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Life, Volume 14, Issue 5

2024 May - 112 articles

Cover Story: The impact of SARS-CoV-2 extends beyond the respiratory system, notably affecting the vascular system with various adverse manifestations. The infection induces endothelial dysfunction and immune dysregulation, creating an inflammatory and hypercoagulable state. This affects both microvasculature and macrovasculature, leading to thromboembolic events, cardiovascular manifestations, impaired arterial stiffness, cerebrovascular complications, nephropathy, and retinopathy. The virus may lead to persistent vascular effects, characterized by prolonged inflammation, endotheliopathy, and an increased risk of vascular complications. This review aimed to comprehensively summarize the short and long-term vascular changes following COVID-19 infection, and provide an overview of preventive strategies to mitigate associated vascular complications. View this paper
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Articles (112)

  • Article
  • Open Access
11 Citations
5,815 Views
13 Pages

Evaluation of Cognitive Performance in Patients with Fibromyalgia Syndrome: A Case–Control Study

  • Francisco G. Fernández-Palacios,
  • Juan C. Pacho-Hernández,
  • César Fernández-de-las-Peñas,
  • Cristina Gómez-Calero and
  • Margarita Cigarán-Méndez

20 May 2024

Patients with fibromyalgia syndrome tend to report deficits in cognitive functions; however, there is no clear consensus on which cognitive domains are impaired. The aim of this study was to compare the differences in cognitive performance between a...

(This article belongs to the Section Medical Research)
  • Review
  • Open Access
9 Citations
3,725 Views
35 Pages

20 May 2024

Due to being sessile, plants develop a broad range of defense pathways when they face abiotic or biotic stress factors. Although plants are subjected to more than one type of stress at a time in nature, the combined effects of either multiple stresse...

(This article belongs to the Special Issue Plant Biotic and Abiotic Stresses 2024)
  • Article
  • Open Access
4 Citations
2,847 Views
16 Pages

20 May 2024

The moisture content of immersion vacuum-cooled sausages with modified casings containing citrus fruit extracts under different storage conditions was studied using hyperspectral imaging (HSI) associated with chemometrics. Different pre-processing co...

(This article belongs to the Special Issue Insights in Nutrition and Agri-Food Science Technology by Use of Smart Algorithm, Machine Learning, Multivariable and Omics Data Analysis)
  • Article
  • Open Access
17 Citations
3,394 Views
10 Pages

20 May 2024

The role of artificial intelligence (AI) in healthcare is evolving, offering promising avenues for enhancing clinical decision making and patient management. Limited knowledge about lipedema often leads to patients being frequently misdiagnosed with...

(This article belongs to the Special Issue Novel Approaches in Plastic and Reconstructive Surgery to Improve Quality of Life)
  • Article
  • Open Access
8 Citations
8,556 Views
12 Pages

Primary Hyperhidrosis in Children—A Retrospective Study and a Short Review

  • Florentina Nastase,
  • Madalina Codruta Verenca,
  • Elena Niculet,
  • Diana Sabina Radaschin,
  • Camelia Busila,
  • Claudiu Ionut Vasile and
  • Alin Laurentiu Tatu

19 May 2024

Primary hyperhidrosis (PH) is a relatively common chronic disorder, characterized by significant and uncontrollable sweating. The predominant areas of occurrence are hands, feet, head and armpits, and it affects both men and women equally, with a fal...

(This article belongs to the Special Issue Current Research on Dermatology: Pathology, Clinical Manifestation, Investigation and Therapy: 2nd Edition)
  • Article
  • Open Access
15 Citations
2,983 Views
12 Pages

19 May 2024

In this study, the 10-year cardiovascular risk associated with comorbid sleep disorders (insomnia disorder, obstructive sleep apnea syndrome, and COMISA [comorbid insomnia and sleep apnea]) was investigated for patients with major depression. To enab...

