2026 October - 186 articles
Thoracic and abdominal aortic aneurysms (TAA and AAA) progress silently, and no drug has been shown to slow their growth. Circulating lipids, statins, and metformin are candidate disease modifiers, but the evidence is heterogeneous and largely observ...
Background: Airway function in children with adrenal insufficiency (AI) has not been well characterized. We evaluated impulse oscillometry (IOS) findings in pediatric AI and compared patients with congenital adrenal hyperplasia (CAH) and AI due to ca...
Climate-related hazards are associated with adverse mental and physical health outcomes, but exposure-specific human findings are often discussed together with general stress mechanisms without clearly distinguishing their evidentiary strength. This...
This study examined exploratory associations between isokinetic knee and hip variables and video-derived contact time across sprint acceleration. Nineteen male sprinters completed 60 m sprints; photocell timing gates recorded sprint times, and eight...
The channel TRPM2 forms cation-selective channels and is activated by redox-dynamics, including oxidative stress. Initially described at the plasma membrane, TRPM2 has been found to also localized to intracellular compartments, i.e., nucleus, mitocho...
High-risk human papillomavirus (HR-HPV) genotypes differ in their oncogenic potential and contribution to cervical precancer and invasive cancer. We investigated temporal changes in HR-HPV genotype patterns in histologically confirmed cervical high-g...
Background: Percutaneous transhepatic biliary drainage (PTBD) remains a cornerstone in managing obstructive jaundice, particularly when endoscopic retrograde cholangiopancreatography (ERCP) is unsuccessful or contraindicated. This study aims to compa...
Background: Relative humidity is an important meteorological factor that has received considerably less attention than temperature and atmospheric pressure regarding its effects on human health. This study investigated the association between environ...
Pseudomonas syringae pv. tomato DC3000 (Pst DC3000) is a reference system for dissecting how type III-secreted effectors (T3Es) suppress plant immunity and reconfigure host physiology. Here, we reassess the DC3000 effector repertoire through an evide...
Drug-coated balloon (DCB) therapy differs fundamentally from stent-based revascularization since the vessel itself becomes the treatment substrate. Consequently, vascular preparation is an important component of DCB therapy. This review therefore exa...
Atherosclerosis is the principal underlying pathology of cardiovascular diseases (CVDs), with endothelial dysfunction representing one of the earliest events in its initiation and progression. Oxidised low-density lipoprotein (oxLDL) plays a pivotal...
Background: Glibenclamide remains widely used for glycemic control in type 2 diabetes mellitus (T2DM), but its comparative metabolic effects across glycemic, lipid, anthropometric, and cardiometabolic outcomes remain uncertain. We conducted a systema...
Acute pancreatitis (AP) is an acute inflammatory disorder of the pancreas that disrupts its normal function and often requires hospitalization because of severe abdominal pain. While most patients recover without major complications, some develop pan...
Molecular subtypes from multi-omic profiling have refined the biological characterization of clear cell renal cell carcinoma (ccRCC), but whether they add prognostic information to clinicopathological variables already in use is unclear. We evaluated...
Toxic elements (TEs) are widespread environmental contaminants that act as systemic toxicants and are recognized contributors to atherosclerotic cardiovascular disease (ASCVD) morbidity and mortality, posing significant health risks even at low level...
Background and Objectives: Hyaluronan-enriched embryo transfer media have been proposed to improve implantation and reproductive outcomes; however, their clinical benefit remains uncertain, particularly in frozen embryo transfer cycles. This study ai...
Late-onset Alzheimer’s disease (LOAD) is increasingly recognized as a complex, multifactorial disorder driven by the convergence of genetic susceptibility and interconnected molecular pathways, rather than a single linear pathogenic cascade. In...
Obstructive sleep apnea (OSA) is a prevalent disorder for which accessible non-invasive screening approaches remain of interest. This study evaluated photographic craniofacial descriptors and speech-derived acoustic features for Apnea–Hypopnea...
Plasmablastic/anaplastic plasma cell neoplasms (P/APC-N) and plasmablastic lymphoma (PBL) represent two categories of highly aggressive hematolymphoid malignancies. Their distinction is clinically important because they are classified and treated wit...
Glucolipotoxic stress contributes to diabetic muscle atrophy by disrupting myoblast homeostasis and myogenesis-associated responses. Fullerol is a water-soluble polyhydroxylated fullerene derivative with potent free-radical-scavenging activity. We in...
Verbenaceae are prominent components of cultivated and human-influenced landscapes, yet their taxonomic and horticultural diversity and relationships with local plant knowledge remain poorly documented in Buri Ram Province, Thailand. This study provi...
Background: Prognostic gene expression signatures in colorectal cancer are usually reported by standalone discrimination, a standard that random gene sets can meet, and are rarely tested for what they add to routine clinical variables. Methods: TCGA-...
Thyroid cancer is treated by a combination of surgical treatment in the form of thyroidectomy, administration of radioactive iodine and subsequent administration of thyroxine. The aim of radioactive iodine administration in differentiated thyroid car...
Iron deficiency remains a major public health challenge in populations relying on staple foods with low iron bioavailability, including polished rice. This narrative review evaluates how beneficial plant-associated microorganisms may support iron (Fe...
