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Open AccessReview

Microfluidics Mediated Production of Foams for Biomedical Applications

1
Microfluidics, MEMS, Nanostructures Laboratory, CNRS Chimie Biologie Innovation (CBI) UMR 8231, Institut Pierre Gilles de Gennes (IPGG), ESPCI Paris, PSL Research University, 6 rue Jean Calvin, 75005 Paris, France
2
Molecular, Macromolecular Chemistry and Materials, ESPCI Paris, CNRS, PSL University, 10 Rue Vauquelin, 75231 Paris, CEDEX 5, France
*
Author to whom correspondence should be addressed.
These authors contributed equally to this work.
Micromachines 2020, 11(1), 83; https://doi.org/10.3390/mi11010083
Received: 22 November 2019 / Revised: 6 January 2020 / Accepted: 7 January 2020 / Published: 12 January 2020
(This article belongs to the Special Issue Micro/Nano-system for Drug Delivery)
Within the last decade, there has been increasing interest in liquid and solid foams for several industrial uses. In the biomedical field, liquid foams can be used as delivery systems for dermatological treatments, for example, whereas solid foams are frequently used as scaffolds for tissue engineering and drug screening. Most of the foam functionalities are largely correlated to their mechanical properties and their structure, especially bubble/pore size, shape, and interconnectivity. However, the majority of conventional foaming fabrication techniques lack pore size control which can induce important inhomogeneities in the foams and subsequently decrease their performance. In this perspective, new advanced technologies have been introduced, such as microfluidics, which offers a highly controlled production, allowing for design customization of both liquid foams and solid foams obtained through liquid-templating. This short review explores both the fabrication and the characterization of foams, with a focus on solid polymer foams, and sheds the light on how microfluidics can overcome some existing limitations, playing a crucial role in their production for biomedical applications, especially as scaffolds in tissue engineering.
Keywords: microfluidics, foams, polymer foams, tissue engineering, biomedical, scaffolds microfluidics, foams, polymer foams, tissue engineering, biomedical, scaffolds
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MDPI and ACS Style

Maimouni, I.; Cejas, C.M.; Cossy, J.; Tabeling, P.; Russo, M. Microfluidics Mediated Production of Foams for Biomedical Applications. Micromachines 2020, 11, 83.

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