(This article belongs to the Special Issue Crosstalk between Cardiovascular Disease and Its Comorbidities)
  • Article
  • Open Access
8 Citations
2,997 Views
18 Pages

Epilactose as a Promising Butyrate-Promoter Prebiotic via Microbiota Modulation

  • Beatriz B. Cardoso,
  • Cláudia Amorim,
  • Ricardo Franco-Duarte,
  • Joana I. Alves,
  • Sónia G. Barbosa,
  • Sara C. Silvério and
  • Lígia R. Rodrigues

18 May 2024

Epilactose is a disaccharide composed of galactose and mannose, and it is currently considered an “under development” prebiotic. In this study, we described the prebiotic potential of epilactose by in vitro fermentation using human fecal...

(This article belongs to the Section Microbiology)
  • Communication
  • Open Access
3 Citations
3,829 Views
9 Pages

17 May 2024

Background: Implanted titanium skull plates (TSPs) in cranioplasty are used to replace or reconstruct areas of the skull that have been damaged or removed due to trauma, surgery, or other medical conditions. However, the presence of a TSP in the head...

(This article belongs to the Section Physiology and Pathology)
  • Article
  • Open Access
21 Citations
3,048 Views
20 Pages

Molecular Diversity and Combining Ability in Newly Developed Maize Inbred Lines under Low-Nitrogen Conditions

  • Mohamed M. Kamara,
  • Elsayed Mansour,
  • Ahmed E. A. Khalaf,
  • Mohamed A. M. Eid,
  • Abdallah A. Hassanin,
  • Ahmed M. Abdelghany,
  • Ahmed M. S. Kheir,
  • Ahmed A. Galal,
  • Said I. Behiry and
  • Salah El-Hendawy
  • + 1 author

17 May 2024

Nitrogen is an essential element for maize growth, but excessive application can lead to various environmental and ecological issues, including water pollution, air pollution, greenhouse gas emissions, and biodiversity loss. Hence, developing maize h...

(This article belongs to the Special Issue Effects of Environmental Factors on Challenges of Plant Breeding)
  • Review
  • Open Access
34 Citations
8,849 Views
34 Pages

Neurotoxicity of Some Environmental Pollutants to Zebrafish

  • Teodora Maria Buzenchi Proca,
  • Carmen Solcan and
  • Gheorghe Solcan

17 May 2024

The aquatic environment encompasses a wide variety of pollutants, from plastics to drug residues, pesticides, food compounds, and other food by-products, and improper disposal of waste is the main cause of the accumulation of toxic substances in wate...

(This article belongs to the Section Epidemiology)
  • Article
  • Open Access
4 Citations
2,380 Views
11 Pages

Valorization of Ginkgo biloba Leaf Powder as a Substrate in King Oyster Mushroom (Pleurotus eryngii) Cultivation

  • Haikang Li,
  • Peng Liu,
  • Zihao Li,
  • Congtao Xu,
  • Jinlong Pan,
  • Yi Zhou,
  • Qingxiu Hu,
  • Suyue Zheng and
  • Yajie Zou

17 May 2024

Ginkgo biloba is widely planted as a colorful foliage tree, and its leaf can be used as a biomass energy source, but it has been underutilized for a long time. The aim of this study was to investigate the potential of garden waste as a substrate comp...

(This article belongs to the Special Issue Research Progress of Cultivation of Edible Fungi)
  • Article
  • Open Access
4 Citations
3,275 Views
17 Pages

Interaction Studies of Hexameric and Pentameric IgMs with Serum-Derived C1q and Recombinant C1q Mimetics

  • Maria Magdalena John,
  • Monika Hunjadi,
  • Vanessa Hawlin,
  • Jean-Baptiste Reiser and
  • Renate Kunert

17 May 2024

The interaction between IgM and C1q represents the first step of the classical pathway of the complement system in higher vertebrates. To identify the significance of particular IgM/C1q interactions, recombinant IgMs were used in both hexameric and p...

