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Micromachines, Volume 11, Issue 1

2020 January - 111 articles

Cover Story: Biochemical assays targeting cells suspended in body fluids are clinically used for diagnoses or prognoses. However, performing assays using suspended cells involves important steps, such as purification and immobilization of target cells. In this paper, a sequential cell processing device, which is composed of pre-processing modules that employ deterministic lateral displacement and a single cell trapping device employing an electroactive microwell array, is proposed to perform the sample purification and medium exchange followed by arraying single cells for the downstream biochemical assays. View this paper.
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Articles (111)

  • Article
  • Open Access
7 Citations
4,598 Views
10 Pages

Tunable-Focus Liquid Lens through Charge Injection

  • Shizhi Qian,
  • Wenxiang Shi,
  • Huai Zheng and
  • Zhaohui Liu

20 January 2020

Liquid lenses are the simplest and cheapest optical lenses, and various studies have been conducted to develop tunable-focus liquid lenses. In this study, a simple and easily implemented method for achieving tunable-focus liquid lenses was proposed a...

  • Article
  • Open Access
11 Citations
5,685 Views
10 Pages

Dynamical Control of Broadband Coherent Absorption in ENZ Films

  • Vincenzo Bruno,
  • Stefano Vezzoli,
  • Clayton DeVault,
  • Thomas Roger,
  • Marcello Ferrera,
  • Alexandra Boltasseva,
  • Vladimir M. Shalaev and
  • Daniele Faccio

20 January 2020

Interferometric effects between two counter-propagating beams incident on an optical system can lead to a coherent modulation of the absorption of the total electromagnetic radiation with 100% efficiency even in deeply subwavelength structures. Coher...

  • Article
  • Open Access
9 Citations
3,468 Views
12 Pages

19 January 2020

Mainstream next generation electronic devices with miniaturized structures and high levels of performance are needed to meet the characteristic requirements of electronics with flexible and stretchable capabilities. Accordingly, several applied field...

  • Article
  • Open Access
22 Citations
6,188 Views
10 Pages

Real-Time Monitoring and Detection of Single-Cell Level Cytokine Secretion Using LSPR Technology

  • Chen Zhu,
  • Xi Luo,
  • Wilfred Villariza Espulgar,
  • Shohei Koyama,
  • Atsushi Kumanogoh,
  • Masato Saito,
  • Hyota Takamatsu and
  • Eiichi Tamiya

19 January 2020

Cytokine secretion researches have been a main focus of studies among the scientists in the recent decades for its outstanding contribution to clinical diagnostics. Localized surface plasmon resonance (LSPR) technology is one of the conventional meth...

  • Article
  • Open Access
9 Citations
4,855 Views
12 Pages

19 January 2020

Hydrogel-facilitated phase separation (HFPS) has recently been applied to make microstructured porous membranes by modified phase separation processes. In HFPS, a soft lithographically patterned hydrogel mold is used as a water content source that in...

  • Article
  • Open Access
30 Citations
5,317 Views
12 Pages

Smart Tactile Sensing Systems Based on Embedded CNN Implementations

  • Mohamad Alameh,
  • Yahya Abbass,
  • Ali Ibrahim and
  • Maurizio Valle

18 January 2020

Embedding machine learning methods into the data decoding units may enable the extraction of complex information making the tactile sensing systems intelligent. This paper presents and compares the implementations of a convolutional neural network mo...

  • Article
  • Open Access
6 Citations
4,035 Views
14 Pages

18 January 2020

We demonstrate freely suspended graphene-based nanomechanical membranes (NMMs) as acoustic sensors in the audible frequency range. Simple and low-cost procedures are used to fabricate NMMs with various thicknesses based on graphene layers grown by gr...

  • Article
  • Open Access
22 Citations
4,616 Views
9 Pages

18 January 2020

Over the past ten years, tissue engineering has witnessed significant technological and scientific advancements. Progress in both stem cell science and additive manufacturing have established new horizons in research and are poised to bring improveme...

