Crosstalk between Cardiovascular Disease and Its Comorbidities
A special issue of Life (ISSN 2075-1729). This special issue belongs to the section "Physiology and Pathology".
Deadline for manuscript submissions: closed (14 June 2024) | Viewed by 8593
Special Issue Editors
Interests: ischemic heart disease; arterial hypertension; pulmonary embolism; heart failure; biomarkers
Special Issues, Collections and Topics in MDPI journals
Interests: cardiovascular disease; atherosclerosis; arterial thrombosis; venous thrombosis; anticoagulants; hereditary thrombophilia; inflammation
Special Issues, Collections and Topics in MDPI journals
Special Issue Information
Dear Colleagues,
As our knowledge of the physiological and pathophysiological processes that take place in the human body deepens, we are also gaining a deeper awareness of their complexity. We now know that the activation and/or inactivation of multiple mechanisms and the chains of biological events that take place in an organ can have impacts of variable intensity on other organs and systems.
This interdependence is especially evident in diseases of the cardiovascular system. Metabolic disorders, such as dyslipidemia and diabetes; conditions associated with vascular injuries, such as chronic kidney disease; or chemotherapy and chest radiotherapy for patients with various neoplasms are just a few triggers of cardiovascular disease. Moreover, the presence of cardiovascular disease, especially in its most severe form—heart failure—has major consequences for all organs and systems, such as the kidneys, liver and brain, leading to their rapid dysfunction. This interplay causes a downward spiral of progressive and reciprocal aggravation that leads inexorably to early death.
Thus, the diagnosis and treatment of cardiovascular disease, aside from targeting the primary disease, must also seek to actively manage its comorbidities. This is sometimes difficult to achieve, because early dysfunction is subclinical, reflected in adaptive structural or humoral changes that can only be highlighted by imaging or laboratory methods. Moreover, these adaptive changes are the expression of long-term disturbances at the infracellular level. Their identification is becoming an essential pillar of modern medicine, as it could lead to early treatment before irreversible structural and functional changes occur, especially symptomatic ones.
This Special Issue invites you to share research on the diagnosis and treatment of cardiovascular diseases in patients with comorbidities, where the accumulation of disturbances requires diagnostic and therapeutic management on multiple levels. We are interested in both original articles and reviews, with the aim of improving the management of patients with cardiovascular disease and its comorbidities, which are both difficult to treat and frequently encountered in current practice.
Prof. Dr. Irina Iuliana Costache
Dr. Minerva Codruta Badescu
Guest Editors
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Keywords
- cardiovascular
- comorbidities
- diabetes
- obesity
- dyslipidemia
- chronic kidney disease
- cancer
- lung disease
- liver disease
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