(This article belongs to the Section Genomics and Proteomics)
  • Case Report
  • Open Access
1 Citations
4,839 Views
12 Pages

Myelodysplastic Syndrome: Clinical Characteristics and Significance of Preclinically Detecting Biallelic Mutations in the TET2 Gene

  • Anastasiia Danishevich,
  • Anzhelika Chegodar,
  • Natalia Bodunova,
  • Fedor Konovalov,
  • Maria Nefedova,
  • Natalya Kremneva,
  • Nizhat Kurbanov,
  • Airat Bilyalov,
  • Sergey Nikolaev and
  • Galina Dudina
  • + 1 author

16 May 2024

Myelodysplastic syndrome (MDS) is a clonal disease derived from hematopoietic stem cells, characterized by ineffective hematopoiesis (resulting in peripheral blood cytopenia) and an increased risk of transformation into acute myeloid leukemia. MDS is...

(This article belongs to the Section Medical Research)
  • Article
  • Open Access
4 Citations
3,105 Views
13 Pages

Alterations in Blood–Brain Barrier Integrity and Lateral Ventricle Differ in Rats Exposed to Space Radiation and Social Isolation

  • Austin M. Adkins,
  • Zachary N. M. Luyo,
  • Alayna J. Gibbs,
  • Alea F. Boden,
  • Riley S. Heerbrandt,
  • Justin D. Gotthold,
  • Richard A. Britten,
  • Laurie L. Wellman and
  • Larry D. Sanford

16 May 2024

The proposed Mars missions will expose astronauts to long durations of social isolation (SI) and space radiation (SR). These stressors have been shown to alter the brain’s macrostructure and microenvironment, including the blood–brain bar...

(This article belongs to the Special Issue Feature Paper in Physiology and Pathology)
  • Article
  • Open Access
3 Citations
2,283 Views
24 Pages

Association of Metallic and Nonmetallic Elements with Fibrin Clot Properties and Ischemic Stroke

  • Hieronim Jakubowski,
  • Marta Sikora,
  • Ewa Bretes,
  • Joanna Perła-Kaján,
  • Olga Utyro,
  • Izabela Wojtasz,
  • Radosław Kaźmierski,
  • Marcin Frankowski and
  • Anetta Zioła-Frankowska

16 May 2024

Objectives—Metallic elements and fibrin clot properties have been linked to stroke. We examined metallic and nonmetallic elements, fibrin clot lysis time (CLT), and maximum absorbance (Absmax) in relation to ischemic stroke. Design—A case...

(This article belongs to the Section Medical Research)
  • Article
  • Open Access
11 Citations
5,835 Views
12 Pages

Comparison of the Effects of Pilates and Yoga Exercise on the Dynamic Balancing Ability and Functional Movement of Fencers

  • So-Jung Lim,
  • Hyun-Jin Kim,
  • Yong-Soo Kim,
  • Eunkuk Kim,
  • Inyoung Hwang and
  • Ju-Seop Kang

16 May 2024

This study was conducted to compare and analyze whether Pilates exercise and yoga exercise help improve the performance of female fencers and prevent injury, and the dynamic balance test (LQ-YBT) and functional movement screening (FMS) test score of...

(This article belongs to the Special Issue Effects of Exercise Training on Muscle Function)
  • Article
  • Open Access
3 Citations
3,518 Views
11 Pages

B–NHL Cases in a Tertiary Pediatric Hematology—Oncology Department: A 20-Year Retrospective Cohort Study

  • Ioannis Kyriakidis,
  • Iordanis Pelagiadis,
  • Maria Stratigaki,
  • Nikolaos Katzilakis and
  • Eftichia Stiakaki

16 May 2024

Non-Hodgkin lymphoma (NHL) is among the five most common pediatric cancer diagnoses in children and adolescents and consists of a heterogeneous group of lymphoid tissue malignancies –with B-cell-derived NHL accounting for nearly 80% of cases. N...