  • Feature Paper
  • Article
  • Open Access
51 Citations
8,564 Views
16 Pages

A Robotic Biopsy Endoscope with Magnetic 5-DOF Locomotion and a Retractable Biopsy Punch

  • Manh Cuong Hoang,
  • Viet Ha Le,
  • Kim Tien Nguyen,
  • Van Du Nguyen,
  • Jayoung Kim,
  • Eunpyo Choi,
  • Seungmin Bang,
  • Byungjeon Kang,
  • Jong-Oh Park and
  • Chang-Sei Kim

17 January 2020

Capsule endoscopes (CEs) have emerged as an advanced diagnostic technology for gastrointestinal diseases in recent decades. However, with regard to robotic motions, they require active movability and multi-functionalities for extensive, untethered, a...

  • Feature Paper
  • Article
  • Open Access
12 Citations
5,257 Views
10 Pages

17 January 2020

We developed an innovative paper-based platform for high-throughput culturing, trapping, and monitoring of C. elegans. A 96-well array was readily fabricated by placing a nutrient-replenished paper substrate on a micromachined 96-well plastic frame,...

  • Article
  • Open Access
10 Citations
4,088 Views
14 Pages

Dye-Doped ZnO Microcapsules for High Throughput and Sensitive Optofluidic Micro-Thermometry

  • Najla Ghifari,
  • Sara Rassouk,
  • Zain Hayat,
  • Abdelhafed Taleb,
  • Adil Chahboun and
  • Abdel I. El Abed

17 January 2020

The main objective of this work is to show the proof of concept of a new optofluidic method for high throughput fluorescence-based thermometry, which enables the measure of temperature inside optofluidic microsystems at the millisecond (ms) time scal...

  • Article
  • Open Access
6 Citations
7,900 Views
9 Pages

Vertical Leakage in GaN-on-Si Stacks Investigated by a Buffer Decomposition Experiment

  • Alaleh Tajalli,
  • Matteo Borga,
  • Matteo Meneghini,
  • Carlo De Santi,
  • Davide Benazzi,
  • Sven Besendörfer,
  • Roland Püsche,
  • Joff Derluyn,
  • Stefan Degroote and
  • Gaudenzio Meneghesso
  • + 6 authors

17 January 2020

We investigated the origin of vertical leakage and breakdown in GaN-on-Si epitaxial structures. In order to understand the role of the nucleation layer, AlGaN buffer, and C-doped GaN, we designed a sequential growth experiment. Specifically, we analy...

  • Article
  • Open Access
35 Citations
6,167 Views
12 Pages

Mechanical Behavior Investigation of 4H-SiC Single Crystal at the Micro–Nano Scale

  • Peng Chai,
  • Shujuan Li,
  • Yan Li,
  • Lie Liang and
  • Xincheng Yin

17 January 2020

In this paper, theoretical models of the critical indentation depth and critical force on brittle materials using cleavage strength and contact theory are proposed. A Berkovich indenter is adopted for nanoindentation tests on a 4H-SiC single crystal...

  • Article
  • Open Access
9 Citations
3,575 Views
15 Pages

A Programmable Nanofabrication Method for Complex 3D Meta-Atom Array Based on Focused-Ion-Beam Stress-Induced Deformation Effect

  • Xiaoyu Chen,
  • Yuyu Xia,
  • Yifei Mao,
  • Yun Huang,
  • Jia Zhu,
  • Jun Xu,
  • Rui Zhu,
  • Lei Shi and
  • Wengang Wu

16 January 2020

Due to their unique electromagnetic properties, meta-atom arrays have always been a hotspot to realize all kinds of particular functions, and the research on meta-atom structure has extended from two-dimensions (2D) to three-dimensions (3D) in recent...

  • Article
  • Open Access
15 Citations
4,477 Views
15 Pages

16 January 2020

A micro-reciprocating piston internal combustion engine with liquid hydrocarbon fuel has the potential to supply ultrahigh density energy to micro electro mechanical system because of its high-density energy, simple structure, and mature energy conve...

