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Life, Volume 15, Issue 12

December 2025 - 158 articles

Cover Story: Extreme environments harbour an unexplored treasure trove of extremophile microorganisms, adapted to harsh conditions. Extremophiles produce unique compounds which exhibit antioxidant, anti-inflammatory, photoprotective, and regenerative properties. The integration of extremophile-derived bioactives into cosmeceuticals and nutricosmetics provides a new means of improving skin health through both topical and systemic approaches. Extremophile-derived ingredients combine biological efficacy with environmental sustainability, positioning them as key assets for next-generation skincare. Future directions include clinical validation, regulatory harmonization, and the development of personalized, microbiome-friendly formulations. View this paper
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Articles (158)

  • Article
  • Open Access
207 Views
22 Pages

17 December 2025

Cyanobacterial blooms pose significant threats to aquatic ecosystems and drinking water safety, primarily through the release of diverse secondary metabolites. This study systematically explored the dynamics of secondary metabolites in Microcystis ae...

  • Systematic Review
  • Open Access
332 Views
25 Pages

17 December 2025

Personalized exercise prescriptions require identifying inter-individual differences in exercise intervention effects. This review examined whether true inter-individual differences exist after accounting for measurement error. PubMed, Web of Science...

  • Article
  • Open Access
259 Views
13 Pages

17 December 2025

Objective: Identifying biomarkers that predict metastatic potential or guide treatment selection is critical for improving breast cancer (BC) management. Previously, we established the Mitotic Network Activity Index (MNAI) as a prognostic marker in B...

  • Article
  • Open Access
318 Views
14 Pages

17 December 2025

Background: The benefit of adjuvant chemotherapy for low-risk, mismatch repair proficient (pMMR) stage IIA colon cancer is uncertain. Surveillance is standard, but some patients relapse. Tegafur-uracil (UFT) is a low-toxicity oral option that may off...

  • Article
  • Open Access
279 Views
18 Pages

17 December 2025

Purpose: This study investigated the effects of dietary bamboo leaf extract (BLE) on milk parameters and intestinal microbiota in lactating Yili mares. Methods: Twenty-four Yili mares of similar age (10 ± 2 years), weight (360.62 ± 15.2...

  • Article
  • Open Access
229 Views
17 Pages

Predictors of 30-Day Mortality in Trauma: A Single-Center Retrospective Exploratory Study

  • Irina-Anca Eremia,
  • Cătălin-Alexandru Anghel,
  • Horia Alexandru Nica,
  • Eduard-Alexandru Eremia,
  • Ionuț-Lucian Antone-Iordache,
  • Adrian-Gabriel Borcan,
  • Daniel Iulian Voiculescu and
  • Silvia Nica

17 December 2025

Background and Objectives: Trauma remains a leading global cause of preventable mortality, and outcome prediction tools are essential for both triage and resource allocation. Timely and effective medical response to trauma patients is of the essence....

  • Article
  • Open Access
242 Views
17 Pages

Effects of Invasive Solidago canadensis and Biochar on the Remediation of Soil Cd Contamination and Greenhouse Gas Emissions

  • Xiaokang Ni,
  • Yadi Yu,
  • Xi Liu,
  • Wanqing Nie,
  • Yuli Hu,
  • Jian Bai,
  • Ziyi Yan,
  • Wei Li,
  • Lifei Xiong and
  • Xixian Xie
  • + 7 authors

16 December 2025

Cadmium (Cd) contamination in agricultural soils threatens food security and exacerbates climate change through its impact on greenhouse gas (GHG) (CO2, N2O and CH4) emissions, in which N2O and CO2 are the dominant fluxes of the terrestrial carbon-ni...

  • Review
  • Open Access
731 Views
39 Pages

Memory in Psychiatric Disorders: A Review

  • Riccardo Gurrieri,
  • Matteo Gambini,
  • Gerardo Russomanno,
  • Federico Mucci,
  • Manuel Glauco Carbone,
  • Giorgia Sità,
  • Elena Pescini,
  • Sibilla Stagi,
  • Anna Chiara Casucci and
  • Diletta Mastrogiacomo
  • + 2 authors

16 December 2025

Memory constitutes a fundamental cognitive domain, and converging evidence suggests that its dysfunction represents a prominent, though not exclusive, transdiagnostic dimension across major psychiatric disorders. This review aimed to integrate neurob...

  • Article
  • Open Access
330 Views
18 Pages

Genetic Characterization of the Arabian Horse Population in Tunisia Using Microsatellites

  • Mariem Jlassi,
  • Iheb Dhifalli,
  • Hatem Ouled Ahmed,
  • Faten Lasfar,
  • Mohamed El Gtari and
  • Bayrem Jemmali

16 December 2025

The genetic diversity and population structure of Tunisian Arabian horses were assessed using highly polymorphic microsatellite markers, which are critical for conservation and breeding programs. Despite the cultural and economic importance of Arabia...

  • Perspective
  • Open Access
1,053 Views
29 Pages

16 December 2025

Fascia research suffers from definitional fragmentation, with no universal agreement about what fascia actually is, why it matters, or how to define it. Researchers often pursue lines of inquiry based on their existing expertise, yet traditional and...

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Life - ISSN 2075-1729