(This article belongs to the Section Physiology and Pathology)
  • Article
  • Open Access
11 Citations
3,132 Views
29 Pages

Assessment of Phytomass and Carbon Stock in the Ecosystems of the Central Forest Steppe of the East European Plain: Integrated Approach of Terrestrial Environmental Monitoring and Remote Sensing with Unmanned Aerial Vehicles

  • Vasiliy Slavskiy,
  • Sergey Matveev,
  • Sergey Sheshnitsan,
  • Daria Litovchenko,
  • Maxim Viktorovich Larionov,
  • Anton Shokurov,
  • Pavel Litovchenko and
  • Nikolay Durmanov

15 May 2024

The rapid and accurate estimation of aboveground forest phytomass remains a challenging research task. In general, methods for estimating phytomass fall mainly into the category of field measurements performed by ground-based methods, but approaches...

(This article belongs to the Special Issue Elements Cycling and Plants’ Physiological Characteristics: A Soil–Plant–Atmosphere Continuum Perspective)
  • Article
  • Open Access
12 Citations
4,822 Views
20 Pages

A Clinical Study of Urine Amino Acids in Children with Autism Spectrum Disorder

  • Cătălina Mihaela Anastasescu,
  • Veronica Gheorman,
  • Florica Popescu,
  • Mioara Desdemona Stepan,
  • Eugen Cristi Stoicănescu,
  • Victor Gheorman and
  • Ion Udriștoiu

15 May 2024

Amino acids are organic compounds that enter the protein structure, being involved in the proper functioning of the body. The role of amino acids in the onset of autism spectrum disorder (ASD) is yet to be established. Our aim was to identify correla...

(This article belongs to the Section Physiology and Pathology)
  • Article
  • Open Access
4 Citations
4,390 Views
32 Pages

Role of Natural Binding Proteins in Therapy and Diagnostics

  • Marco Eigenfeld,
  • Kilian F. M. Lupp and
  • Sebastian P. Schwaminger

15 May 2024

This review systematically investigates the critical role of natural binding proteins (NBPs), encompassing DNA-, RNA-, carbohydrate-, fatty acid-, and chitin-binding proteins, in the realms of oncology and diagnostics. In an era where cancer continue...

(This article belongs to the Special Issue Revolutionizing Drug Delivery: Innovations in Targeted Therapeutic Nanocarriers)
  • Article
  • Open Access
3 Citations
6,148 Views
15 Pages

What Is New about the Semimembranosus Distal Tendon? Ultrasound, Anatomical, and Histological Study with Clinical and Therapeutic Application

  • Pere Iglesias-Chamorro,
  • Albert Pérez-Bellmunt,
  • Sara Ortiz-Miguel,
  • Ingrid Möller,
  • Juan Blasi,
  • Juan Ortiz-Sagristà,
  • Carlo Martinoli,
  • Xavier Sanjuan and
  • Maribel Miguel-Pérez

15 May 2024

The semimembranosus muscle inserts into several tendons that are associated with some pathologies. Although ultrasound is useful for studying, diagnosing, and managing these pathologies, the correct interpretation of any images requires a clear knowl...

(This article belongs to the Special Issue Topographic and Functional Anatomy of Musculoskeletal System)
  • Article
  • Open Access
4,172 Views
11 Pages

Prenatal Diagnosis of Fryns Syndrome through Identification of Two Novel Splice Variants in the PIGN Gene—A Case Series

  • Aruna Marchetto,
  • Susanne Leidescher,
  • Theresia van Hoi,
  • Niklas Hirschberger,
  • Florian Vogel,
  • Siegmund Köhler,
  • Ivonne Alexandra Bedei,
  • Roland Axt-Fliedner,
  • Moneef Shoukier and
  • Corinna Keil

14 May 2024

Fryns syndrome (FS) is a multiple congenital anomaly syndrome with different multisystemic malformations. These include congenital diaphragmatic hernia, pulmonary hypoplasia, and craniofacial dysmorphic features in combination with malformations of t...