Introduction: Alzheimer’s disease (AD) has progressive structural brain changes that can be described using magnetic resonance imaging (MRI). Previous work has used several statistical approaches to compare the volume of brain regions such as t...
The manufacturing of placenta- and umbilical cord-derived mesenchymal stromal cells (MSCs) varies across anatomical starting material, isolation, culture supplementation, expansion, scale-up, cryopreservation, and release testing. This variability li...
Peripheral arterial disease (PAD) is a manifestation of systemic atherosclerosis in which chronic inflammation contributes to disease severity. This retrospective study included patients who underwent arteriography for PAD at a single center in 2019....
Among uterus-preserving treatments for presumed fibroids, only myomectomy yields a specimen. Occult uterine sarcoma is uncommon, but leiomyosarcoma is clinically aggressive and seldom recognised before treatment. This narrative review examines what p...
(1) Background: Oxidative stress-induced endothelial senescence is associated with mitochondrial dysfunction, impaired mitochondrial quality control, and pro-inflammatory signaling. We examined whether extracellular vesicles (EVs) derived from epigal...
Background: Vascular rings are rare congenital developmental anomalies of the cardiovascular system that present with variable respiratory and gastrointestinal symptoms often refractory to what is considered a standard treatment. The aim of our study...
Cognitive impairment is a major public health concern, and the liver–brain axis has attracted growing interest. Gamma-glutamyl transferase (GGT) is a serum marker of liver function, but its association with cognitive outcomes remains uncertain....
This study examined the response of osteoblast-like cells to siloxane-based biohybrid materials obtained via the sol–gel process and modified with titania or with titania and calcium. The biohybrids’ ability to form apatite and their degr...
Chronic diseases represent a substantial public health burden, motivating the development of transparent and reproducible approaches for disease-specific risk prediction using routinely available lifestyle and clinical variables. This study presents...
Automated sperm morphology classification can reduce the subjectivity and workload of manual microscopic assessment, but limited benchmark data and subtle morphology-related visual differences remain important challenges. This study proposes a domain...
The assessment of left and right ventricular systolic function is vital information for the management of cardiac disease. Everyday clinical practice has traditionally relied on the measurement of the ejection fraction (EF). Nonetheless, EF has known...
Species of the genus Auricularia (wood ear mushrooms) are among the most economically important edible and medicinal mushrooms worldwide, particularly in Asia. Although numerous studies have investigated their taxonomy, cultivation practices, and bio...
In the context of chronic obstructive pulmonary disease (COPD), understanding gene expression patterns across various cell types is pivotal for disease comprehension, therapeutic development, and enhancement of patient prognosis. Nevertheless, the in...
Thaicypridopsis is rare and endemic to Thailand, appearing as a monospecific genus since its discovery. The recent investigation of ostracods in northeast Thailand, together with the reexamination of collections from other parts, including the poorly...
Acetogenins (ACGs) are bioactive compounds typically found in the Annonaceae family, such as soursop (Annona muricata), and have demonstrated strong antineoplastic effects at very low doses across different cancer cell lines. However, their poor wate...
Post-stroke dysphagia is a common complication of stroke. Quantitative ultrasonography has emerged as a noninvasive, radiation-free, and repeatable approach for evaluating swallowing-related structures and movements. This narrative review summarizes...
Circadian rhythms play a vital role in lipid metabolism by coordinating lipogenesis, lipolysis and fatty acid oxidation to maintain energy homeostasis. Their regulation is affected by light exposure, feeding time, dietary composition, hormonal signal...
Cardiovascular disease (CVD) remains a leading cause of morbidity and mortality worldwide, motivating data-driven tools that complement established clinical risk criteria. We present a two-pathway machine learning framework for CVD risk assessment. P...
Background: Small-bowel bleeding accounts for a minority of gastrointestinal hemorrhage and may pose a diagnostic challenge after negative bidirectional endoscopy. Malignant melanoma involving the small intestine is usually metastatic, whereas a true...
The podocyte is a terminally differentiated cell whose foot processes and slit diaphragm form the final layer of the glomerular filtration barrier. Because podocytes are not effectively replaced after birth, and nephron number is fixed before it, the...
Background/Objectives: Studies of socioeconomic differences in DNA methylation-based ageing mainly report regression coefficients, group contrasts, mediation estimates, or decompositions, which do not describe how complete epigenetic age acceleration...
Background: Persistent or recurrent periprosthetic joint infection after total knee arthroplasty is a devastating complication. When revision fails, knee arthrodesis remains an important limb-salvage option. Cement-based artificial arthrodesis may pr...
Precision sports such as archery require sustained attention, fine motor control, and technical consistency, all of which may be influenced by sleep quality. This cross-sectional study aimed to examine the association between sleep quality and shooti...
Background: Tooth loss is a cumulative oral-health outcome associated with reduced quality of life and several behavioral and systemic factors. Fewer studies have examined oral hygiene and multiple cardiovascular risk factors simultaneously in relati...
Reports of viable microorganisms from ancient halite create an unusual test of the biological limits of cellular survival. Halite deposits can be tens to hundreds of millions of years old, and increasingly rigorous studies have used chemical surface...
Pancreatic ductal adenocarcinoma (PDAC) has a five-year relative survival of 8%. Feature selection optimizes accuracy, survival concordance, and network structure separately; whether uniting them matters has not been determined. The BIMS-GA optimizes...
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