Reviewing the Landscape of Psychopharmacology

Dear Colleagues,

Psychopharmacology remains a rapidly evolving field, existing at the intersection of neuroscience, psychiatry, and pharmacology. Over recent decades, advances in neurobiology and neuroimaging have deepened our understanding of the mechanisms underlying psychiatric disorders and their pharmacological treatments. At the same time, new challenges have emerged, including the need to improve the safety profiles of existing psychotropic medications, to address off-label prescribing practices, and to develop more personalized and mechanistically informed therapeutic strategies.

This Special Issue aims to provide a comprehensive and critical overview of current trends, controversies, and innovations in psychopharmacology. We welcome contributions that explore the efficacy, safety, and mechanisms of action of psychotropic drugs, including antidepressants, mood stabilizers, antipsychotics, anxiolytics, and stimulants. Potential submissions may include narrative or systematic reviews, meta-analyses, conceptual papers, or original data-driven contributions with a strong translational or clinical focus.

Topics of interest include, but are not limited to, the following areas: the neurobiological underpinnings of drug action; real-world data on safety and tolerability; psychopharmacological interventions in mood and anxiety disorders; pharmacovigilance and long-term outcomes; and ethical or regulatory issues surrounding novel therapeutics. We also encourage submissions addressing underexplored populations, such as adults with neurodevelopmental conditions or those with psychiatric comorbidities.

By bringing together diverse perspectives and methodologies, this Special Issue seeks to map the evolving landscape of psychopharmacology and to highlight future directions for both research and clinical practice.

Prof. Dr. Luca Steardo
Guest Editor

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