(This article belongs to the Section Reproductive and Developmental Biology)
  • Review
  • Open Access
15 Citations
10,192 Views
12 Pages

Ocular Manifestation in Systemic Sclerosis—A Literature Review

  • Katarzyna Paczwa,
  • Magdalena Rerych,
  • Katarzyna Romanowska-Próchnicka,
  • Radosław Różycki and
  • Joanna Gołębiewska

13 May 2024

Systemic sclerosis (SSc) is a chronic autoimmune connective tissue disease that affects more than 2 million people worldwide. It manifests through vasculopathy, an abnormal immunological response, and fibrosis leading to dysfunction of the multiple o...

(This article belongs to the Section Physiology and Pathology)
  • Editorial
  • Open Access
3,000 Views
3 Pages

13 May 2024

In our pursuit of understanding the intricacies of microbial life, the isolation and characterization of new microbial species and strains play a pivotal role [...]

(This article belongs to the Collection Isolation and Characterization of New Microbial Species and Strains)
  • Article
  • Open Access
5 Citations
3,121 Views
31 Pages

12 May 2024

Familial Alzheimer’s disease (FAD) can be caused by mutations in PSEN1 that encode presenilin-1, a component of the gamma-secretase complex that cleaves amyloid precursor protein. Alterations in calcium (Ca2+) homeostasis and glutamate signalin...

(This article belongs to the Special Issue Ion Channels and Neurological Disease)
  • Article
  • Open Access
3 Citations
2,653 Views
14 Pages

Oxidative Stress, Persistent Inflammation and Blood Coagulation Alterations in Serum Proteome of Patients with Neovascular Age-Related Macular Degeneration

  • Mateusz Winiarczyk,
  • Bernd Thiede,
  • Tor Paaske Utheim,
  • Kai Kaarniranta,
  • Dagmara Winiarczyk,
  • Katarzyna Michalak and
  • Jerzy Mackiewicz

12 May 2024

Neovascular age-related macular degeneration (AMD) is a major cause of irreversible blindness in elderly populations in developed countries. AMD’s etiopathology is multifactorial, with strong environmental and genetic components, but the exact...

(This article belongs to the Special Issue Eye Diseases: Diagnosis and Treatment, 2nd Edition)
  • Article
  • Open Access
3,231 Views
13 Pages

11 May 2024

This retrospective cohort study evaluates the safety and efficacy of replacement therapy with regard to pregnancy outcomes in hemophilia carriers. Hemophilia carriers face elevated bleeding risks during pregnancy, necessitating meticulous management,...

(This article belongs to the Special Issue Hemophilia)
  • Article
  • Open Access
2 Citations
3,015 Views
28 Pages

Endophenotypes of Primary Osteoarthritis of the Hip Joint in the Bulgarian Population over 60 Years Old

  • Lyubomir Sapundzhiev,
  • Tanya Sapundzhieva,
  • Kamen Klinkanov,
  • Martin Mitev,
  • Kiril Simitchiev and
  • Anastas Batalov

11 May 2024

Aim. To identify subgroups of patients with primary osteoarthritis of the hip joint (pHOA) with similar imaging and laboratory findings, disease evolution, and response to conventional therapies. Methods. We performed further statistical analyses on...

(This article belongs to the Section Medical Research)
  • Article
  • Open Access
7 Citations
3,080 Views
13 Pages

Risk of Atrial Fibrillation in Patients with Different Cancer Types in Taiwan

  • Kuang-Ming Liao,
  • Chia-Hung Yu,
  • Yu-Cih Wu,
  • Jhi-Joung Wang,
  • Fu-Wen Liang and
  • Chung-Han Ho

11 May 2024

Atrial fibrillation (AF) commonly occurs in approximately 2% of cancer patients, and the incidence of AF among cancer patients is greater than in the general population. This observational study presented the incidence risk of AF among cancer patient...