  • Article
  • Open Access
4 Citations
3,557 Views
11 Pages

16 January 2020

In this paper, a novel gallium nitride (GaN)-based heterostructure Gunn diode is proposed for the first time to enhance the output characteristics of Gunn oscillation waveforms. A well-designed grooved anode contact is adopted to separate the long-ch...

  • Article
  • Open Access
42 Citations
5,697 Views
12 Pages

Low-Concentration Ammonia Gas Sensors Manufactured Using the CMOS–MEMS Technique

  • Wei-Chun Shen,
  • Po-Jen Shih,
  • Yao-Chuan Tsai,
  • Cheng-Chih Hsu and
  • Ching-Liang Dai

15 January 2020

This study describes the fabrication of an ammonia gas sensor (AGS) using a complementary metal oxide semiconductor (CMOS)–microelectromechanical system (MEMS) technique. The structure of the AGS features interdigitated electrodes (IDEs) and a...

  • Article
  • Open Access
13 Citations
3,789 Views
12 Pages

15 January 2020

Congo Red (CR) and Amido Black 10B (AB-10B) are anionic diazo dyes, which are metabolized to produce a bioaccumulative and persistent carcinogen, benzidine. In this regard, an angle sensitive sensor composed of photonic crystal supported photocatalys...

  • Feature Paper
  • Article
  • Open Access
37 Citations
8,143 Views
12 Pages

15 January 2020

Single-cell analysis is of critical importance in revealing cell-to-cell heterogeneity by characterizing individual cells and identifying minority sub-populations of interest. Droplet-based microfluidics has been widely used in the past decade to ach...

  • Article
  • Open Access
20 Citations
4,488 Views
19 Pages

System-Level Model and Simulation of a Frequency-Tunable Vibration Energy Harvester

  • Sofiane Bouhedma,
  • Yongchen Rao,
  • Arwed Schütz,
  • Chengdong Yuan,
  • Siyang Hu,
  • Fred Lange,
  • Tamara Bechtold and
  • Dennis Hohlfeld

14 January 2020

In this paper, we present a macroscale multiresonant vibration-based energy harvester. The device features frequency tunability through magnetostatic actuation on the resonator. The magnetic tuning scheme uses external magnets on linear stages. The s...

  • Article
  • Open Access
5 Citations
6,512 Views
9 Pages

Controlling Shapes in a Coaxial Flow Focusing Microfluidic Device: Experiments and Theory

  • Romen Rodriguez-Trujillo,
  • Yu-Han Kim-Im and
  • Aurora Hernandez-Machado

13 January 2020

A coaxial flow focusing PDMS (polydimethylsiloxane) microfluidic device has been designed and manufactured by soft lithography in order to experimentally study a miscible inner flow. We studied a coaxially focused inner flow (formed by an aqueous flu...

  • Article
  • Open Access
19 Citations
4,255 Views
16 Pages

Experimental Study on Machinability of Zr-Based Bulk Metallic Glass during Micro Milling

  • Tao Wang,
  • Xiaoyu Wu,
  • Guoqing Zhang,
  • Bin Xu,
  • Yinghua Chen and
  • Shuangchen Ruan

13 January 2020

The micro machinability of Zr41.2Ti13.8Cu12.5Ni10Be22.5 bulk metallic glass (BMG) was investigated by micro milling with coated cemented carbide tools. The corresponding micro milling tests on Al6061 were conducted for comparison. The results showed...

  • Article
  • Open Access
5 Citations
5,030 Views
8 Pages

Methacrylate Coatings for Titanium Surfaces to Optimize Biocompatibility

  • Argus Sun,
  • Nureddin Ashammakhi and
  • Mehmet R. Dokmeci

13 January 2020

Currently, there are more than 1.5 million knee and hip replacement procedures carried out in the United States. Implants have a 10–15-year lifespan with up to 30% of revision surgeries showing complications with osteomyelitis. Titanium and tit...

