Recent Advances in Bone Biology

Dear Colleagues,

Bone is a mineralized and viscous-elastic connective tissue that exerts several crucial functions in the human body, such as allowing locomotion, protecting internal organs, storing and releasing fat, minerals, and hormones, producing blood cells, and providing mechanical support. Bone homeostasis is maintained through the finely tuned and regulated activities of bone cells, including osteogenic precursors, bone-forming osteoblasts, bone-resorbing osteoclasts, and mechanosensing osteocytes. Thanks to recently developed techniques in molecular and cellular biology, a deeper knowledge of bone cell physiology and pathophysiology has been achieved, allowing researchers and clinicians to better understand the mechanisms regulating bone homeostasis and to tackle bone diseases through innovative approaches. In this context, our aim for this Special Issue is to provide a comprehensive overview of recent theoretical, technical, and methodological advances in the field of bone biology. In particular, scientific contributions covering topics such as bone molecular and cellular biology, bone tissue development and repair, bone cell cross-talk, bone metabolism, bone signaling, bone cancer immunotherapy, bone-targeted therapies, the development of bone organoids for tissue engineering, and the mechanobiology of bone cells in in vitro and in vivo experimentations are welcome.

Dr. Barbara Peruzzi
Dr. Martina Leopizzi
Dr. Giulia Battafarano
Guest Editors

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