(This article belongs to the Section Epidemiology)
  • Review
  • Open Access
23 Citations
13,417 Views
36 Pages

Dried Plasma for Major Trauma: Past, Present, and Future

  • Henry T. Peng,
  • Kanwal Singh,
  • Shawn G. Rhind,
  • Luis da Luz and
  • Andrew Beckett

10 May 2024

Uncontrollable bleeding is recognized as the leading cause of preventable death among trauma patients. Early transfusion of blood products, especially plasma replacing crystalloid and colloid solutions, has been shown to increase survival of severely...

(This article belongs to the Section Medical Research)
  • Article
  • Open Access
17 Citations
6,927 Views
18 Pages

10 May 2024

Scopolamine and atropine are two medicinal alkaloids derived from Datura stramonium L. with anticholinergic properties. This study explored how methyl jasmonate (MJ), a plant growth regulator, affects the biosynthesis and accumulation of these alkalo...

(This article belongs to the Section Genomics and Proteomics)
  • Review
  • Open Access
6 Citations
5,413 Views
21 Pages

Vitamin D: A Bridge between Kidney and Heart

  • Carmine Secondulfo,
  • Valeria Visco,
  • Nicola Virtuoso,
  • Martino Fortunato,
  • Serena Migliarino,
  • Antonella Rispoli,
  • Lucia La Mura,
  • Adolfo Stellato,
  • Giuseppe Caliendo and
  • Giancarlo Bilancio
  • + 3 authors

10 May 2024

Chronic kidney disease (CKD) and cardiovascular disease (CVD) are highly prevalent conditions, each significantly contributing to the global burden of morbidity and mortality. CVD and CKD share a great number of common risk factors, such as hypertens...

(This article belongs to the Section Medical Research)
  • Review
  • Open Access
6 Citations
5,334 Views
14 Pages

Fertility Preservation in BRCA1/2 Germline Mutation Carriers: An Overview

  • Erica Silvestris,
  • Gennaro Cormio,
  • Vera Loizzi,
  • Giacomo Corrado,
  • Francesca Arezzo and
  • Easter Anna Petracca

10 May 2024

BRCA1 and BRCA2 mutations are responsible for a higher incidence of breast and ovarian cancer (from 55% up to 70% vs. 12% in the general population). If their functions have been widely investigated in the onset of these malignancies, still little is...

(This article belongs to the Section Reproductive and Developmental Biology)
  • Review
  • Open Access
13 Citations
15,032 Views
15 Pages

Is It Possible to Train the Endothelium?—A Narrative Literature Review

  • Karolina Biernat,
  • Natalia Kuciel,
  • Justyna Mazurek and
  • Katarzyna Hap

10 May 2024

This review provides an overview of current knowledge regarding the adaptive effects of physical training on the endothelium. The endothelium plays a crucial role in maintaining the health of vessel walls and regulating vascular tone, structure, and...

(This article belongs to the Section Cell Biology and Tissue Engineering)
  • Systematic Review
  • Open Access
9 Citations
4,048 Views
11 Pages

Imipenem/Cilastatin/Relebactam for Complicated Infections: A Real-World Evidence

  • Pasquale Sansone,
  • Luca Gregorio Giaccari,
  • Giusy Di Flumeri,
  • Maria Caterina Pace,
  • Vincenzo Pota,
  • Francesco Coppolino,
  • Simona Brunetti and
  • Caterina Aurilio

10 May 2024

(1) Background: Infections caused by multidrug-resistant (MDR) bacteria represent one of the major global public health problems of the 21st century. Beta-lactam antibacterial agents are commonly used to treat infections due to Gram-negative pathogen...