  • Article
  • Open Access
10 Citations
5,626 Views
11 Pages

13 January 2020

In this study, silicon nitride thin films are deposited on organic polyethylene-naphthalate (PEN) substrates by laser assisted plasma enhanced chemical vapor deposition (LAPECVD) at a low temperature (150 °C) for the purpose of evaluating the enc...

  • Article
  • Open Access
15 Citations
5,011 Views
11 Pages

A Novel Characterization and Performance Measurement of Memristor Devices for Synaptic Emulators in Advanced Neuro-Computing

  • AlaaDdin Al-Shidaifat,
  • Shubhro Chakrabartty,
  • Sandeep Kumar,
  • Suvojit Acharjee and
  • Hanjung Song

13 January 2020

The advanced neuro-computing field requires new memristor devices with great potential as synaptic emulators between pre- and postsynaptic neurons. This paper presents memristor devices with TiO2 Nanoparticles (NPs)/Ag(Silver) and Titanium Dioxide (T...

  • Communication
  • Open Access
23 Citations
4,457 Views
8 Pages

Auxiliary Optomechanical Tools for 3D Cell Manipulation

  • Ivan Shishkin,
  • Hen Markovich,
  • Yael Roichman and
  • Pavel Ginzburg

13 January 2020

Advances in laser and optoelectronic technologies have brought the general concept of optomechanical manipulation to the level of standard biophysical tools, paving the way towards controlled experiments and measurements of tiny mechanical forces. Re...

  • Review
  • Open Access
33 Citations
7,084 Views
20 Pages

Microfluidics Mediated Production of Foams for Biomedical Applications

  • Ilham Maimouni,
  • Cesare M. Cejas,
  • Janine Cossy,
  • Patrick Tabeling and
  • Maria Russo

12 January 2020

Within the last decade, there has been increasing interest in liquid and solid foams for several industrial uses. In the biomedical field, liquid foams can be used as delivery systems for dermatological treatments, for example, whereas solid foams ar...

  • Article
  • Open Access
32 Citations
4,014 Views
14 Pages

12 January 2020

This paper presents an adaptive hysteresis compensation approach for a piezoelectric actuator (PEA) using single-neuron adaptive control. For a given desired trajectory, the control input to the PEA is dynamically adjusted by the error between the ac...

  • Article
  • Open Access
61 Citations
7,231 Views
14 Pages

A Piezo-Electromagnetic Coupling Multi-Directional Vibration Energy Harvester Based on Frequency Up-Conversion Technique

  • Ge Shi,
  • Junfu Chen,
  • Yansheng Peng,
  • Mang Shi,
  • Huakang Xia,
  • Xiudeng Wang,
  • Yidie Ye and
  • Yinshui Xia

11 January 2020

Harvesting vibration energy to power wearable devices has become a hot research topic, while the output power and conversion efficiency of a vibration energy harvester with a single electromechanical conversion mechanism is low and the working freque...

  • Article
  • Open Access
15 Citations
3,867 Views
11 Pages

Synthesis and a Photo-Stability Study of Organic Dyes for Electro-Fluidic Display

  • Yong Deng,
  • Shi Li,
  • Dechao Ye,
  • Hongwei Jiang,
  • Biao Tang and
  • Guofu Zhou

11 January 2020

Electro-fluidic display (EFD) is one of the most promising reflective displays because of its full color and video speed. Colored EFD oil, which normally consists of soluble organic dyes and non-polar solvent, plays a critical role in color, electro-...

  • Article
  • Open Access
4 Citations
2,638 Views
8 Pages

11 January 2020

A set of empirical equations were developed to describe the optical properties of III-nitride dot-in-wire nanostructures. These equations depend only on the geometric properties of the structures, enabling the design process of a III-nitride light em...

