Shelly Joseph,
  • Kevin J. Psoter,
  • Emily Dunn,
  • Sana Mansoor,
  • S. Kathryn Smith,
  • Wikrom Karnsakul,
  • Gihan Naguib,
  • Kenneth Ng and
  • Ann O. Scheimann

Pediatric MASLD (previously referred to as NAFLD) incidence has continued to rise along with the obesity pandemic. Pediatric MASLD increases the risk of liver fibrosis and cirrhosis in adulthood. Early detection and intervention can prevent and reduc...

(This article belongs to the Section Pathology and Molecular Diagnostics)
  • Article
  • Open Access
2 Citations
2,125 Views
10 Pages

Relationship between Volpara Density Grade and Compressed Breast Thickness in Japanese Patients with Breast Cancer

  • Mio Adachi,
  • Toshiyuki Ishiba,
  • Sakiko Maruya,
  • Kumiko Hayashi,
  • Yuichi Kumaki,
  • Goshi Oda and
  • Tomoyuki Aruga

Background: High breast density found using mammographs (MGs) reduces positivity rates and is considered a risk factor for breast cancer. Research on the relationship between Volpara density grade (VDG) and compressed breast thickness (CBT) in the Ja...

(This article belongs to the Special Issue Advances in Breast Radiology)
  • Article
  • Open Access
1 Citations
2,482 Views
13 Pages

Evaluation of Progressive Architectural Distortion in Idiopathic Pulmonary Fibrosis Using Deformable Registration of Sequential CT Images

  • Naofumi Yasuda,
  • Tae Iwasawa,
  • Tomohisa Baba,
  • Toshihiro Misumi,
  • Shihyao Cheng,
  • Shingo Kato,
  • Daisuke Utsunomiya and
  • Takashi Ogura

Background: Monitoring the progression of idiopathic pulmonary fibrosis (IPF) using CT primarily focuses on assessing the extent of fibrotic lesions, without considering the distortion of lung architecture. Objectives: To evaluate three-dimensional a...

(This article belongs to the Special Issue Advances in Imaging Diagnosis and Management of Cardiovascular and Pulmonary Diseases)
  • Article
  • Open Access
2 Citations
1,924 Views
26 Pages

A Multimodal Fuzzy Approach in Evaluating Pediatric Chronic Kidney Disease Using Kidney Biomarkers

  • Cristian Petru Dușa,
  • Valentin Bejan,
  • Marius Pislaru,
  • Iuliana Magdalena Starcea and
  • Ionela Lacramioara Serban

Chronic kidney disease (CKD) is one of the most important causes of chronic pediatric morbidity and mortality and places an important burden on the medical system. Current diagnosis and progression monitoring techniques have numerous sensitivity and...

(This article belongs to the Special Issue Artificial Intelligence in Clinical Decision Support)

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Diagnostics - ISSN 2075-4418