(This article belongs to the Special Issue Trends in Microbiology 2024)
  • Case Report
  • Open Access
2 Citations
2,504 Views
14 Pages

10 May 2024

Tumoral calcinosis is an extremely rare genetic disease caused by mutations in three genes, GALNT3, FGF23, and KL, which disrupt phosphorus metabolism. The hallmark of this condition is the formation of tumors in the soft tissues around the joints. O...

(This article belongs to the Section Medical Research)
  • Article
  • Open Access
20 Citations
6,845 Views
11 Pages

10 May 2024

For patients with chronic pain and persistent physical symptoms, understanding the mechanism of central sensitisation may help in understanding how symptoms persist. This cross-sectional study investigated the association of central sensitisation wit...

(This article belongs to the Section Epidemiology)
  • Article
  • Open Access
12 Citations
3,163 Views
15 Pages

9 May 2024

Resveratrol, a polyphenolic compound found primarily in red grapes and pomegranates is known as an antioxidant but can act as a pro-oxidant when copper ions are present. Here, resveratrol is demonstrated to reduce cell growth (as evaluated by MTT ass...

(This article belongs to the Section Pharmaceutical Science)
  • Article
  • Open Access
7 Citations
2,385 Views
13 Pages

9 May 2024

Multidrug-resistant bacterial pathogens, such as E. coli, represent a major human health threat. Due to the critical need to overcome this dilemma, since the drug efflux pump has a vital function in the evolution of antimicrobial resistance in bacter...

(This article belongs to the Topic Plant Extracts and Their Therapeutic Effects)
  • Article
  • Open Access
7 Citations
5,854 Views
10 Pages

Non-Cicatricial Alopecia and Its Association with Anthropometric Measurements and Nutritional Laboratory Markers

  • Katarzyna Wróblewska-Kończalik,
  • Mariola Pawlaczyk,
  • Jerzy Kolasiński,
  • Małgorzata Kolenda,
  • Izabela Miechowicz,
  • Agnieszka Seraszek-Jaros,
  • Anna Kroma-Szal and
  • Justyna Gornowicz-Porowska

9 May 2024

Alopecia constitutes one of the most common dermatological disorders, and its steadily increasing prevalence is a cause for concern. Alopecia can be divided into two main categories, cicatricial/scarring and non-cicatricial/non-scarring, depending on...

(This article belongs to the Special Issue Current Research on Dermatology: Pathology, Clinical Manifestation, Investigation and Therapy: 2nd Edition)
  • Article
  • Open Access
4 Citations
3,075 Views
10 Pages

9 May 2024

Introduction: Non-infectious erythema, or Red Breast Syndrome (RBS), has been observed on the skin where acellular dermal matrix was implanted, although the exact cause is yet to be determined. Patients and Methods: A total of 214 female patients und...

(This article belongs to the Special Issue Advances in Breast Cancer Research and Treatment)
  • Review
  • Open Access
18 Citations
5,755 Views
18 Pages

The Winding Road from Origin to Emergence (of Life)

  • Wolfgang Nitschke,
  • Orion Farr,
  • Nil Gaudu,
  • Chloé Truong,
  • François Guyot,
  • Michael J. Russell and
  • Simon Duval

9 May 2024

Humanity’s strive to understand why and how life appeared on planet Earth dates back to prehistoric times. At the beginning of the 19th century, empirical biology started to tackle this question yielding both Charles Darwin’s Theory of Ev...

(This article belongs to the Special Issue Feature Papers in Origins of Life 2024)
  • Article
  • Open Access
10 Citations
2,773 Views
21 Pages

Genistein–Aspirin Combination Exerts Cytotoxic and Anti-Migratory Effects in Human Colorectal Cancer Cells

  • Claudia Iftode,
  • Stela Iurciuc,
  • Iasmina Marcovici,
  • Ioana Macasoi,
  • Dorina Coricovac,
  • Cristina Dehelean,
  • Sorin Ursoniu,
  • Andreea Rusu and
  • Simona Ardelean

9 May 2024

Colorectal cancer (CRC) is a heterogenous pathology with high incidence and mortality rates globally, but it is also preventable so finding the most promising candidates (natural compounds or repurposed drugs) to be chemopreventive alternatives has b...