  • Concept Paper
  • Open Access
26 Citations
4,404 Views
13 Pages

Sensitivity Comparison of Refractive Index Transducer Optical Fiber Based on Surface Plasmon Resonance Using Ag, Cu, and Bimetallic Ag–Cu Layer

  • Rozalina Zakaria,
  • Nur Aina’a Mardhiah Zainuddin,
  • Sofiah Athirah Raya,
  • Siti Anis Khairani Alwi,
  • Toni Anwar,
  • Aliza Sarlan,
  • Kawsar Ahmed and
  • Iraj Sadegh Amiri

10 January 2020

A single-mode optical fiber sensor uses surface plasmon resonance (SPR) with a bimetallic silver–copper (Ag–Cu) coating compared to a single layer of Ag and Cu itself. Bimetallic Ag–Cu sensors are constructed by simple fabrication o...

  • Feature Paper
  • Review
  • Open Access
17 Citations
4,871 Views
20 Pages

A Review on Optoelectrokinetics-Based Manipulation and Fabrication of Micro/Nanomaterials

  • Wenfeng Liang,
  • Lianqing Liu,
  • Junhai Wang,
  • Xieliu Yang,
  • Yuechao Wang,
  • Wen Jung Li and
  • Wenguang Yang

10 January 2020

Optoelectrokinetics (OEK), a fusion of optics, electrokinetics, and microfluidics, has been demonstrated to offer a series of extraordinary advantages in the manipulation and fabrication of micro/nanomaterials, such as requiring no mask, programmabil...

  • Brief Report
  • Open Access
21 Citations
6,832 Views
10 Pages

10 January 2020

Microfluidic devices are gaining increasing popularity due to their wide applications in various research areas. Herein, we propose a two-layer multi-channel microfluidic device allowing for direct-contact cell-vessel co-culture. Using the device, we...

  • Feature Paper
  • Article
  • Open Access
5 Citations
4,067 Views
13 Pages

9 January 2020

A seamless thin-walled hollow metallic cylinder with array of micro-perforations is one of the key components for some products. Normally, these micro-perforations are formed by removing material from the given metallic hollow cylinder (pipe or tube)...

  • Article
  • Open Access
44 Citations
4,535 Views
23 Pages

Collaboration and Task Planning of Turtle-Inspired Multiple Amphibious Spherical Robots

  • Liang Zheng,
  • Shuxiang Guo,
  • Yan Piao,
  • Shuoxin Gu and
  • Ruochen An

9 January 2020

Amphibious Spherical Robots (ASRs) use an electric field to communicate and collaborate effectively in a turbid water of confined spaces where other mode communication modalities failed. This paper proposes an embedded architecture formation strategy...

  • Feature Paper
  • Review
  • Open Access
51 Citations
9,682 Views
20 Pages

Photonic Crystal Nanobeam Cavities for Nanoscale Optical Sensing: A Review

  • Da-Quan Yang,
  • Bing Duan,
  • Xiao Liu,
  • Ai-Qiang Wang,
  • Xiao-Gang Li and
  • Yue-Feng Ji

9 January 2020

The ability to detect nanoscale objects is particular crucial for a wide range of applications, such as environmental protection, early-stage disease diagnosis and drug discovery. Photonic crystal nanobeam cavity (PCNC) sensors have attracted great a...

  • Editorial
  • Open Access
2,062 Views
3 Pages

9 January 2020

Computing systems are undergoing a transformation from logic-centric toward memory-centric architectures, where overall performance and energy efficiency at the system level are determined by the density, bandwidth, latency, and energy efficiency of...

  • Article
  • Open Access
17 Citations
4,756 Views
16 Pages

9 January 2020

This paper presents a novel multi-objective parameter optimization method based on the genetic algorithm (GA) and adaptive moment estimation (Adam) algorithm for the design of a closed-loop control system for the sense mode of a Microelectromechanica...

  • Article
  • Open Access
17 Citations
3,842 Views
10 Pages

Application of a Terahertz System Combined with an X-Shaped Metamaterial Microfluidic Cartridge

  • Shih-Ting Huang,
  • Shen-Fu Hsu,
  • Kai-Yuan Tang,
  • Ta-Jen Yen and
  • Da-Jeng Yao

9 January 2020

Terahertz (THz) radiation has attracted wide attention for its ability to sense molecular structure and chemical matter because of a label-free molecular fingerprint and nondestructive properties. When it comes to molecular recognition with terahertz...