(This article belongs to the Special Issue Natural Bioactives: Exploring Their Therapeutic Potential)
  • Article
  • Open Access
3 Citations
2,648 Views
11 Pages

9 May 2024

The aim of this study was to conduct salivary, microbiological, and caries risk assessments in relation to caries experience among individuals with intellectual disability in an institutional center in the Al-Baha region, Saudi Arabia. A cross-sectio...

(This article belongs to the Special Issue Trends in Microbiology 2024)
  • Article
  • Open Access
14 Citations
4,281 Views
16 Pages

The Efficiency of Kinesiotherapy versus Physical Modalities on Pain and Other Common Complaints in Fibromyalgia

  • Daniela Matei,
  • Rodica Trăistaru,
  • Vlad Pădureanu,
  • Taina Elena Avramescu,
  • Daniela Neagoe,
  • Amelia Genunche and
  • Anca Amzolini

8 May 2024

Due to its variety of signs and symptoms, there have been numerous attempts to treat fibromyalgia (FM), but a cure has yet to be established. The aim of this study was to evaluate the effects of a complex kinetic therapy program and a combined physic...

(This article belongs to the Special Issue Effects of Exercise Training on Muscle Function)
  • Article
  • Open Access
3 Citations
2,267 Views
9 Pages

Everolimus Treatment for Chronic Lung Allograft Dysfunction in Lung Transplantation

  • David Iturbe-Fernández,
  • Alicia de Pablo Gafas,
  • Víctor Manuel Mora Cuesta,
  • Rodrigo Alonso Moralejo,
  • Carlos Andrés Quezada Loaiza,
  • Virginia Pérez González,
  • Daniel López-Padilla and
  • José M. Cifrián

8 May 2024

Our study aims to evaluate the effect of everolimus treatment on lung function in lung transplant (LT) patients with established chronic lung allograft dysfunction (CLAD). Methods: This retrospective study included LT patients in two reference LT uni...

(This article belongs to the Section Medical Research)
  • Article
  • Open Access
8 Citations
2,226 Views
16 Pages

8 May 2024

Forests appeared during the Middle to Late Devonian, but Devonian forests and their compositions are still rarely known. Xinhang forest was reported as the largest Devonian forest, with lycopsid trees of Guangdedendron micrum Wang et al. A fern-like...

(This article belongs to the Section Paleobiology)
  • Article
  • Open Access
5 Citations
3,129 Views
13 Pages

New Estimates of Nitrogen Fixation on Early Earth

  • Madeline Christensen,
  • Danica Adams,
  • Michael L. Wong,
  • Patrick Dunn and
  • Yuk L. Yung

8 May 2024

Fixed nitrogen species generated by the early Earth’s atmosphere are thought to be critical to the emergence of life and the sustenance of early metabolisms. A previous study estimated nitrogen fixation in the Hadean Earth’s N2/CO2-domina...

(This article belongs to the Special Issue Feature Papers in Origins of Life)
  • Article
  • Open Access
6 Citations
3,269 Views
14 Pages

Phage Biosensor for the Classification of Metastatic Urological Cancers from Urine

  • Vilhelmiina Juusti,
  • Antti Rannikko,
  • Anu Laurila,
  • Maria Sundvall,
  • Pekka Hänninen and
  • Janne Kulpakko

8 May 2024

Most of the annual 10 million cancer-related deaths are caused by metastatic disease. Survival rates for cancer are strongly dependent on the type of cancer and its stage at detection. Early detection remains a challenge due to the lack of reliable b...

(This article belongs to the Section Biochemistry, Biophysics and Computational Biology)

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Life - ISSN 2075-1729