  • Article
  • Open Access
10 Citations
5,430 Views
11 Pages

9 January 2020

The thermal management and channel temperature evaluation of GaN power amplifiers are indispensable issues in engineering field. The transient thermal characteristics of pulse operated AlGaN/GaN high electron mobility transistors (HEMT) used in high...

  • Review
  • Open Access
22 Citations
5,449 Views
17 Pages

Autonomous and In Situ Ocean Environmental Monitoring on Optofluidic Platform

  • Fang Wang,
  • Jiaomeng Zhu,
  • Longfei Chen,
  • Yunfeng Zuo,
  • Xuejia Hu and
  • Yi Yang

8 January 2020

Determining the distributions and variations of chemical elements in oceans has significant meanings for understanding the biogeochemical cycles, evaluating seawater pollution, and forecasting the occurrence of marine disasters. The primary chemical...

  • Article
  • Open Access
17 Citations
6,086 Views
14 Pages

8 January 2020

This paper reports an active catheter-tip device functionalized by integrating a temperature-responsive smart polymer onto a microfabricated flexible heater strip, targeting at enabling the controlled steering of catheters through complex vascular ne...

  • Article
  • Open Access
2 Citations
4,041 Views
15 Pages

7 January 2020

In this paper, a novel T-channel field effect transistor with three input terminals (Ti-TcFET) is proposed. The channel of a Ti-TcFET consists of horizontal and vertical sections. The top gate is above the horizontal channel, while the front gate and...

  • Article
  • Open Access
13 Citations
5,600 Views
7 Pages

A 45 nm CMOS Avalanche Photodiode with 8.4-GHz Bandwidth

  • Wenhao Zhi,
  • Qingxiao Quan,
  • Pingping Yu and
  • Yanfeng Jiang

7 January 2020

Photodiode is one of the key components in optoelectronic technology, which is used to convert optical signal into electrical ones in modern communication systems. In this paper, an avalanche photodiode (APD) is designed and fulfilled, which is compa...

  • Article
  • Open Access
13 Citations
4,632 Views
14 Pages

Micro Electrochemical Machining of Array Micro-Grooves Using In-Situ Disk Electrode Fabricated by Micro-WEDM

  • Yukui Wang,
  • Han Wang,
  • Yuxin Zhang,
  • Xiaolong He,
  • Zhenlong Wang,
  • Guanxin Chi,
  • Xiang Chen and
  • Mingshan Song

7 January 2020

This paper develops an array micro-grooves manufacturing method using micro electrochemical machining (ECM) with disk electrode, which is prepared by in-situ micro wire electrical discharge machining (WEDM). This technology focuses on the difficulty...

  • Article
  • Open Access
10 Citations
4,714 Views
15 Pages

Hand-Powered Elastomeric Pump for Microfluidic Point-of-Care Diagnostics

  • Gangadhar Eluru,
  • Jayesh Vasudeva Adhikari,
  • Priyalaxita Chanda and
  • Sai Siva Gorthi

7 January 2020

The pumping of fluids into microfluidic channels has become almost an unavoidable operation in all microfluidic applications. Such a need has seen an outburst of several techniques for pumping, out of which the majority of techniques involve complica...

  • Article
  • Open Access
31 Citations
7,129 Views
15 Pages

5 January 2020

As an important means to protect water resources, water quality detection is of great social and economic significance. Water quality detection sensors processed by micro-electro-mechanical system (MEMS) technology have the advantages of low-cost, sm...

  • Article
  • Open Access
4 Citations
5,273 Views
11 Pages

5 January 2020

Collagen peptides are an alternative to animal derived collagens for platelet function studies under flow. The purpose of this study was to examine the use of collagen peptides in polydimethylsiloxane (PDMS) devices. Three collagen peptides with amin...

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Micromachines - ISSN 2072-666X